Gender | Age | Perimenopausal state | Postmenopausal state
Item
women age 40 and older in the peri- or postmenopausal period, as defined in soules et al. 2001
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C3839366 (UMLS CUI [3])
C0232970 (UMLS CUI [4])
Major Depressive Disorder
Item
meet criteria for major depressive disorder on the mini (mini-international neuropsychiatric interview)
boolean
C1269683 (UMLS CUI [1])
Montgomery-Asberg Depression Rating Scale Questionnaire
Item
score of 18 or greater on madrs (montgomery-asberg depression rating scale) at screening visit
boolean
C4054475 (UMLS CUI [1])
Run-in Period Placebo Response Absent
Item
do not meet criteria for placebo response during placebo run-in phase; placebo response is defined as a > 50% decrease in madrs from screening to end of placebo run-in phase
boolean
C3274438 (UMLS CUI [1,1])
C0032042 (UMLS CUI [1,2])
C1704632 (UMLS CUI [1,3])
C0332197 (UMLS CUI [1,4])
Therapeutic procedure Outpatient Base Willing
Item
willing to receive treatment on an outpatient basis
boolean
C0087111 (UMLS CUI [1,1])
C0029921 (UMLS CUI [1,2])
C1705938 (UMLS CUI [1,3])
C0600109 (UMLS CUI [1,4])
General health good
Item
presence of general good health
boolean
C1277245 (UMLS CUI [1])
Pregnancy | Pregnancy, Planned | Breast Feeding
Item
currently pregnant, trying to conceive, or breastfeeding
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
Antidepressive Agents
Item
treatment with an antidepressant medication currently or in the past 1 month
boolean
C0003289 (UMLS CUI [1])
Hormone replacement therapy
Item
treatment with hormone replacement therapy currently or in the past 1 month
boolean
C0282402 (UMLS CUI [1])
Omega-3 Fatty Acids Supplements
Item
treatment with omega-3 supplements currently or in the past 1 month
boolean
C0015689 (UMLS CUI [1,1])
C0242295 (UMLS CUI [1,2])
Contraceptives, Oral
Item
use of birth control pills currently or in the past 1 month
boolean
C0009905 (UMLS CUI [1])
Feeling suicidal
Item
presence of suicidal ideation
boolean
C0424000 (UMLS CUI [1])
Panic Disorder | Obsessive-Compulsive Disorder | Psychotic Disorders | Mania | Hypomania
Item
meet criteria for current or within the past month for panic disorder, obsessive compulsive disorder (ocd), psychosis, mania or hypomania, as assessed by the mini
boolean
C0030319 (UMLS CUI [1])
C0028768 (UMLS CUI [2])
C0033975 (UMLS CUI [3])
C0338831 (UMLS CUI [4])
C0241934 (UMLS CUI [5])
Major Depressive Disorder Unresponsive to Treatment | Antidepressive Agents Course Quantity | Depressive episode Remission Absent
Item
diagnosis of treatment resistant major depressive disorder, defined as patients who have been treated with two or more therapeutic courses of antidepressant medication without remission of symptoms for the current episode of depression, as assessed by the mini
boolean
C1269683 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
C0003289 (UMLS CUI [2,1])
C0750729 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0349217 (UMLS CUI [3,1])
C0544452 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])
Medical condition Study Subject Participation Status Unsafe
Item
any medical condition that would make participation in the study unsafe, as determined by investigator
boolean
C3843040 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C4036038 (UMLS CUI [1,3])
Allergy to fish Study Subject Participation Status At risk | Fish oils allergy Study Subject Participation Status At risk
Item
presence of a known allergy to fish or fish oil that would put participant at risk, as determined by a study investigator
boolean
C0856904 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C1444641 (UMLS CUI [1,3])
C0571871 (UMLS CUI [2,1])
C2348568 (UMLS CUI [2,2])
C1444641 (UMLS CUI [2,3])