Liver carcinoma
Item
histologic or cytologic confirmed diagnosis of hcc.
boolean
C2239176 (UMLS CUI [1])
Liver carcinoma Advanced | Disease Inappropriate Operative Surgical Procedures | Disease Inappropriate Therapeutic procedure Locoregional | Progressive Disease Post Operative Surgical Procedures | Progressive Disease Post Therapeutic procedure Locoregional
Item
advanced hcc: disease not eligible for surgical and/or locoregional therapies or progressive disease after surgical and/or locoregional therapies
boolean
C2239176 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C0012634 (UMLS CUI [2,1])
C1548788 (UMLS CUI [2,2])
C0543467 (UMLS CUI [2,3])
C0012634 (UMLS CUI [3,1])
C1548788 (UMLS CUI [3,2])
C0087111 (UMLS CUI [3,3])
C1947913 (UMLS CUI [3,4])
C1335499 (UMLS CUI [4,1])
C0687676 (UMLS CUI [4,2])
C0543467 (UMLS CUI [4,3])
C1335499 (UMLS CUI [5,1])
C0687676 (UMLS CUI [5,2])
C0087111 (UMLS CUI [5,3])
C1947913 (UMLS CUI [5,4])
Child-Pugh Classification
Item
child-pugh class a
boolean
C2347612 (UMLS CUI [1])
ECOG performance status
Item
ecog performance status 0-1
boolean
C1520224 (UMLS CUI [1])
Hematologic function | Liver function | Renal function
Item
adequate hematologic, hepatic, and renal function
boolean
C0221130 (UMLS CUI [1])
C0232741 (UMLS CUI [2])
C0232804 (UMLS CUI [3])
Systemic Chemotherapy Liver carcinoma | Immunotherapy Liver carcinoma | Molecular Targeted Therapy Liver carcinoma
Item
prior use of any systemic anti-cancer chemotherapy, immunotherapy or molecular targeted agents for hcc
boolean
C1883256 (UMLS CUI [1,1])
C2239176 (UMLS CUI [1,2])
C0021083 (UMLS CUI [2,1])
C2239176 (UMLS CUI [2,2])
C2699893 (UMLS CUI [3,1])
C2239176 (UMLS CUI [3,2])
Heart Disease
Item
history of active cardiac disease
boolean
C0018799 (UMLS CUI [1])
Event Thrombotic | Event Embolic | Exception Liver carcinoma Thrombus
Item
thrombotic or embolic events within the past 6 months (except hcc tumor thrombus)
boolean
C0441471 (UMLS CUI [1,1])
C0087086 (UMLS CUI [1,2])
C0441471 (UMLS CUI [2,1])
C0013922 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C2239176 (UMLS CUI [3,2])
C0087086 (UMLS CUI [3,3])
Other Hemorrhage and Bleeding Adverse Event CTCAE Grades | Exception Bleeding esophageal varices | Exception Bleeding gastric varices
Item
any other hemorrhage/bleeding event >= ctcae grade 3 within 8 weeks except for esophageal or gastric varices
boolean
C1556642 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0155789 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0267209 (UMLS CUI [3,2])
Lacking Able to swallow Tablets | Malabsorption Syndrome untreated
Item
inability to swallow tablets or untreated malabsorption syndrome
boolean
C0332268 (UMLS CUI [1,1])
C2712086 (UMLS CUI [1,2])
C0039225 (UMLS CUI [1,3])
C0024523 (UMLS CUI [2,1])
C0332155 (UMLS CUI [2,2])