Liver carcinoma Biopsy | Secondary malignant neoplasm of liver Solid tumour Biopsy | Liver carcinoma Imaging | Secondary malignant neoplasm of liver Solid tumour Imaging | Neoplasms Inappropriate Radical therapy | Excision | Transplantation | Conformal Radiotherapy High dose
Item
patients with hepatocellular carcinoma or hepatic metastases from a solid malignancy, unsuitable for radical therapy (including resection, transplant, conformal high dose radiotherapy), confirmed by biopsy or imaging
boolean
C2239176 (UMLS CUI [1,1])
C0005558 (UMLS CUI [1,2])
C0494165 (UMLS CUI [2,1])
C0280100 (UMLS CUI [2,2])
C0005558 (UMLS CUI [2,3])
C2239176 (UMLS CUI [3,1])
C0011923 (UMLS CUI [3,2])
C0494165 (UMLS CUI [4,1])
C0280100 (UMLS CUI [4,2])
C0011923 (UMLS CUI [4,3])
C0027651 (UMLS CUI [5,1])
C1548788 (UMLS CUI [5,2])
C0260176 (UMLS CUI [5,3])
C0728940 (UMLS CUI [6])
C0040732 (UMLS CUI [7])
C0600521 (UMLS CUI [8,1])
C0444956 (UMLS CUI [8,2])
Symptoms Liver pain Requirement Palliative Care | Symptoms Discomfort Requirement Palliative Care | Symptoms Nausea Requirement Palliative Care | Symptoms Fatigue Requirement Palliative Care
Item
symptoms of hepatic pain, discomfort, nausea, or fatigue requiring palliation
boolean
C1457887 (UMLS CUI [1,1])
C0522067 (UMLS CUI [1,2])
C1514873 (UMLS CUI [1,3])
C0030231 (UMLS CUI [1,4])
C1457887 (UMLS CUI [2,1])
C0231218 (UMLS CUI [2,2])
C1514873 (UMLS CUI [2,3])
C0030231 (UMLS CUI [2,4])
C1457887 (UMLS CUI [3,1])
C0027497 (UMLS CUI [3,2])
C1514873 (UMLS CUI [3,3])
C0030231 (UMLS CUI [3,4])
C1457887 (UMLS CUI [4,1])
C0015672 (UMLS CUI [4,2])
C1514873 (UMLS CUI [4,3])
C0030231 (UMLS CUI [4,4])
Karnofsky Performance Status
Item
kps>60
boolean
C0206065 (UMLS CUI [1])
Life Expectancy
Item
expected survival of greater than 3 months
boolean
C0023671 (UMLS CUI [1])
Platelet Count measurement | Hemoglobin measurement | International Normalized Ratio | Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement
Item
platelet count > 25 bil/l, hemoglobin > 70 g/l, inr<3, bilirubin<100 umol/l, ast < 350 u/l or alt< 400 u/l
boolean
C0032181 (UMLS CUI [1])
C0518015 (UMLS CUI [2])
C0525032 (UMLS CUI [3])
C1278039 (UMLS CUI [4])
C0201899 (UMLS CUI [5])
C0201836 (UMLS CUI [6])
Informed Consent
Item
have signed an informed consent form approved by the research ethics board (reb) at princess margaret hospital
boolean
C0021430 (UMLS CUI [1])
Chemotherapy | Investigational New Drugs
Item
chemotherapy or novel drug within the past 2 weeks
boolean
C0392920 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
Transarterial Chemoembolization
Item
tace(transarterial chemoembolization)within the past 1 month
boolean
C3539919 (UMLS CUI [1])
Therapeutic procedure Planned Liver carcinoma | Therapeutic procedure Planned Secondary malignant neoplasm of liver | Transarterial Chemoembolization | Radiofrequency ablation | Percutaneous ethanol injection therapy
Item
plan for active treatment of the hepatocellular carcinoma or hepatic metastases, including tace or rfa or etoh injection
boolean
C0087111 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
C2239176 (UMLS CUI [1,3])
C0087111 (UMLS CUI [2,1])
C1301732 (UMLS CUI [2,2])
C0494165 (UMLS CUI [2,3])
C3539919 (UMLS CUI [3])
C0850292 (UMLS CUI [4])
C1535909 (UMLS CUI [5])