Essential Hypertension
Item
confirmed diagnosis of essential hypertension.
boolean
C0085580 (UMLS CUI [1])
Systolic Pressure | Diastolic blood pressure
Item
has systolic blood pressure between 150 mmhg and 200 mmhg and diastolic blood pressure between 110 mmhg and 120 mmhg.
boolean
C0871470 (UMLS CUI [1])
C0428883 (UMLS CUI [2])
Antihypertensive therapy Absent
Item
has not received any antihypertensive treatment so far.
boolean
C0585941 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Childbearing Potential Pregnancy test negative | Females & males of reproductive potential Contraceptive methods
Item
has a negative pregnancy test at baseline in females of childbearing potential. male and female participants with reproductive potential must use an approved contraceptive method during study treatment evaluation
boolean
C3831118 (UMLS CUI [1,1])
C0427780 (UMLS CUI [1,2])
C4034483 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
Secondary hypertension | Conn Syndrome | Secondary hypertension Suspected | Conn Syndrome Suspected
Item
has a known or suspected secondary hypertension or primary hyperaldosteronism.
boolean
C0155616 (UMLS CUI [1])
C1384514 (UMLS CUI [2])
C0155616 (UMLS CUI [3,1])
C0750491 (UMLS CUI [3,2])
C1384514 (UMLS CUI [4,1])
C0750491 (UMLS CUI [4,2])
Renal Insufficiency
Item
has impaired renal function.
boolean
C1565489 (UMLS CUI [1])
Hepatic impairment Severe
Item
has severe hepatic impairment.
boolean
C0948807 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
Bilateral renal artery stenosis | Kidney Solitary | Status post Kidney Transplantation
Item
has bilateral renal artery stenosis, solitary kidney or post-renal transplant status.
boolean
C0856760 (UMLS CUI [1])
C0022646 (UMLS CUI [2,1])
C0205171 (UMLS CUI [2,2])
C0231290 (UMLS CUI [3,1])
C0022671 (UMLS CUI [3,2])
Myocardial Infarction | Coronary Artery Bypass Surgery | Percutaneous Coronary Intervention | Cerebrovascular accident | Transient Ischemic Attack
Item
has a history of myocardial infarction, coronary artery bypass graft, percutaneous coronary intervention or cerebral accident (stroke or transient ischaemic attack) within the last 6 months.
boolean
C0027051 (UMLS CUI [1])
C0010055 (UMLS CUI [2])
C1532338 (UMLS CUI [3])
C0038454 (UMLS CUI [4])
C0007787 (UMLS CUI [5])
Hypertrophic Cardiomyopathy | Angina Pectoris | Chronic heart failure | Peripheral arterial occlusive disease | Hypertensive Retinopathy | Hypertrophic Cardiomyopathy Suspicion | Angina Pectoris Suspicion | Chronic heart failure Suspicion | Peripheral arterial occlusive disease Suspicion | Hypertensive Retinopathy Suspicion
Item
has a diagnosis or suspicion of the following conditions: hypertrophic obstructive cardiomyopathy, angina pectoris, chronic heart failure, peripheral arterial occlusive disease, hypertensive retinopathy.
boolean
C0007194 (UMLS CUI [1])
C0002962 (UMLS CUI [2])
C0264716 (UMLS CUI [3])
C1306889 (UMLS CUI [4])
C0152132 (UMLS CUI [5])
C0007194 (UMLS CUI [6,1])
C0242114 (UMLS CUI [6,2])
C0002962 (UMLS CUI [7,1])
C0242114 (UMLS CUI [7,2])
C0264716 (UMLS CUI [8,1])
C0242114 (UMLS CUI [8,2])
C1306889 (UMLS CUI [9,1])
C0242114 (UMLS CUI [9,2])
C0152132 (UMLS CUI [10,1])
C0242114 (UMLS CUI [10,2])
Aortic Valve Stenosis | Mitral Valve Stenosis
Item
has hemodynamically relevant stenosis of the aortic or mitral valve.
boolean
C0003507 (UMLS CUI [1])
C0026269 (UMLS CUI [2])
Hypokalemia refractory | Hyperkalemia refractory
Item
has clinically relevant and refractory hypokalaemia or hyperkalaemia.
boolean
C0020621 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
C0020461 (UMLS CUI [2,1])
C0205269 (UMLS CUI [2,2])
Hypovolemia uncorrected | Hyponatremia uncorrected
Item
has uncorrected volume or sodium depletion.
boolean
C0546884 (UMLS CUI [1,1])
C4072785 (UMLS CUI [1,2])
C0020625 (UMLS CUI [2,1])
C4072785 (UMLS CUI [2,2])
Gout | Hyperuricemia
Item
has gout or relevant hyperuricaemia.
boolean
C0018099 (UMLS CUI [1])
C0740394 (UMLS CUI [2])
Intolerance to Candesartan cilexetil | Hypersensitivity Candesartan cilexetil | Intolerance to Hydrochlorothiazide | Hydrochlorothiazide allergy
Item
has a known intolerance/hypersensitivity to candesartan cilexetil or hydrochlorothiazide.
boolean
C1744706 (UMLS CUI [1,1])
C0527379 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0527379 (UMLS CUI [2,2])
C1744706 (UMLS CUI [3,1])
C0020261 (UMLS CUI [3,2])
C0571898 (UMLS CUI [4])
Galactosemias | Lactase deficiency | Glucose-galactose malabsorption
Item
has a known galactose intolerance, lactase deficiency or glucose-galactose malabsorption.
boolean
C0016952 (UMLS CUI [1])
C0302813 (UMLS CUI [2])
C0268186 (UMLS CUI [3])
Psychotropic Drugs | Substance Dependence
Item
is taking psychotropic medication or is addicted to alcohol or drugs.
boolean
C0033978 (UMLS CUI [1])
C0038580 (UMLS CUI [2])
Study Subject Participation Status | Investigational New Drugs | Investigational Medical Device
Item
has participated in another trial of an investigational drug or a medical device within the last 30 days or is currently participating in another trial of an investigational drug or a medical device.
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
C2346570 (UMLS CUI [3])