Antihypertensive Agents naive | Antihypertensive Agents Previous Discontinued
Item
an antihypertensive-naive subject or a subject who has not been taking the previously administered antihypertensive agent for at least 4 weeks prior to screening
boolean
C0003364 (UMLS CUI [1,1])
C0919936 (UMLS CUI [1,2])
C0003364 (UMLS CUI [2,1])
C0205156 (UMLS CUI [2,2])
C1444662 (UMLS CUI [2,3])
Age
Item
subjects aged between 20 and 75 years, inclusive
boolean
C0001779 (UMLS CUI [1])
Systolic Pressure | Diastolic blood pressure
Item
subjects with systolic blood pressure (sbp) greater than or equal to 140 millimeter of mercury (mmhg) and less than 180 mmhg or diastolic blood pressure (dbp) greater than or equal to 90 mmhg and less than 110 mmhg
boolean
C0871470 (UMLS CUI [1])
C0428883 (UMLS CUI [2])
Secondary hypertension
Item
subjects with secondary hypertension
boolean
C0155616 (UMLS CUI [1])
Renal Insufficiency | Creatinine measurement, serum
Item
subjects with renal impairment (creatinine greater than 150 micromoles/liter [mcmol/l] or creatinine greater than 1.7 mg/deciliter [dl])
boolean
C1565489 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
Severe Hypertension Stage | Systolic Pressure | Diastolic blood pressure
Item
subjects with severe hypertension (stage iii) sbp greater than or equal to 180 mmhg or dbp greater than or equal to 110 mmhg
boolean
C4013784 (UMLS CUI [1,1])
C0699749 (UMLS CUI [1,2])
C0871470 (UMLS CUI [2])
C0428883 (UMLS CUI [3])
Congestive heart failure | Myocardial Infarction | Angina, Unstable
Item
subjects with congestive heart failure, acute myocardial infarction, unstable angina
boolean
C0018802 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
C0002965 (UMLS CUI [3])
Moderate asthma | Chronic Obstructive Airway Disease
Item
subjects with moderate bronchial asthma, chronic obstructive pulmonary disease
boolean
C0581125 (UMLS CUI [1])
C0024117 (UMLS CUI [2])
BRADYCARDIA SYMPTOMATIC | Injury of radial artery | Second degree atrioventricular block | Complete atrioventricular block | Atrial Fibrillation | Atrial Flutter | Left Bundle-Branch Block
Item
subjects with symptomatic bradycardia, radial artery injury, second degree or third degree atrioventricular (av) block, atrial fibrillation, atrial flutter, left bundle branch block (lbbb)
boolean
C0741627 (UMLS CUI [1])
C0273474 (UMLS CUI [2])
C0264906 (UMLS CUI [3])
C0151517 (UMLS CUI [4])
C0004238 (UMLS CUI [5])
C0004239 (UMLS CUI [6])
C0023211 (UMLS CUI [7])
Bisoprolol allergy | Atenolol allergy
Item
subjects with a history of hypersensitivity to bisoprolol and atenolol products
boolean
C0570886 (UMLS CUI [1])
C0570884 (UMLS CUI [2])
Pregnancy | Breast Feeding
Item
pregnancy or breastfeeding women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])