Hepatitis C virus genotype determination | PEGINTERFERON | Ribavirin | Unresponsive to Treatment | Recurrent disease Post Therapy cessation
Item
gt 1 previously treated with pegylated interferon & ribavirin & either non-responded or relapsed after cessation of therapy
boolean
C1533728 (UMLS CUI [1])
C0982327 (UMLS CUI [2])
C0035525 (UMLS CUI [3])
C0205269 (UMLS CUI [4])
C0277556 (UMLS CUI [5,1])
C0687676 (UMLS CUI [5,2])
C1699848 (UMLS CUI [5,3])
Insulin Resistance
Item
insulin resistance
boolean
C0021655 (UMLS CUI [1])
Compensated liver disease
Item
compensated liver disease
boolean
C3839044 (UMLS CUI [1])
White Blood Cell Count procedure
Item
wbc < 3,000/ mm3
boolean
C0023508 (UMLS CUI [1])
Neutrophil count
Item
neutrophil count < 1,500/mm3
boolean
C0200633 (UMLS CUI [1])
Platelet Count measurement
Item
platelets < 65,000/ mm3
boolean
C0032181 (UMLS CUI [1])
Albumin measurement
Item
albumin > 3 gm/dl
boolean
C0201838 (UMLS CUI [1])
Metformin | Thiazolidinediones | Washout Period Required
Item
participants on metformin or other thiazolidinedione must have 3month wash-out period
boolean
C0025598 (UMLS CUI [1])
C1257987 (UMLS CUI [2])
C1710661 (UMLS CUI [3,1])
C1514873 (UMLS CUI [3,2])
Pregnancy | Breast Feeding
Item
women who are pregnant or breast-feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Gender | Partner Pregnancy
Item
males with pregnant partners
boolean
C0079399 (UMLS CUI [1])
C0682323 (UMLS CUI [2,1])
C0032961 (UMLS CUI [2,2])
HAV Coinfection | HBV coinfection | HIV coinfection
Item
co-infection with hav, hbv, or hiv
boolean
C0376325 (UMLS CUI [1,1])
C0275524 (UMLS CUI [1,2])
C2242656 (UMLS CUI [2])
C4062778 (UMLS CUI [3])
Eye Abnormalities | Retinal Disease Severe
Item
ophthalmic abnormalities such as severe retinopathy
boolean
C0015393 (UMLS CUI [1])
C0035309 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
Thyroid dysfunction Poorly controlled
Item
poorly controlled thyroid dysfunction
boolean
C0348024 (UMLS CUI [1,1])
C3853134 (UMLS CUI [1,2])
Serum creatinine raised
Item
serum creatinine concentration > 1.5 times uln
boolean
C0700225 (UMLS CUI [1])
Mental Disorders, Severe | Neuropsychiatric syndrome Severe
Item
severe psychiatric or neuropsychiatric disorders
boolean
C4046029 (UMLS CUI [1])
C3203509 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
Alcoholic Intoxication, Chronic | Drug Dependence
Item
history of alcoholism or drug addiction 1 year prior to screening
boolean
C0001973 (UMLS CUI [1])
C1510472 (UMLS CUI [2])
Epilepsy Without Controlled medication
Item
seizure disorders not controlled with medication
boolean
C0014544 (UMLS CUI [1,1])
C0332288 (UMLS CUI [1,2])
C0742801 (UMLS CUI [1,3])
Dysfunction Cardiovascular
Item
significant cardiovascular dysfunction within the past 12 months
boolean
C3887504 (UMLS CUI [1,1])
C3887460 (UMLS CUI [1,2])
Chronic lung disease
Item
chronic pulmonary disease
boolean
C0746102 (UMLS CUI [1])