Total Knee Replacement Study Subject
Item
tka subjects:
boolean
C0086511 (UMLS CUI [1,1])
C0681850 (UMLS CUI [1,2])
Patient need for Knee Arthroplasty Primary
Item
1. patients requiring primary knee arthroplasty;
boolean
C0686904 (UMLS CUI [1,1])
C0086511 (UMLS CUI [1,2])
C0205225 (UMLS CUI [1,3])
Osteoarthritis, Knee
Item
2. knee osteoarthritis;
boolean
C0409959 (UMLS CUI [1])
Bone Support Quantity Sufficient | Bone Support Quality Sufficient
Item
3. subject has sufficient quantity or quality of bone support;
boolean
C0262950 (UMLS CUI [1,1])
C1521721 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0205410 (UMLS CUI [1,4])
C0262950 (UMLS CUI [2,1])
C1521721 (UMLS CUI [2,2])
C0332306 (UMLS CUI [2,3])
C0205410 (UMLS CUI [2,4])
Absence Communicable Disease Joint Affected | Sepsis Absent
Item
4. subject has no previous or active infection in the affected joint or systemic infection;
boolean
C0332197 (UMLS CUI [1,1])
C0009450 (UMLS CUI [1,2])
C0022417 (UMLS CUI [1,3])
C0392760 (UMLS CUI [1,4])
C0243026 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Study Subject Available Follow-up
Item
5. subject judged to be available for follow-up through at least 1 year postoperative;
boolean
C0681850 (UMLS CUI [1,1])
C0470187 (UMLS CUI [1,2])
C3274571 (UMLS CUI [1,3])
Arthroplasty Groups Age
Item
6. all subjects in arthroplasty groups will be between 50-70 years of age
boolean
C0003893 (UMLS CUI [1,1])
C0441833 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
Healthy Volunteers
Item
healthy subjects:
boolean
C1708335 (UMLS CUI [1])
Knee pain Absent | Operative procedure on knee Absent | Knee Arthritic change Absent
Item
1. healthy subjects will have no complaints of knee pain or history of knee surgery or known arthritic knee changes.
boolean
C0231749 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0187769 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0022742 (UMLS CUI [3,1])
C0741221 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])
Arthroplasty Lower Extremity Absent | Systemic disease Absent | Interference Research results Absent
Item
2. all subjects will have no history of prior lower extremity arthroplasty surgeries or systemic disease which could confound outcome measures.
boolean
C0003893 (UMLS CUI [1,1])
C0023216 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C0442893 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0521102 (UMLS CUI [3,1])
C0683954 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])
Age
Item
3. all healthy persons will be 40-70 years.
boolean
C0001779 (UMLS CUI [1])
Bone Support Quantity Insufficient | Bone Support Quality Insufficient | Malignant Neoplasms | Osteotomy Femoral | Osteoporosis | Metabolic Diseases Tissue Calcified
Item
1. insufficient quantity or quality of bone support resulting from conditions such as cancer, femoral osteotomy, significant osteoporosis or metabolic disorders of calcified tissues;
boolean
C0262950 (UMLS CUI [1,1])
C1521721 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0231180 (UMLS CUI [1,4])
C0262950 (UMLS CUI [2,1])
C1521721 (UMLS CUI [2,2])
C0332306 (UMLS CUI [2,3])
C0231180 (UMLS CUI [2,4])
C0006826 (UMLS CUI [3])
C0029468 (UMLS CUI [4,1])
C0015811 (UMLS CUI [4,2])
C0029456 (UMLS CUI [5])
C0025517 (UMLS CUI [6,1])
C0040300 (UMLS CUI [6,2])
C0175895 (UMLS CUI [6,3])
Patient unavailable Follow-up X-ray | Patient unavailable Follow-up Clinical Evaluation
Item
2. unable to return for follow up x-rays and clinical evaluation;
boolean
C1301818 (UMLS CUI [1,1])
C3274571 (UMLS CUI [1,2])
C0034571 (UMLS CUI [1,3])
C1301818 (UMLS CUI [2,1])
C3274571 (UMLS CUI [2,2])
C4084924 (UMLS CUI [2,3])
Comprehension Study Protocol Unable
Item
3. unable to comprehending study protocol for any reason;
boolean
C0162340 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
Inflammatory joint disease Systemic | Rheumatoid Arthritis | Communicable Disease | Patient need for Revision Operative procedure on knee
Item
4. systemic inflammatory joint disease (rheumatoid arthritis), previous infection or those requiring revision knee surgery;
boolean
C0683381 (UMLS CUI [1,1])
C0205373 (UMLS CUI [1,2])
C0003873 (UMLS CUI [2])
C0009450 (UMLS CUI [3])
C0686904 (UMLS CUI [4,1])
C1527075 (UMLS CUI [4,2])
C0187769 (UMLS CUI [4,3])
Immune System Disease | Therapeutic immunosuppression | Disease Response Limited Antigen Stimulus | Adrenal Cortex Hormones Large amount | Cytotoxic agent | Antilymphocytic serum | Therapeutic radiology procedure Dose Large | Therapeutic procedure Preventing Homograft reaction | Acquired Immunodeficiency Syndrome | Autoimmune Diseases
Item
5. subject has an immunological disorder: immunosuppressive treatment characterized by markedly inhibited ability to respond to antigenic stimuli. examples of such conditions include subjects who are on immunosuppressive therapy (corticosteroid hormones in large amounts, cytotoxic drugs, antilymphocytic serum or irradiation in large doses), subjects receiving therapy to prevent homograft rejection, subjects who have a documented history of acquired immunodeficiency syndrome (aids), or auto-immune diseases;
boolean
C0021053 (UMLS CUI [1])
C0021079 (UMLS CUI [2])
C1704632 (UMLS CUI [3,1])
C0439801 (UMLS CUI [3,2])
C0003320 (UMLS CUI [3,3])
C0234402 (UMLS CUI [3,4])
C0001617 (UMLS CUI [4,1])
C3869890 (UMLS CUI [4,2])
C0304497 (UMLS CUI [5])
C3826731 (UMLS CUI [6])
C1522449 (UMLS CUI [7,1])
C0178602 (UMLS CUI [7,2])
C0549177 (UMLS CUI [7,3])
C0087111 (UMLS CUI [8,1])
C1292733 (UMLS CUI [8,2])
C1268810 (UMLS CUI [8,3])
C0001175 (UMLS CUI [9])
C0004364 (UMLS CUI [10])
Nervous system problem Influence Biomechanical assessment Body Movement
Item
6. subject has a neurologic condition that would influence the results of biomechanical analysis of whole body movement.
boolean
C0221571 (UMLS CUI [1,1])
C4054723 (UMLS CUI [1,2])
C0846602 (UMLS CUI [1,3])
C0026649 (UMLS CUI [1,4])