Patient Recruitment Clinics
Item
participants will be selected from a broad range of medical clinics at the salt lake city va medical center and surrounding community based outpatient clinics (cbocs).
boolean
C0242800 (UMLS CUI [1,1])
C0442592 (UMLS CUI [1,2])
Study Subject Referral to RESISTANT HYPERTENSION Clinic
Item
the participants will be referred to a resistant hypertension clinic by either their primary care provider or by a subspecialist. the referrals are made via a computerized system that is used in the veterans affairs medical center (va) called computerized patient record system (cprs).
boolean
C0681850 (UMLS CUI [1,1])
C2585021 (UMLS CUI [1,2])
C0745130 (UMLS CUI [1,3])
C0442592 (UMLS CUI [1,4])
Blood pressure determination | Antihypertensive Agents Quantity | Diuretics Quantity
Item
patients are referred if their blood pressure is above goal as defined by jnc 7 and they are on 3 antihypertensive medications with one of the agents being a diuretic.
boolean
C0005824 (UMLS CUI [1])
C0003364 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0012798 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
Age
Item
all patients age 18 -80 years old.
boolean
C0001779 (UMLS CUI [1])
Spironolactone adverse reaction | Amiloride adverse reaction
Item
patients that will be excluded from the study if they have had a documented adverse reaction to either spironolactone or amiloride.
boolean
C0414009 (UMLS CUI [1])
C0414008 (UMLS CUI [2])
Conn Syndrome
Item
diagnosis of primary hyperaldosteronism
boolean
C1384514 (UMLS CUI [1])
Monitoring of laboratory results Frequent Unable
Item
inability to adhere to frequent laboratory monitoring
boolean
C3165364 (UMLS CUI [1,1])
C0332183 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
Estimated Glomerular Filtration Rate
Item
estimated glomerular filtration rate (gfr) < 45 ml/min/1.73m2
boolean
C3811844 (UMLS CUI [1])
Serum potassium measurement
Item
baseline serum potassium above 5.0 meq/l
boolean
C0302353 (UMLS CUI [1])
Renal tubular acidosis Type
Item
type 4 renal tubular acidosis
boolean
C0001126 (UMLS CUI [1,1])
C0332307 (UMLS CUI [1,2])
Pregnancy
Item
pregnancy
boolean
C0032961 (UMLS CUI [1])
Heart failure | Eplerenone | Spironolactone
Item
heart failure that meets criteria for using either eplerenone or spironolactone
boolean
C0018801 (UMLS CUI [1])
C0961485 (UMLS CUI [2])
C0037982 (UMLS CUI [3])
Renal function Unstable
Item
current unstable renal function
boolean
C0232804 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])