Gender | Age | Informed Consent | Liver carcinoma Evolving Liver Cirrhosis | Biopsy of liver
Item
cases and controls will be males aged 35 or older, and will give an informed consent to participate in the study. all hcc cases evolving in cirrhotic liver, whatever the etiology of cirrhosis, will be included. criteria for the diagnosis of hcc will be those defined by the european association for study of the liver (easl) (bruix j, j hepatol 2001): all patients with cirrhosis, whatever its etiology, will be included. the diagnosis of cirrhosis will rely on histological confirmation by liver biopsy:
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0021430 (UMLS CUI [3])
C2239176 (UMLS CUI [4,1])
C0332253 (UMLS CUI [4,2])
C0023890 (UMLS CUI [4,3])
C0193388 (UMLS CUI [5])
Portal thrombosis Free of Doppler Ultrasound Imaging | Hypertension, Portal | Pancytopenia | Abdominal Ultrasound | CT of abdomen | MRI of abdomen | Hepatic venous pressure gradient | Endoscopy of stomach | Stomach Diseases | Gastric Varices
Item
in patients free of portal thrombosis at doppler imaging, on the presence of portal hypertension ascertained by biological (tricytopenia), morphologic (abdominal us, ct or mri), hepatic venous pressure measurement or upper endoscopy (mosaic gastropathy, varices).
boolean
C0155773 (UMLS CUI [1,1])
C0332296 (UMLS CUI [1,2])
C2713308 (UMLS CUI [1,3])
C0020541 (UMLS CUI [2])
C0030312 (UMLS CUI [3])
C2348813 (UMLS CUI [4])
C0412620 (UMLS CUI [5])
C0412693 (UMLS CUI [6])
C4049263 (UMLS CUI [7])
C0017195 (UMLS CUI [8])
C0038354 (UMLS CUI [9])
C0017145 (UMLS CUI [10])
Portal vein thrombosis | Hypertension, Portal
Item
in patients with portal thrombosis, on the presence of portal hypertension associated with:
boolean
C0155773 (UMLS CUI [1])
C0020541 (UMLS CUI [2])
Signs Liver Cirrhosis | Hepatomegaly | Failure Hepatocellular | Spider nevus | Palmar erythema | White nails | Gynecomastia | Signs morphological Liver Cirrhosis | Hepatomegaly | Surface Nodular | Liver edge Lower
Item
clinical (hepatomegaly with clinical evidence of hepatocellular failure: spider naevi, palmar erythema, white nails, gynecomastia) or morphological signs of cirrhosis (enlarged liver, nodular surface, sharp lower edge).
boolean
C0311392 (UMLS CUI [1,1])
C0023890 (UMLS CUI [1,2])
C0019209 (UMLS CUI [2])
C0231174 (UMLS CUI [3,1])
C2697585 (UMLS CUI [3,2])
C0085666 (UMLS CUI [4])
C0014745 (UMLS CUI [5])
C0423827 (UMLS CUI [6])
C0018418 (UMLS CUI [7])
C0311392 (UMLS CUI [8,1])
C0543482 (UMLS CUI [8,2])
C0023890 (UMLS CUI [8,3])
C0019209 (UMLS CUI [9])
C0205148 (UMLS CUI [10,1])
C0205297 (UMLS CUI [10,2])
C0426689 (UMLS CUI [11,1])
C0441994 (UMLS CUI [11,2])
Signs Failure Hepatocellular | Total protein measurement | Blood albumin decreased
Item
and/or biological signs of hepatocellular failure (tp<70%, low albuminemia)
boolean
C0311392 (UMLS CUI [1,1])
C0231174 (UMLS CUI [1,2])
C2697585 (UMLS CUI [1,3])
C0555903 (UMLS CUI [2])
C0853777 (UMLS CUI [3])
Other Coding | Hepatic venous pressure gradient | FibroTest Score Measurement | Other Coding | Liver Cirrhosis | Hepatitis C, Chronic | Lack Liver carcinoma Imaging | Abdominal Ultrasound | CT of abdomen | MRI of abdomen | Alpha one fetoprotein measurement
Item
and/or sinusoidal block assessed by liver venous gradient >18 mm hg in the present state of knowledge, a fibrotest value at 4 or a fibroscan value > 12,5 kpa without any other clinical or biological signs will be considered as diagnosis criteria of cirrhosis only for chronic viral c hepatitis. the lack of hcc in cirrhotic patients at inclusion will be assessed through good quality imaging examinations (abdominal us, ct scan or mri) and afp below 100 ng/ml.
boolean
C3846158 (UMLS CUI [1])
C4049263 (UMLS CUI [2])
C3642160 (UMLS CUI [3])
C3846158 (UMLS CUI [4])
C0023890 (UMLS CUI [5])
C0524910 (UMLS CUI [6])
C0332268 (UMLS CUI [7,1])
C2239176 (UMLS CUI [7,2])
C0011923 (UMLS CUI [7,3])
C2348813 (UMLS CUI [8])
C0412620 (UMLS CUI [9])
C0412693 (UMLS CUI [10])
C0201539 (UMLS CUI [11])
Age
Item
- patients under 35years old or more than 75 years of age
boolean
C0001779 (UMLS CUI [1])
Cancer Other Developmental
Item
other cancer in evolution
boolean
C1707251 (UMLS CUI [1,1])
C0458003 (UMLS CUI [1,2])
HIV Infection
Item
hiv infection
boolean
C0019693 (UMLS CUI [1])
Illness Major Inconsistent Inclusion | Mental disorders Major Inconsistent Inclusion
Item
major somatic or psychiatric illness not compatible with the inclusion in the study
boolean
C0221423 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
C0442809 (UMLS CUI [1,3])
C1512693 (UMLS CUI [1,4])
C0004936 (UMLS CUI [2,1])
C0205164 (UMLS CUI [2,2])
C0442809 (UMLS CUI [2,3])
C1512693 (UMLS CUI [2,4])
Liver carcinoma Primary Absent
Item
non hcc primary liver cancer.
boolean
C2239176 (UMLS CUI [1,1])
C0205225 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])