Informed Consent
Item
signed written informed consent obtained.
boolean
C0021430 (UMLS CUI [1])
Age | Patient need for Pharmacotherapy New | Patient need for Pharmacotherapy Change New | Major Depressive Disorder
Item
males/females 20-65 years of age who require a new or a new change in their medication treatment for diagnosed major depression.
boolean
C0001779 (UMLS CUI [1])
C0686904 (UMLS CUI [2,1])
C0013216 (UMLS CUI [2,2])
C0205314 (UMLS CUI [2,3])
C0686904 (UMLS CUI [3,1])
C0013216 (UMLS CUI [3,2])
C0392747 (UMLS CUI [3,3])
C0205314 (UMLS CUI [3,4])
C1269683 (UMLS CUI [4])
Major Depressive Disorder | Single major depressive episode | Recurrent major depressive episodes
Item
a clinical diagnosis fulfilling dsm-ivtr criteria for major depressive disorder, single episode or recurrent.
boolean
C1269683 (UMLS CUI [1])
C0024517 (UMLS CUI [2])
C0154409 (UMLS CUI [3])
Hamilton Depression Rating Scale 17 Item Questionnaire
Item
17-item hamilton depression rating scale (hamd 17-item) total score at baseline of 18 or higher
boolean
C3639712 (UMLS CUI [1])
Depressive disorder | Exception Major Depressive Disorder | Exception Single major depressive episode | Exception Recurrent major depressive episodes | Chronic depression | Depressive Disorder, Treatment-Resistant
Item
clinical diagnosis of depression other than dsm-ivtr major depressive disorder (single episode/recurrent, e.g. chronic depression and/or refractory depression are excluded).
boolean
C0011581 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C1269683 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0024517 (UMLS CUI [3,2])
C1705847 (UMLS CUI [4,1])
C0154409 (UMLS CUI [4,2])
C0581391 (UMLS CUI [5])
C2063866 (UMLS CUI [6])
At risk for suicide | Potential Self-harm
Item
judged to be at significant risk for suicide or having a history suggesting significant current potential for self harm.
boolean
C0563664 (UMLS CUI [1])
C3245505 (UMLS CUI [2,1])
C0424366 (UMLS CUI [2,2])
Antidepressive Agents Other
Item
antidepressant medication (other than the index antidepressant).
boolean
C0003289 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Pregnancy | Breast Feeding | Pregnancy, Planned
Item
women who are pregnant or breast-feeding or intending to become pregnant in the next 12 months.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032992 (UMLS CUI [3])
Organ system Disease | Cardiovascular Diseases | Liver diseases | Kidney Diseases | Endocrine System Diseases | Gastrointestinal Diseases | Metabolic Diseases | Systemic disease
Item
clinically significant organ system diseases, e.g. cardiovascular, hepatic, renal, endocrine, gastrointestinal, metabolic, or other systemic diseases.
boolean
C0460002 (UMLS CUI [1,1])
C0012634 (UMLS CUI [1,2])
C0007222 (UMLS CUI [2])
C0023895 (UMLS CUI [3])
C0022658 (UMLS CUI [4])
C0014130 (UMLS CUI [5])
C0017178 (UMLS CUI [6])
C0025517 (UMLS CUI [7])
C0442893 (UMLS CUI [8])
Electroconvulsive Therapy During Observation
Item
course of electroconvulsive therapy (ect) during the observational period.
boolean
C0013806 (UMLS CUI [1,1])
C0347984 (UMLS CUI [1,2])
C1964257 (UMLS CUI [1,3])
Nervous system disorder Major | Parkinson Disease | Huntington Disease | Cerebrovascular Disorders | Cerebrovascular accident | Metabolic Diseases | Vitamin B 12 Deficiency | Autoimmune Diseases | Lupus Erythematosus, Systemic | Virus Diseases | Communicable Diseases | Hepatitis | Mononucleosis | HIV Infection | Malignant Neoplasms
Item
suffer from a major neurological condition (i.e., parkinson's disease, huntington's disease), cerebrovascular disease (i.e., stroke), metabolic conditions (i.e., vitamin b12 deficiency), autoimmune conditions (i.e., systematic lupus erythematosus), viral or other infections (i.e., hepatitis, mononucleosis, human immunodeficiency), and cancer.
boolean
C0027765 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
C0030567 (UMLS CUI [2])
C0020179 (UMLS CUI [3])
C0007820 (UMLS CUI [4])
C0038454 (UMLS CUI [5])
C0025517 (UMLS CUI [6])
C0042847 (UMLS CUI [7])
C0004364 (UMLS CUI [8])
C0024141 (UMLS CUI [9])
C0042769 (UMLS CUI [10])
C0009450 (UMLS CUI [11])
C0019158 (UMLS CUI [12])
C0021345 (UMLS CUI [13])
C0019693 (UMLS CUI [14])
C0006826 (UMLS CUI [15])
Schizophrenia | Psychotic Disorders | Schizophreniform Disorders | Schizoaffective Disorder | Delusional disorder | Psychosis, Brief Reactive | Psychotic disorder due to a general medical condition | Psychoses, Substance-Induced | Psychotic Disorders Not Otherwise Specified
Item
current diagnosis of schizophrenia or other psychotic disorders (including schizophreniform disorder, schizoaffective disorder, delusional disorder, brief psychotic disorders, psychotic disorder due to general medical condition, substance induced psychotic, psychotic disorder not otherwise specified) as defined in the dsm-iv.
boolean
C0036341 (UMLS CUI [1])
C0033975 (UMLS CUI [2])
C0036358 (UMLS CUI [3])
C0036337 (UMLS CUI [4])
C0011251 (UMLS CUI [5])
C0033958 (UMLS CUI [6])
C0748076 (UMLS CUI [7])
C0033941 (UMLS CUI [8])
C0033975 (UMLS CUI [9,1])
C1518425 (UMLS CUI [9,2])
Hypothyroidism | Hyperthyroidism | Elevated TSH
Item
(sub) clinical hypo/hyper thyroidism (e.g. elevated tsh).
boolean
C0020676 (UMLS CUI [1])
C0020550 (UMLS CUI [2])
C1855743 (UMLS CUI [3])