Liver disease Moderate
Item
moderate liver disease
boolean
C0023895 (UMLS CUI [1,1])
C0205081 (UMLS CUI [1,2])
Hepatitis B surface antigen positive | Hepatitis C antibody test positive
Item
test positive for hepatitis b surface antigen or hepatitis c antibody
boolean
C0149709 (UMLS CUI [1])
C1277805 (UMLS CUI [2])
Advanced Adult Hepatocellular Carcinoma Locally | Liver carcinoma unresectable | Liver carcinoma Transplantation Unsuccessful | Metastatic hepatocellular carcinoma
Item
locally advanced unresectable/untransplantable or metastatic hepatocellular carcinoma
boolean
C1706732 (UMLS CUI [1,1])
C1517927 (UMLS CUI [1,2])
C2239176 (UMLS CUI [2,1])
C1519810 (UMLS CUI [2,2])
C2239176 (UMLS CUI [3,1])
C0040733 (UMLS CUI [3,2])
C1272705 (UMLS CUI [3,3])
C0744869 (UMLS CUI [4])
Age
Item
age 18 years or older
boolean
C0001779 (UMLS CUI [1])
Pharmacotherapy Liver carcinoma | Investigational New Drugs
Item
received investigational (not yet approved by a regulatory authority) or non-investigational agent to treat hepatocellular carcinoma.
boolean
C0013216 (UMLS CUI [1,1])
C2239176 (UMLS CUI [1,2])
C0013230 (UMLS CUI [2])
Therapeutic radiology procedure
Item
received radiation therapy within 4 weeks before randomization
boolean
C1522449 (UMLS CUI [1])
Major surgery
Item
major surgery within 4 weeks before randomization
boolean
C0679637 (UMLS CUI [1])
Minor Surgical Procedures
Item
minor surgery within 2 weeks before randomization
boolean
C0038904 (UMLS CUI [1])
Systemic steroids
Item
systemic steroids within 1 week before randomization
boolean
C2825233 (UMLS CUI [1])
Hepatic Encephalopathy
Item
hepatic encephalopathy, per the investigator's evaluation
boolean
C0019151 (UMLS CUI [1])
Gastrointestinal Hemorrhage Requirement Procedural intervention
Item
history of clinically significant gastrointestinal bleeding requiring procedural intervention within 4 weeks before enrollment
boolean
C0017181 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C4035998 (UMLS CUI [1,3])
Communicable Disease Requirement Hospitalization | Communicable Disease Requirement Antibiotics
Item
history of any infection requiring hospitalization or antibiotics within 2 weeks before randomization
boolean
C0009450 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0019993 (UMLS CUI [1,3])
C0009450 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0003232 (UMLS CUI [2,3])
Metastatic malignant neoplasm to brain | Secondary malignant neoplasm of spinal cord
Item
known brain or spinal cord metastases
boolean
C0220650 (UMLS CUI [1])
C0347016 (UMLS CUI [2])
Cancer Other
Item
history of other cancers within 5 years before enrollment
boolean
C1707251 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
pregnant or breast-feeding women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
HIV Infection
Item
known hiv infection
boolean
C0019693 (UMLS CUI [1])