Patients Newly Diagnosed | Hypertensive disease untreated | Sitting diastolic blood pressure mean Visit Number
Item
newly diagnosed patients or patients who have not been treated for hypertension within the 4 weeks prior to visit 1 must have a mean sitting diastolic blood pressure (msdbp) ≥ 95 mmhg and < 110 mmhg at visits 1 and 2
boolean
C0030705 (UMLS CUI [1,1])
C1518321 (UMLS CUI [1,2])
C0020538 (UMLS CUI [2,1])
C0332155 (UMLS CUI [2,2])
C1319894 (UMLS CUI [3,1])
C0444504 (UMLS CUI [3,2])
C1549755 (UMLS CUI [3,3])
Therapeutic procedure Hypertensive disease | Sitting diastolic blood pressure mean Visit Number
Item
patients who have been treated for hypertension within the 4 weeks prior to - visit 1 must have a msdbp ≥ 90 mmhg and < 110 mmhg at visit 2
boolean
C0087111 (UMLS CUI [1,1])
C0020538 (UMLS CUI [1,2])
C1319894 (UMLS CUI [2,1])
C0444504 (UMLS CUI [2,2])
C1549755 (UMLS CUI [2,3])
Sitting diastolic blood pressure mean Visit Number
Item
all patients must have a msdbp ≥ 90 mmhg and < 110 mmhg at visit 4
boolean
C1319894 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
C1549755 (UMLS CUI [1,3])
Hypertension, severe
Item
severe hypertension
boolean
C4013784 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
pregnant or nursing (lactating) women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Childbearing Potential
Item
women of child-bearing potential
boolean
C3831118 (UMLS CUI [1])
Heart failure New York Heart Association Classification
Item
previous or current diagnosis of heart failure new york heart association (nyha class ii-iv)
boolean
C0018801 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Serum potassium measurement
Item
serum potassium ≥ 5.3 meq/l (mmol/l) at visit 1
boolean
C0302353 (UMLS CUI [1])
DIABETES MELLITUS INSULIN DEPENDENT UNCONTROLLED | DIABETES MELLITUS NON INSULIN DEPENDENT UNCONTROLLED
Item
uncontrolled type 1 or type 2 diabetes mellitus
boolean
C0743113 (UMLS CUI [1])
C0743118 (UMLS CUI [2])
Hypersensitivity Renin inhibitor | Calcium-channel blocker allergy | Hypersensitivity Pharmaceutical Preparations Chemical Structure Similar
Item
hypersensitivity to renin inhibitors, calcium channel blockers, or to drugs with similar chemical structures
boolean
C0020517 (UMLS CUI [1,1])
C1960108 (UMLS CUI [1,2])
C0570913 (UMLS CUI [2])
C0020517 (UMLS CUI [3,1])
C0013227 (UMLS CUI [3,2])
C0220807 (UMLS CUI [3,3])
C2348205 (UMLS CUI [3,4])
Hypertensive Encephalopathy | Cerebrovascular accident | Transient Ischemic Attack | Myocardial Infarction | Coronary Artery Bypass Surgery | Percutaneous Coronary Intervention
Item
history of hypertensive encephalopathy or cerebrovascular accident, or history of transient ischemic attack (tia), myocardial infarction, coronary bypass surgery, or any percutaneous coronary intervention
boolean
C0151620 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
C0007787 (UMLS CUI [3])
C0027051 (UMLS CUI [4])
C0010055 (UMLS CUI [5])
C1532338 (UMLS CUI [6])
Eligibility Criteria Study Protocol
Item
other protocol-defined inclusion/exclusion criteria may apply.
boolean
C1516637 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])