Informed Consent
Item
subjects who understand and sign the consent form for this study.
boolean
C0021430 (UMLS CUI [1])
Age
Item
age :18-75, males and females.
boolean
C0001779 (UMLS CUI [1])
Degenerative arthritis Kellgren-Lawrence score
Item
clinical diagnosis of degenerative arthritis by radiographic criteria of kellgren and lawrence.
boolean
C0029408 (UMLS CUI [1,1])
C3177117 (UMLS CUI [1,2])
Traditional therapy Pharmaceutical Preparations Unsuccessful | Patient need for Arthroplasty
Item
patients who can't treat with traditional medication and need a arthroplasty.
boolean
C3650840 (UMLS CUI [1,1])
C0013227 (UMLS CUI [1,2])
C1272705 (UMLS CUI [1,3])
C0686904 (UMLS CUI [2,1])
C0003893 (UMLS CUI [2,2])
Lesion size
Item
patients whose lesion is 2~6 cm2 in size.
boolean
C0449453 (UMLS CUI [1])
Pain Duration Visual Analog Pain Scale
Item
duration of pain over grade 4(11-point numeric scale) : > 4 months
boolean
C0030193 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
C0042815 (UMLS CUI [1,3])
Pregnancy | Breast Feeding | Pregnancy, Planned
Item
women who are pregnant or breast feeding or planning to become pregnant during the study.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032992 (UMLS CUI [3])
Anti-Inflammatory Agents | Herbal medicine
Item
objects who administer with a anti-inflammatory drugs contain herbal medicine within 14 days prior to inclusion in the study.
boolean
C0003209 (UMLS CUI [1])
C2240391 (UMLS CUI [2])
Substance Use Disorders | Illicit drug use Recreational | Pharmaceutical Preparations prescribed Recreational
Item
history or current evidence of alcohol or drug abuse or is a recreational user of illicit drugs or prescription medications.
boolean
C0038586 (UMLS CUI [1])
C0281875 (UMLS CUI [2,1])
C0242508 (UMLS CUI [2,2])
C0013227 (UMLS CUI [3,1])
C0278329 (UMLS CUI [3,2])
C0242508 (UMLS CUI [3,3])
Intra-Articular Injections
Item
treatment with intra-articular injection therapy within 2 months prior to screen.
boolean
C0021488 (UMLS CUI [1])
Arthropathy | Exception Degenerative arthritis | Cartilage Diseases Systemic | Cartilage Diseases Rheumatic | Cartilage Diseases inflammatory | Calcium pyrophosphate deposition disease | Hemochromatosis | Inflammatory joint disease | Avascular Necrosis of Femur Head | Osteitis Deformans | Hemophilic arthropathy | Arthritis, Infectious | Neurogenic arthropathy | Villonodular synovitis | Chondromatosis, Synovial
Item
other joint diseases except degenerative arthritis : systemic or rheumatic or inflammatory chondropathy, chondrocalcinosis, hemachromatosis, inflammatory joint disease, avascular necrosis of the femoral head, paget's disease, hemophilic arthropathy, infectional arthritis, charcot's disease, villonodular synovitis, synovial chondromatosis.
boolean
C0022408 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0029408 (UMLS CUI [2,2])
C0007302 (UMLS CUI [3,1])
C0205373 (UMLS CUI [3,2])
C0007302 (UMLS CUI [4,1])
C0035435 (UMLS CUI [4,2])
C0007302 (UMLS CUI [5,1])
C0333348 (UMLS CUI [5,2])
C0553730 (UMLS CUI [6])
C0018995 (UMLS CUI [7])
C0683381 (UMLS CUI [8])
C0410480 (UMLS CUI [9])
C0029401 (UMLS CUI [10])
C0263725 (UMLS CUI [11])
C0003869 (UMLS CUI [12])
C0003892 (UMLS CUI [13])
C0158168 (UMLS CUI [14])
C0008476 (UMLS CUI [15])
Serology positive HIV-1 | Serology positive HIV-2 | Serology positive Hepatitis B | Serology positive Hepatitis B Surface Antigens | Serology positive Hepatitis B Antibodies | Serology positive Hepatitis C | Serology positive Hepatitis C Antibodies | Serology positive Syphilis
Item
positive serology for hiv-1 orhiv-2, hepatitis b (hbsag, anti-hcv-ab), hepatitis c (anti-hcv-ab) and syphilis.
boolean
C0242089 (UMLS CUI [1,1])
C0019704 (UMLS CUI [1,2])
C0242089 (UMLS CUI [2,1])
C0019707 (UMLS CUI [2,2])
C0242089 (UMLS CUI [3,1])
C0019163 (UMLS CUI [3,2])
C0242089 (UMLS CUI [4,1])
C0019168 (UMLS CUI [4,2])
C0242089 (UMLS CUI [5,1])
C0019164 (UMLS CUI [5,2])
C0242089 (UMLS CUI [6,1])
C0019196 (UMLS CUI [6,2])
C0242089 (UMLS CUI [7,1])
C0166049 (UMLS CUI [7,2])
C0242089 (UMLS CUI [8,1])
C0039128 (UMLS CUI [8,2])
Medical condition Serious Pre-existing | Cardiovascular Diseases | Kidney Diseases | Liver diseases | Endocrine System Diseases | Malignant Neoplasms | Diabetes Mellitus
Item
serious pre-existing medical conditions like cardiovascular diseases, renal diseases, liver diseases, endocrine diseases, cancer and diabetes mellitus.
boolean
C3843040 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C2347662 (UMLS CUI [1,3])
C0007222 (UMLS CUI [2])
C0022658 (UMLS CUI [3])
C0023895 (UMLS CUI [4])
C0014130 (UMLS CUI [5])
C0006826 (UMLS CUI [6])
C0011849 (UMLS CUI [7])
Overweight | Body mass index | Obesity Grade
Item
overweight expressed as body mass index (bmi) greater than 30 (obesity grade ii). bmi estimated as mass (kg) / corporal surface (m2).
boolean
C0497406 (UMLS CUI [1])
C1305855 (UMLS CUI [2])
C0028754 (UMLS CUI [3,1])
C0441800 (UMLS CUI [3,2])
Study Subject Participation Status | Investigational New Drugs
Item
participation in another clinical trial or treatment with a different investigational product within 3 months prior to inclusion in the study.
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
Other medical condition Study Subject Participation Status Difficult
Item
other pathologic conditions or circumstances that difficult participation in the study according to medical criteria.
boolean
C3843040 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C0332218 (UMLS CUI [1,3])