HIV Infection | AIDS | Hepatitis C | Hepatitis C Mild | Healthy | Medical History | Physical Examination | Laboratory Procedures | Urinalysis | Eligibility HAART
Item
participants will be diagnosed with hiv/aids, hiv/aids and hepatitis c, mild hepatitis c or will be healthy as determined by history and physical examination, screening laboratory tests and urinalysis, and will be eligible for treatment with haart
boolean
C0019693 (UMLS CUI [1])
C0001175 (UMLS CUI [2])
C0019196 (UMLS CUI [3])
C0019196 (UMLS CUI [4,1])
C2945599 (UMLS CUI [4,2])
C3898900 (UMLS CUI [5])
C0262926 (UMLS CUI [6])
C0031809 (UMLS CUI [7])
C0022885 (UMLS CUI [8])
C0042014 (UMLS CUI [9])
C1548635 (UMLS CUI [10,1])
C0887947 (UMLS CUI [10,2])
Alcohol consumption
Item
participants will be experienced with alcohol consumption
boolean
C0001948 (UMLS CUI [1])
Alcohol abuse | Alcoholic Intoxication, Chronic | Opiate Addiction Absent | Stimulant dependence Absent | Cannabis Dependence Absent | Hallucinogen dependence Absent | Other Substance Dependence Absent
Item
they may meet diagnostic criteria for alcohol abuse or non-physiological alcohol dependence, but may not be dependent on any other substances including opioids, stimulants, cannabis, hallucinogens or other substances, prescribed or illicit
boolean
C0085762 (UMLS CUI [1])
C0001973 (UMLS CUI [2])
C0524662 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C2711618 (UMLS CUI [4,1])
C0332197 (UMLS CUI [4,2])
C0006870 (UMLS CUI [5,1])
C0332197 (UMLS CUI [5,2])
C0018528 (UMLS CUI [6,1])
C0332197 (UMLS CUI [6,2])
C0236933 (UMLS CUI [7,1])
C0332197 (UMLS CUI [7,2])
HCV coinfection | Hepatitis C Consistent with Mild Liver fibrosis | Fibrosis stage Assessment | Other Coding
Item
for those with hcv coinfection, hcv must be at a stage consistent with no more than mild liver fibrosis (fibrosis stage assessed by two methods: the ast to platelet ratio (apri) (at a score of <0.5 for eligibility) and the fib-4 fibrosis index (score of <1.5 for eligibility), both of which indicate mild liver disease.)
boolean
C1698259 (UMLS CUI [1])
C0019196 (UMLS CUI [2,1])
C0332290 (UMLS CUI [2,2])
C4227681 (UMLS CUI [2,3])
C1954435 (UMLS CUI [3,1])
C1516048 (UMLS CUI [3,2])
C3846158 (UMLS CUI [4])
Age
Item
age 21 or older
boolean
C0001779 (UMLS CUI [1])
Hemoglobin measurement | Gender
Item
hemoglobin men > 11 g/dl, women > 10 g/dl5
boolean
C0518015 (UMLS CUI [1])
C0079399 (UMLS CUI [2])
Informed Consent
Item
able to give voluntary, signed, informed consent.
boolean
C0021430 (UMLS CUI [1])
Pharmaceutical Preparations Inducing Microsomal enzymes Hepatic | Microsomal enzymes Hepatic Inhibitors
Item
patients who are receiving concurrently other drugs that are inducers or inhibitors of hepatic microsomal enzymes
boolean
C0013227 (UMLS CUI [1,1])
C0205263 (UMLS CUI [1,2])
C0815014 (UMLS CUI [1,3])
C0205054 (UMLS CUI [1,4])
C0815014 (UMLS CUI [2,1])
C0205054 (UMLS CUI [2,2])
C0243077 (UMLS CUI [2,3])
Hypersensitivity Anti-HIV Agents Investigational
Item
patients with a known sensitivity to the hiv therapeutics to be studied
boolean
C0020517 (UMLS CUI [1,1])
C0376565 (UMLS CUI [1,2])
C1517586 (UMLS CUI [1,3])
Pregnancy | Breast Feeding
Item
pregnant women or nursing mothers.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Childbearing Potential Sexually active Pregnancy test negative
Item
all women who are sexually active and capable of becoming pregnant must have a negative pregnancy test within one week prior to entry into these studies.
boolean
C3831118 (UMLS CUI [1,1])
C0241028 (UMLS CUI [1,2])
C0427780 (UMLS CUI [1,3])
Psychotic illness Major | Suicidality
Item
major psychotic illness or suicidality.
boolean
C1860474 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
C3166387 (UMLS CUI [2])
Hepatitis | Elevated liver enzymes | Liver Fibrosis Moderate | Liver Fibrosis Severe
Item
clinically active hepatitis with liver enzyme elevations > 3 times the upper limit of normal or evidence of liver fibrosis at a stage indicative of greater than mild stage for fibrosis (see inclusion criteria).
boolean
C0019158 (UMLS CUI [1])
C0235996 (UMLS CUI [2])
C0239946 (UMLS CUI [3,1])
C0205081 (UMLS CUI [3,2])
C0239946 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
Obesity | Body mass index | Diabetes Mellitus | Hyperlipidemia | Blood Coagulation Disorders | Kidney Diseases
Item
those with obesity (bmi > 30), diabetes, hyperlipidemia, coagulation disorders, or renal disease will be excluded.
boolean
C0028754 (UMLS CUI [1])
C1305855 (UMLS CUI [2])
C0011849 (UMLS CUI [3])
C0020473 (UMLS CUI [4])
C0005779 (UMLS CUI [5])
C0022658 (UMLS CUI [6])
Hemoglobin measurement | Gender
Item
hemoglobin men < 11 g/dl, women < 10 g/dl
boolean
C0518015 (UMLS CUI [1])
C0079399 (UMLS CUI [2])
Alcoholic Intoxication, Chronic
Item
physical dependence on alcohol.
boolean
C0001973 (UMLS CUI [1])