Essential Hypertension Uncomplicated | Antihypertensive Agents Absent | Sitting diastolic blood pressure mean | Relationship Antihypertensive therapy
Item
have diagnosis of uncomplicated essential hypertension; newly diagnosed or who have not received antihypertension medication within 4 weeks of visit 1 must have an office cuff mean sitting diastolic blood pressure (msdbp) > 100 mmhg and < 110 mmhg at visit 1. if patient is receiving antihypertensive treatment, must have a cuff msdbp > 95 mmhg and < 110 mmhg at visit 1
boolean
C0085580 (UMLS CUI [1,1])
C0443334 (UMLS CUI [1,2])
C0003364 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C1319894 (UMLS CUI [3,1])
C0444504 (UMLS CUI [3,2])
C0439849 (UMLS CUI [4,1])
C0585941 (UMLS CUI [4,2])
Sitting diastolic blood pressure mean
Item
prior to randomization, all patients must have an office cuff msdbp >or= 100 mmhg and <or = 110 mmhg.
boolean
C1319894 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
Study Subject Participation Status | aliskiren
Item
participation in another aliskiren trial or previous treatment with aliskiren during last 6 months and who qualified to be randomized or enrolled into the active drug treatment period
boolean
C2348568 (UMLS CUI [1])
C1120110 (UMLS CUI [2])
Pregnancy | Breast Feeding
Item
pregnant or nursing women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Childbearing Potential Contraceptive methods Unwilling
Item
women of child bearing potential unwilling to use protocol specific contraceptive methods
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0558080 (UMLS CUI [1,3])
Sitting diastolic blood pressure mean | Sitting systolic blood pressure mean
Item
office cuff blood pressure of msdbp ≥ 112 mmhg and/or mean sitting systolic blood pressure (mssbp) ≥ 200 mmhg).
boolean
C1319894 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
C1319893 (UMLS CUI [2,1])
C0444504 (UMLS CUI [2,2])
Secondary hypertension
Item
secondary form of hypertension
boolean
C0155616 (UMLS CUI [1])
Heart failure New York Heart Association Classification
Item
history of heart failure new york heart association (nyha class ii, iii and iv)
boolean
C0018801 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Hypertensive Encephalopathy | Cerebrovascular accident | Transient Ischemic Attack | Myocardial Infarction | Coronary Artery Bypass Surgery | Percutaneous Coronary Intervention
Item
previous history of hypertensive encephalopathy or stroke, transient ischemic attack (tia), heart attack, coronary bypass surgery or any percutaneous coronary intervention (pci)
boolean
C0151620 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
C0007787 (UMLS CUI [3])
C0027051 (UMLS CUI [4])
C0010055 (UMLS CUI [5])
C1532338 (UMLS CUI [6])
Serum potassium increased
Item
elevated serum potassium (> or = 5.3 meq/l (mmol/l) at visit 1
boolean
C0553704 (UMLS CUI [1])
Insulin-Dependent Diabetes Mellitus Poorly controlled | Non-Insulin-Dependent Diabetes Mellitus Poorly controlled
Item
type 1 or type 2 diabetes mellitus not well controlled
boolean
C0011854 (UMLS CUI [1,1])
C3853134 (UMLS CUI [1,2])
C0011860 (UMLS CUI [2,1])
C3853134 (UMLS CUI [2,2])
Clinical Trial Eligibility Criteria Study Protocol
Item
other protocol-defined inclusion/exclusion criteria may apply
boolean
C1516637 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])