Age
Item
aged over 18 years
boolean
C0001779 (UMLS CUI [1])
Essential Hypertension | Secondary hypertension
Item
hypertension (essential or secondary) managed in sheffield hypertension clinic or general practice or both.
boolean
C0085580 (UMLS CUI [1])
C0155616 (UMLS CUI [2])
Blood Pressure Poorly controlled | Systolic Pressure | Diastolic blood pressure | Antihypertensive Agents Quantity Maximum Tolerated Dose
Item
blood pressures not adequately controlled (systolic blood pressure (sbp) >140 mmhg and/or diastolic blood pressure (dbp) >85 mmhg in clinic and on ambulatory blood pressure monitoring) despite treatment with the maximum tolerated dose of three antihypertensive agents.
boolean
C0005823 (UMLS CUI [1,1])
C3853134 (UMLS CUI [1,2])
C0871470 (UMLS CUI [2])
C0428883 (UMLS CUI [3])
C0003364 (UMLS CUI [4,1])
C1265611 (UMLS CUI [4,2])
C0752079 (UMLS CUI [4,3])
Antihypertensive therapy Additional Appropriate
Item
additional antihypertensive treatment deemed appropriate by the patients' doctor.
boolean
C0585941 (UMLS CUI [1,1])
C1524062 (UMLS CUI [1,2])
C1548787 (UMLS CUI [1,3])
Antihypertensive therapy | Thiazide Diuretic | Adrenergic beta-1 Receptor Antagonists Quantity | Angiotensin-Converting Enzyme Inhibitors Quantity | Angiotensin II receptor antagonist Quantity
Item
patients' current antihypertensive treatment includes a thiazide diuretic and at least one of a beta-blocker, angiotensin converting enzyme inhibitor or angiotensin ii receptor antagonist.
boolean
C0585941 (UMLS CUI [1])
C0012802 (UMLS CUI [2])
C0304516 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
C0003015 (UMLS CUI [4,1])
C1265611 (UMLS CUI [4,2])
C0521942 (UMLS CUI [5,1])
C1265611 (UMLS CUI [5,2])
Indication Spironolactone | Medical contraindication Spironolactone
Item
definite indication or contraindication for spironolactone
boolean
C3146298 (UMLS CUI [1,1])
C0037982 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0037982 (UMLS CUI [2,2])
Conn Syndrome | Indication Spironolactone
Item
known conn's syndrome (definite indication for spironolactone)
boolean
C1384514 (UMLS CUI [1])
C3146298 (UMLS CUI [2,1])
C0037982 (UMLS CUI [2,2])
Heart failure New York Heart Association Classification | Indication Spironolactone
Item
heart failure nyha class iii or iv (definite indication for spironolactone)
boolean
C0018801 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
C3146298 (UMLS CUI [2,1])
C0037982 (UMLS CUI [2,2])
Liver Failure | Liver Cirrhosis
Item
known hepatic failure or significant cirrhosis
boolean
C0085605 (UMLS CUI [1])
C0023890 (UMLS CUI [2])
Pregnancy | Pregnancy, Planned
Item
known pregnancy or women planning pregnancy
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
Childbearing Potential Contraceptive methods Absent
Item
women of child bearing potential not using adequate contraceptive methods
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Creatinine measurement, serum
Item
serum creatinine > 221µmol/l
boolean
C0201976 (UMLS CUI [1])
Serum potassium measurement
Item
serum potassium > 5.0mmol/l
boolean
C0302353 (UMLS CUI [1])
Blood pressure determination Clinic | Blood pressure ambulatory Daytime
Item
clinic blood pressure or daytime ambulatory blood pressure >240/120
boolean
C0005824 (UMLS CUI [1,1])
C0442592 (UMLS CUI [1,2])
C0855316 (UMLS CUI [2,1])
C0332169 (UMLS CUI [2,2])