Age | Good health | Medical History | Hematologic Tests | Chemistry | Complete Blood Count
Item
18 years or older and in good health as defined by an unremarkable medical history, physical and screening blood work (chemistry screen, complete blood count) within 60 days of study entry.
boolean
C0001779 (UMLS CUI [1])
C3813622 (UMLS CUI [2])
C0262926 (UMLS CUI [3])
C0018941 (UMLS CUI [4])
C0151339 (UMLS CUI [5])
C0009555 (UMLS CUI [6])
Pharmaceutical Preparations chronic Absent | Aspirin Absent | NSAIDs Related Absent
Item
no chronic medication use was allowed and participants could not have taken aspirin or related nsaids during the study or 14 days before the first dose of the study medication.
boolean
C0013227 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C0004057 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0003211 (UMLS CUI [3,1])
C0439849 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])
Risk Normal Colorectal Carcinoma | Absence First Degree Relative Colon Carcinoma | Age | Colorectal Carcinoma Absent | Absence Adenoma Size | Absence Adenoma Containing Carcinoma in Situ
Item
participants also had to be classified as being at normal-risk for developing colorectal cancer. normal-risk was defined as having: no first-degree relatives with colon cancer diagnosed before the age of 60; no personal history of colorectal cancer and no adenomas >1 cm in size or containing carcinoma in situ
boolean
C0035647 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
C0009402 (UMLS CUI [1,3])
C0332197 (UMLS CUI [2,1])
C1517194 (UMLS CUI [2,2])
C0699790 (UMLS CUI [2,3])
C0001779 (UMLS CUI [3])
C0009402 (UMLS CUI [4,1])
C0332197 (UMLS CUI [4,2])
C0332197 (UMLS CUI [5,1])
C0001430 (UMLS CUI [5,2])
C0456389 (UMLS CUI [5,3])
C0332197 (UMLS CUI [6,1])
C0001430 (UMLS CUI [6,2])
C0332256 (UMLS CUI [6,3])
C0007099 (UMLS CUI [6,4])
Exclusion Criteria
Item
exclusion criteria for both normal and increased risk for colorectal cancer:
boolean
C0680251 (UMLS CUI [1])
Peptic Ulcer | Gastrointestinal Hemorrhage Due to Gastric ulcer | Gastrointestinal Hemorrhage Due to Duodenal Ulcer | Gastrin secreting tumor
Item
1. a history of peptic ulcer disease, gastrointestinal bleeding from gastric or duodenal ulcers, or gastrin secreting tumors;
boolean
C0030920 (UMLS CUI [1])
C0017181 (UMLS CUI [2,1])
C0678226 (UMLS CUI [2,2])
C0038358 (UMLS CUI [2,3])
C0017181 (UMLS CUI [3,1])
C0678226 (UMLS CUI [3,2])
C0013295 (UMLS CUI [3,3])
C0017150 (UMLS CUI [4])
Pregnancy | Breast Feeding
Item
2. pregnant or lactating women;
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Cardiovascular Disease
Item
3. history of cardiovascular disease;
boolean
C0007222 (UMLS CUI [1])
Lactose Intolerance
Item
4. lactose intolerance;
boolean
C0022951 (UMLS CUI [1])
Hypersensitivity Ginger
Item
5. or an allergy to ginger
boolean
C0020517 (UMLS CUI [1,1])
C0162751 (UMLS CUI [1,2])
Colorectal Carcinoma Familial
Item
6. a history of familial colorectal cancer syndromes;.
boolean
C0009402 (UMLS CUI [1,1])
C0241888 (UMLS CUI [1,2])
Inclusion criteria Risk Increased
Item
inclusion criteria increased risk:
boolean
C1512693 (UMLS CUI [1,1])
C0035647 (UMLS CUI [1,2])
C0205217 (UMLS CUI [1,3])
Age | Good health | Medical History | Hematologic Tests | Chemistry | Complete Blood Count
Item
18 years or older and in good health as defined by an unremarkable medical history, physical and screening blood work (chemistry screen, complete blood count) within 60 days of study entry.
boolean
C0001779 (UMLS CUI [1])
C3813622 (UMLS CUI [2])
C0262926 (UMLS CUI [3])
C0018941 (UMLS CUI [4])
C0151339 (UMLS CUI [5])
C0009555 (UMLS CUI [6])
Pharmaceutical Preparations chronic Absent | Aspirin Absent | NSAIDs Related Absent
Item
no chronic medication use was allowed and participants could not have taken aspirin or related nsaids during the study or 14 days before the first dose of the study medication.
boolean
C0013227 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C0004057 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0003211 (UMLS CUI [3,1])
C0439849 (UMLS CUI [3,2])
C0332197 (UMLS CUI [3,3])
Risk Increased Colorectal Carcinoma | First Degree Relative Colon Carcinoma | Age | Colorectal Carcinoma Early stage | Absence Adenoma Size | Absence Adenoma Containing Carcinoma in Situ
Item
participants also had to be classified as being at increased-risk for developing colorectal cancer. increased-risk is defined as having at least one of the following: a first-degree relatives with colon cancer diagnosed before the age of 60; a personal history of early stage colorectal cancer and/or no adenomas >1 cm in size or containing carcinoma in situ
boolean
C0035647 (UMLS CUI [1,1])
C0205217 (UMLS CUI [1,2])
C0009402 (UMLS CUI [1,3])
C1517194 (UMLS CUI [2,1])
C0699790 (UMLS CUI [2,2])
C0001779 (UMLS CUI [3])
C0009402 (UMLS CUI [4,1])
C2363430 (UMLS CUI [4,2])
C0332197 (UMLS CUI [5,1])
C0001430 (UMLS CUI [5,2])
C0456389 (UMLS CUI [5,3])
C0332197 (UMLS CUI [6,1])
C0001430 (UMLS CUI [6,2])
C0332256 (UMLS CUI [6,3])
C0007099 (UMLS CUI [6,4])