Degenerative polyarthritis | Knee pain | Knee stiff | Osteophyte Radiography | Degenerative polyarthritis Medial compartment of knee Radiography | Disease Lateral compartment of knee Absent | Other Coding
Item
trial participants must meet american college of rheumatology (acr) criteria for osteoarthritis with knee pain, aching or stiffness on most of the past 30 days and evidence on radiograph of a definite osteophyte. in addition, because the researchers are interested in recruiting persons with medial knee osteoarthritis, participants will need to have evidence of disease in this compartment on their radiographs, and not have lateral compartment or patellofemoral compartment disease. medial disease is based on definitions used in the researcher's previous publications as definite radiographic oa + at least grade 1 medial narrowing (0-3 scale) using an atlas from the osteoarthritis research society international.
boolean
C0029408 (UMLS CUI [1])
C0231749 (UMLS CUI [2])
C0240129 (UMLS CUI [3])
C1956089 (UMLS CUI [4,1])
C0034571 (UMLS CUI [4,2])
C0029408 (UMLS CUI [5,1])
C0447799 (UMLS CUI [5,2])
C0034571 (UMLS CUI [5,3])
C0012634 (UMLS CUI [6,1])
C0447800 (UMLS CUI [6,2])
C0332197 (UMLS CUI [6,3])
C3846158 (UMLS CUI [7])
Disorder of patellofemoral joint | Disorder of knee Causing Knee pain | Exception Degenerative polyarthritis Medial compartment of knee
Item
individuals with clinical evidence of patellofemoral disease or knee pathology (other than medial compartment oa) likely to be causing their knee pain.
boolean
C0409325 (UMLS CUI [1])
C1290879 (UMLS CUI [2,1])
C0678227 (UMLS CUI [2,2])
C0231749 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0029408 (UMLS CUI [3,2])
C0447799 (UMLS CUI [3,3])
Ambulation with walking aid | Cane | Crutches | Walkers | Wheelchair
Item
individuals who usually use an ambulation aid to walk such as a cane, crutch, walker or wheel chair.
boolean
C3695267 (UMLS CUI [1])
C0006856 (UMLS CUI [2])
C0010397 (UMLS CUI [3])
C0043016 (UMLS CUI [4])
C0043143 (UMLS CUI [5])
Amputated foot | Major injury Foot | Lesions on foot | Skin sore on foot | Foot Ulcer
Item
amputation of foot or previous major trauma to foot that would raise concerns about whether an insert might worsen foot pain. persons with foot lesions such as sores or ulcers in which redistributing load in the foot might be dangerous, will be excluded.
boolean
C0576410 (UMLS CUI [1])
C0332677 (UMLS CUI [2,1])
C0016504 (UMLS CUI [2,2])
C0744147 (UMLS CUI [3])
C2231857 (UMLS CUI [4])
C0085119 (UMLS CUI [5])
Neuropathy Due to Diabetes Mellitus | Neuropathy Due to Other Reason
Item
known neuropathy from diabetes or for other reasons.
boolean
C0442874 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0011849 (UMLS CUI [1,3])
C0442874 (UMLS CUI [2,1])
C0678226 (UMLS CUI [2,2])
C3840932 (UMLS CUI [2,3])
Deep Vein Thrombosis
Item
past history of deep venous thrombosis.
boolean
C0149871 (UMLS CUI [1])
Back Pain | Hip pain | Screening questionnaire
Item
pain emanating more from back or hip than from knee as determined by screening questionnaire
boolean
C0004604 (UMLS CUI [1])
C0019559 (UMLS CUI [2])
C1134635 (UMLS CUI [3])
Pain low Knee eligible | WOMAC scale
Item
low pain score on womac, a widely used and well validated questionnaire to assess knee symptoms. to evaluate response, the researchers will require that patients have a minimal score of at least 4 out of 10 on at least 2 of 5 questions, or a total of greater than 15 out of 50 for the womac pain scale in the eligible knee at pre-randomization phone call and visit, and at randomization visit. this will allow us to detect response to treatment if response occurs.
boolean
C0030193 (UMLS CUI [1,1])
C0205251 (UMLS CUI [1,2])
C0022742 (UMLS CUI [1,3])
C1548635 (UMLS CUI [1,4])
C3472647 (UMLS CUI [2])
Relocation of home Planned
Item
planning to move from area within 9 months of study screening
boolean
C2699029 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
Comorbidity Symptomatic Limiting Walking | Knee pain | Screening questionnaire
Item
symptomatic comorbid disease limits walking more than knee pain (per screening questionnaire)
boolean
C0009488 (UMLS CUI [1,1])
C0231220 (UMLS CUI [1,2])
C0439801 (UMLS CUI [1,3])
C0080331 (UMLS CUI [1,4])
C0231749 (UMLS CUI [2])
C1134635 (UMLS CUI [3])
Adrenal Cortex Hormones Injection | Glucosamine | Chondroitin | NSAIDs
Item
receiving corticosteroid injections in the month prior to starting the trial. no other treatments will trigger exclusion, although for patients who have been on glucosamine +/or chondroitin +/or nonsteroidal anti-inflammatory drug (nsaid) the researchers will require that they must have taken these treatments for at least 2 months prior to onset of trial and to commit to not start a new treatment throughout the trial.
boolean
C0001617 (UMLS CUI [1,1])
C1828121 (UMLS CUI [1,2])
C0017718 (UMLS CUI [2])
C0008454 (UMLS CUI [3])
C0003211 (UMLS CUI [4])
Replacement of total knee joint Bilateral | Replacement of total knee joint Planned
Item
bilateral total knee replacements (tkr) or plan for tkr in next 6 months for affected knee.
boolean
C2316964 (UMLS CUI [1,1])
C0238767 (UMLS CUI [1,2])
C2316964 (UMLS CUI [2,1])
C1301732 (UMLS CUI [2,2])
Etiology Arthritis | Rheumatoid Arthritis | Lupus Erythematosus, Systemic | Gout | Arthritis, Psoriatic | Pseudogout
Item
known other causes of arthritis including rheumatoid arthritis (ra), systemic lupus erythematosus (sle), gout, psoriatic arthritis, pseudogout.
boolean
C0015127 (UMLS CUI [1,1])
C0003864 (UMLS CUI [1,2])
C0003873 (UMLS CUI [2])
C0024141 (UMLS CUI [3])
C0018099 (UMLS CUI [4])
C0003872 (UMLS CUI [5])
C0033802 (UMLS CUI [6])
Run-in Test failed
Item
failure to pass 4 week run-in test.
boolean
C3274438 (UMLS CUI [1,1])
C0039593 (UMLS CUI [1,2])
C0231175 (UMLS CUI [1,3])
Volunteers Precontemplation stage
Item
volunteers in a pre-contemplative state (persons who would not consider realignment therapy as a therapeutic option for their knee oa).
boolean
C3661466 (UMLS CUI [1,1])
C1277197 (UMLS CUI [1,2])