Chronic Kidney Disease Stage | Age | Serum phosphate level normal
Item
we will include stage 3a, 3b and 4 ckd patients, aged 18 years or over with normal serum phosphate levels (≤ 4.6 mg/dl)
boolean
C1561643 (UMLS CUI [1,1])
C2074731 (UMLS CUI [1,2])
C0001779 (UMLS CUI [2])
C0580488 (UMLS CUI [3])
Kidney Failure Advanced Rapidly | Hyperphosphatemia Development | Chronic Kidney Failure Requirement Dialysis
Item
patients with rapidly advancing renal failure who thus might develop hyperphosphatemia or end stage renal disease requiring initiation of dialysis during the study period
boolean
C0035078 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C0456962 (UMLS CUI [1,3])
C0085681 (UMLS CUI [2,1])
C0243107 (UMLS CUI [2,2])
C0022661 (UMLS CUI [3,1])
C1514873 (UMLS CUI [3,2])
C0011946 (UMLS CUI [3,3])
Dialysis Initiation Expected
Item
patients expected to require dialysis initiation within the follow up period
boolean
C0011946 (UMLS CUI [1,1])
C1704686 (UMLS CUI [1,2])
C1517001 (UMLS CUI [1,3])
Hyperphosphatemia
Item
patients with hyperphosphatemia > 4.6 mg/dl
boolean
C0085681 (UMLS CUI [1])
Phosphate Binders | Vitamin D | Doxercalciferol | Calcitriol
Item
patients with any previous or current treatment with phosphate binders or active vitamin d (doxercalciferol or calcitriol)
boolean
C4020599 (UMLS CUI [1])
C0042866 (UMLS CUI [2])
C0043668 (UMLS CUI [3])
C0006674 (UMLS CUI [4])
Malnutrition | Serum albumin measurement
Item
malnutrition, defined as a serum albumin < 3.0 mg/dl
boolean
C0162429 (UMLS CUI [1])
C0523465 (UMLS CUI [2])
Liver disease | Alanine aminotransferase measurement | Aspartate aminotransferase measurement | Cholestasis | Bilirubin, direct measurement | Limitation Absorption Fat soluble vitamin product | Limitation Absorption Vitamin D
Item
patients with liver disease (alt or ast > 100 u/l) or cholestasis (direct bilirubin > 1.0 mg/dl) because this can limit their ability to absorb fat soluble vitamins such as vitamin d
boolean
C0023895 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
C0201899 (UMLS CUI [3])
C0008370 (UMLS CUI [4])
C0201916 (UMLS CUI [5])
C0449295 (UMLS CUI [6,1])
C0237442 (UMLS CUI [6,2])
C0259753 (UMLS CUI [6,3])
C0449295 (UMLS CUI [7,1])
C0237442 (UMLS CUI [7,2])
C0042866 (UMLS CUI [7,3])
Anemia | Hematocrit procedure
Item
anemia, defined as a hematocrit < 27% at the screening visit
boolean
C0002871 (UMLS CUI [1])
C0018935 (UMLS CUI [2])
Medical condition Impact Phosphatidylinositol metabolic process | Hyperparathyroidism, Primary | Primary hypoparathyroidism | Subtotal parathyroidectomy | Malabsorption Syndrome | Crohn Disease | Ulcerative Colitis | Celiac Disease | Liver Dysfunction Severe
Item
medical conditions impacting pi metabolism—primary hyper- or hypoparathyroidism; patients with previous subtotal parathyroidectomy; gastrointestinal malabsorption disorders such as crohn's disease, ulcerative colitis, celiac disease, or severe liver dysfunction;
boolean
C3843040 (UMLS CUI [1,1])
C4049986 (UMLS CUI [1,2])
C1158430 (UMLS CUI [1,3])
C0221002 (UMLS CUI [2])
C3828476 (UMLS CUI [3])
C0193697 (UMLS CUI [4])
C0024523 (UMLS CUI [5])
C0010346 (UMLS CUI [6])
C0009324 (UMLS CUI [7])
C0007570 (UMLS CUI [8])
C0086565 (UMLS CUI [9,1])
C0205082 (UMLS CUI [9,2])
Outpatient Counseling Nutritionist renal
Item
patients with outpatient counseling by a renal nutritionist within the previous 6 months
boolean
C0029921 (UMLS CUI [1,1])
C0010210 (UMLS CUI [1,2])
C0237083 (UMLS CUI [1,3])
C0022646 (UMLS CUI [1,4])
Hospitalization
Item
hospitalization within the previous 4 weeks
boolean
C0019993 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
pregnancy or breastfeeding mothers
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Informed Consent Unable | Prisoners | Mental Incompetency | Minor
Item
patients unable to independently provide written informed consent - prisoners, mentally incompetent, minors
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
C0033167 (UMLS CUI [2])
C0086455 (UMLS CUI [3])
C0026193 (UMLS CUI [4])