Age
Item
patients over 18 years of age
boolean
C0001779 (UMLS CUI [1])
Essential Hypertension | Blood Pressure Uncontrolled Before Clinical Trial | Sitting diastolic blood pressure Pharmacotherapy | Sitting diastolic blood pressure Pharmacotherapy naive
Item
essential hypertensive patients whose blood pressure is not controlled before the study (sit dbp ≥ 90 mmhg for drug-treated patient, sit dbp ≥ 95 mmhg for drug-naïve patient)
boolean
C0085580 (UMLS CUI [1])
C0005823 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
C0332152 (UMLS CUI [2,3])
C0008976 (UMLS CUI [2,4])
C1319894 (UMLS CUI [3,1])
C0013216 (UMLS CUI [3,2])
C1319894 (UMLS CUI [4,1])
C0013216 (UMLS CUI [4,2])
C0919936 (UMLS CUI [4,3])
Amlodipine Unresponsive to Treatment | Sitting diastolic blood pressure
Item
non-responder to 4 weeks treatment of amlodipine 5 mg monotherapy (sit dbp ≥ 90mmhg)
boolean
C0051696 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
C1319894 (UMLS CUI [2])
Sitting systolic blood pressure mean | Sitting diastolic blood pressure mean
Item
mean sit sbp ≥ 200 mmhg or mean sit dbp ≥ 120 mmhg at screening
boolean
C1319893 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
C1319894 (UMLS CUI [2,1])
C0444504 (UMLS CUI [2,2])
Sitting systolic blood pressure mean | Sitting diastolic blood pressure mean | Amlodipine
Item
mean sit sbp ≥ 180 mmhg or mean sit dbp ≥ 120 mmhg after 4 weeks of amlodipine 5 mg treatment
boolean
C1319893 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
C1319894 (UMLS CUI [2,1])
C0444504 (UMLS CUI [2,2])
C0051696 (UMLS CUI [3])
Hypersensitivity Dihydropyridines | Allergy to angiotensin II receptor antagonist
Item
has a history of hypersensitivity to dihydropyridines or angiotensin ii receptor blockers
boolean
C0020517 (UMLS CUI [1,1])
C0012315 (UMLS CUI [1,2])
C2585204 (UMLS CUI [2])
Secondary hypertension | Secondary hypertension Suspected
Item
secondary hypertensive patient or suspected to be
boolean
C0155616 (UMLS CUI [1])
C0155616 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
Diabetic - poor control
Item
uncontrolled diabetes mellitus patients
boolean
C0421258 (UMLS CUI [1])
Heart Disease Severe | Neurovascular Disorder Severe
Item
severe heart disease or severe neurovascular disease
boolean
C0018799 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C3898144 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
Retinal Disease Severe | Retinal Disease Malignant
Item
known as severe or malignant retinopathy
boolean
C0035309 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0035309 (UMLS CUI [2,1])
C0205282 (UMLS CUI [2,2])
Hematological Disease | Kidney Disease | Creatinine measurement, serum | Liver disease | Alanine aminotransferase measurement | Aspartate aminotransferase measurement
Item
patients showed clinically significant hematological finding, patients with renal diseases (serum creatinine), patients with hepatic disease (alt or ast)
boolean
C0018939 (UMLS CUI [1])
C0022658 (UMLS CUI [2])
C0201976 (UMLS CUI [3])
C0023895 (UMLS CUI [4])
C0201836 (UMLS CUI [5])
C0201899 (UMLS CUI [6])
Malignant Neoplasms
Item
history of malignancy tumor
boolean
C0006826 (UMLS CUI [1])
Autoimmune Disease
Item
history of autoimmune disease
boolean
C0004364 (UMLS CUI [1])
Substance Use Disorders
Item
history of alcohol or drug abuse
boolean
C0038586 (UMLS CUI [1])
Pregnancy test positive | Breast Feeding | Pregnancy, Planned
Item
positive to pregnancy test, nursing mother, has an intention on pregnancy
boolean
C0240802 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032992 (UMLS CUI [3])
Other Reason Study Subject Participation Status Inappropriate
Item
considered by investigator as not appropriate to participate in the clinical study with othe reason
boolean
C3840932 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C1548788 (UMLS CUI [1,3])