Age
Item
1. age ≥60 years
boolean
C0001779 (UMLS CUI [1])
Insurance Duration
Item
2. have been insured with hba for 12 months or longer (protocol amended to remove this criteria and allow enrollment of the general public)
boolean
C0021682 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
High risk of Heart failure
Item
3. subjects at high-risk of subsequent development of heart failure; comprising at least one of:
boolean
C0332167 (UMLS CUI [1,1])
C0018801 (UMLS CUI [1,2])
Myocardial Infarction | Left Ventricular Dysfunction Absent
Item
prior myocardial infarction (mi) without known left ventricular (lv) dysfunction
boolean
C0027051 (UMLS CUI [1])
C0242698 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Myocardial Ischemia
Item
current active ischemic heart disease
boolean
C0151744 (UMLS CUI [1])
Cerebrovascular accident
Item
prior cerebrovascular accident (cva)
boolean
C0038454 (UMLS CUI [1])
Heart valve disease | Left Ventricular Dysfunction Absent
Item
known valvular heart disease without known lv dysfunction
boolean
C0018824 (UMLS CUI [1])
C0242698 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Atrial Fibrillation
Item
atrial fibrillation
boolean
C0004238 (UMLS CUI [1])
Ventricular arrhythmia Resulting in Syncope | Ventricular arrhythmia Resulting in Presyncope
Item
ventricular arrhythmia resulting in syncope or pre-syncope (protocol amended to remove this entry criteria)
boolean
C0085612 (UMLS CUI [1,1])
C0332294 (UMLS CUI [1,2])
C0039070 (UMLS CUI [1,3])
C0085612 (UMLS CUI [2,1])
C0332294 (UMLS CUI [2,2])
C0700200 (UMLS CUI [2,3])
Hypertensive disease Treated Duration
Item
treated hypertension, of at least 2 years duration
boolean
C0020538 (UMLS CUI [1,1])
C1522326 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
Diabetes Mellitus Treated Duration
Item
treated diabetes mellitus, of at least 2 years duration
boolean
C0011849 (UMLS CUI [1,1])
C1522326 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
Estimated Glomerular Filtration Rate
Item
estimated glomerular filtration rate (egfr) <50ml/min
boolean
C3811844 (UMLS CUI [1])
Heart Failure, Systolic | Heart Failure, Diastolic
Item
1. known systolic or diastolic heart failure
boolean
C1135191 (UMLS CUI [1])
C1135196 (UMLS CUI [2])
Symptoms Suggestive of Heart failure
Item
2. symptoms suggestive of current heart failure. (protocol amended to remove this criteria)
boolean
C1457887 (UMLS CUI [1,1])
C0332299 (UMLS CUI [1,2])
C0018801 (UMLS CUI [1,3])
Left ventricular systolic dysfunction Echocardiography | Left ventricular diastolic dysfunction Echocardiography | Left ventricular systolic dysfunction Imaging | Left ventricular diastolic dysfunction Imaging
Item
3. lv systolic or diastolic dysfunction on echocardiography or other objective imaging modality.
boolean
C1277187 (UMLS CUI [1,1])
C0013516 (UMLS CUI [1,2])
C1273070 (UMLS CUI [2,1])
C0013516 (UMLS CUI [2,2])
C1277187 (UMLS CUI [3,1])
C0079595 (UMLS CUI [3,2])
C1273070 (UMLS CUI [4,1])
C0079595 (UMLS CUI [4,2])
Pharmaceutical Preparations Heart failure | Angiotensin-Converting Enzyme Inhibitors | Angiotensin II receptor antagonist | Adrenergic beta-1 Receptor Antagonists | Aldosterone Antagonists | Pharmaceutical Preparations Hypertensive disease allowied| Pharmaceutical Preparations Myocardial Infarction allowed | Pharmaceutical Preparations Diabetic Nephropathy allowed
Item
4. medications for treatment of heart failure such as ace inhibitors, angiotensin receptor blockers (arbs), beta-blockers or aldosterone antagonists. use of such medications for approved indications such as hypertension, post-mi management (without known lv dysfunction) or for diabetic nephropathy is permitted. (protocol amended to remove this criteria)
boolean
C0013227 (UMLS CUI [1,1])
C0018801 (UMLS CUI [1,2])
C0003015 (UMLS CUI [2])
C0521942 (UMLS CUI [3])
C0304516 (UMLS CUI [4])
C0002007 (UMLS CUI [5])
C0013227 (UMLS CUI [6,1])
C0020538 (UMLS CUI [6,2])
C0683607 (UMLS CUI [6,3])
C0013227 (UMLS CUI [7,1])
C0027051 (UMLS CUI [7,2])
C0683607 (UMLS CUI [7,3])
C0013227 (UMLS CUI [8,1])
C0011881 (UMLS CUI [8,2])
C0683607 (UMLS CUI [8,3])