Hematologic Neoplasm
Item
diagnosis of a hematological malignancy
boolean
C0376545 (UMLS CUI [1])
Allogeneic Hematopoietic Stem Cell Transplantation Scheduled
Item
candidate for an allogeneic hematopoietic stem cell transplantation
boolean
C1705576 (UMLS CUI [1,1])
C0205539 (UMLS CUI [1,2])
Donor Relative HLA Antigens Match Available
Item
available hla-identical related donor
boolean
C0040288 (UMLS CUI [1,1])
C0080103 (UMLS CUI [1,2])
C0019721 (UMLS CUI [1,3])
C1708943 (UMLS CUI [1,4])
C0470187 (UMLS CUI [1,5])
Client Characteristics
Item
patient characteristics:
boolean
C0815172 (UMLS CUI [1])
WHO performance status scale | Karnofsky Performance Status
Item
who performance status (ps) 0-1 or karnofsky ps 70-100%
boolean
C1298650 (UMLS CUI [1])
C0206065 (UMLS CUI [2])
Life Expectancy
Item
life expectancy > 6 months
boolean
C0023671 (UMLS CUI [1])
Left ventricular ejection fraction
Item
lvef ≥ 40%
boolean
C0428772 (UMLS CUI [1])
Carbon Monoxide Diffusing Capability Test
Item
dlco ≥ 50%
boolean
C1516251 (UMLS CUI [1])
Creatinine clearance measurement
Item
creatinine clearance ≥ 30 ml/min
boolean
C0373595 (UMLS CUI [1])
Transaminases | Serum total bilirubin measurement
Item
transaminases and/or bilirubin ≤ 2 times upper limit of normal (uln)
boolean
C0002594 (UMLS CUI [1])
C1278039 (UMLS CUI [2])
Exclusion Cancer Other | Exception Basal cell carcinoma | Exception Carcinoma in situ of uterine cervix
Item
no other cancer within the past 5 years, except for basal cell carcinoma of the skin or carcinoma in situ of the cervix
boolean
C2828389 (UMLS CUI [1,1])
C1707251 (UMLS CUI [1,2])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0851140 (UMLS CUI [3,2])
Exclusion | Human t-cell leukemia virus 1 Positive
Item
no human t-cell leukemia virus type 1 positivity
boolean
C2828389 (UMLS CUI [1,1])
C0020094 (UMLS CUI [1,2])
C1514241 (UMLS CUI [1,3])
Exclusion HIV Seropositivity
Item
no hiv positivity
boolean
C2828389 (UMLS CUI [1,1])
C0019699 (UMLS CUI [1,2])
Exclusion Criteria | Bacterial Infection Uncontrolled | Virus Disease Uncontrolled | Mycoses Uncontrolled
Item
no uncontrolled bacterial, viral, or fungal infection
boolean
C0680251 (UMLS CUI [1])
C0004623 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
C0042769 (UMLS CUI [3,1])
C0205318 (UMLS CUI [3,2])
C0026946 (UMLS CUI [4,1])
C0205318 (UMLS CUI [4,2])
Exclusion | Medical contraindication Investigational New Drugs
Item
no contraindications to the study drugs
boolean
C2828389 (UMLS CUI [1])
C1301624 (UMLS CUI [2,1])
C0013230 (UMLS CUI [2,2])
Exclusion | Comorbidity Serious Uncontrolled
Item
no concurrent serious and uncontrolled disease
boolean
C2828389 (UMLS CUI [1])
C0009488 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C0205318 (UMLS CUI [2,3])
Therapeutic procedure
Item
prior concurrent therapy:
boolean
C0087111 (UMLS CUI [1])
Study Subject Participation Status
Item
at least 1 month since prior participation in a clinical trial
boolean
C2348568 (UMLS CUI [1])