Healthy Volunteers
Item
inclusion criteria for healthy volunteers
boolean
C1708335 (UMLS CUI [1])
Gender | Postmenopausal state | Age
Item
males and post-menopausal females, between the age of 50 -80.
boolean
C0079399 (UMLS CUI [1])
C0232970 (UMLS CUI [2])
C0001779 (UMLS CUI [3])
Low 25-OH-vitamin D level
Item
vitamin d 25-oh level less than 20 ng/ml
boolean
C3279609 (UMLS CUI [1])
Volunteers | Renal function Level Medium
Item
inclusion criteria for medium-level kidney function volunteers
boolean
C0020155 (UMLS CUI [1])
C0232804 (UMLS CUI [2,1])
C0441889 (UMLS CUI [2,2])
C0439536 (UMLS CUI [2,3])
Gender | Postmenopausal state | Age
Item
males and post-menopausal females, between the age of 50 -80.
boolean
C0079399 (UMLS CUI [1])
C0232970 (UMLS CUI [2])
C0001779 (UMLS CUI [3])
Chronic Kidney Disease Stage
Item
chronic kidney disease stage 3
boolean
C1561643 (UMLS CUI [1,1])
C2074731 (UMLS CUI [1,2])
Low 25-OH-vitamin D level
Item
vitamin d 25-oh level less than 20 ng/ml
boolean
C3279609 (UMLS CUI [1])
Serum calcium measurement
Item
serum calcium level >10.5 mg/dl
boolean
C0728876 (UMLS CUI [1])
Serum phosphorus measurement
Item
serum phosphorus level > 5.5 mg/dl
boolean
C2229833 (UMLS CUI [1])
Serum parathyroid hormone measurement
Item
serum pth level < 35 pg/ml
boolean
C0428408 (UMLS CUI [1])
Communicable Disease | HIV Infection | Hepatitis B | Hepatitis C
Item
active infection including hiv, hepatitis b or c
boolean
C0009450 (UMLS CUI [1])
C0019693 (UMLS CUI [2])
C0019163 (UMLS CUI [3])
C0019196 (UMLS CUI [4])
Recent infection
Item
history of recent acute infection ( within 1 month)
boolean
C2169571 (UMLS CUI [1])
Gastrointestinal Disease Resulting in Gastrointestinal dysfunction | Gastrointestinal Disease Resulting in Malabsorption
Item
gastrointestinal disease resulting in significant gi dysfunction or malabsorption
boolean
C0017178 (UMLS CUI [1,1])
C0332294 (UMLS CUI [1,2])
C0679407 (UMLS CUI [1,3])
C0017178 (UMLS CUI [2,1])
C0332294 (UMLS CUI [2,2])
C3714745 (UMLS CUI [2,3])
Hemoglobin measurement
Item
hgb< 10 g/dl
boolean
C0518015 (UMLS CUI [1])
Coumadin
Item
current use of coumadin
boolean
C0699129 (UMLS CUI [1])
Vitamin D IU/day
Item
current use of vitamin d >400 iu/day
boolean
C0042866 (UMLS CUI [1,1])
C0439465 (UMLS CUI [1,2])
Systemic steroids | Immunosuppressive Agents
Item
current use of systemic steroids or other immunosuppressants
boolean
C2825233 (UMLS CUI [1])
C0021081 (UMLS CUI [2])
Malignant Neoplasms | Remission Lacking
Item
history of malignancy not in remission (>6 months)
boolean
C0006826 (UMLS CUI [1])
C0544452 (UMLS CUI [2,1])
C0332268 (UMLS CUI [2,2])
Alcohol abuse | Illicit drug use
Item
history of current ethanol abuse or illicit drug use
boolean
C0085762 (UMLS CUI [1])
C0281875 (UMLS CUI [2])
Emotional disorder
Item
history of significant emotional disorder within the past 5 years
boolean
C0233459 (UMLS CUI [1])
Study Subject Participation Status | Investigational New Drugs
Item
participation in an investigational drug study within one month of screening
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
Condition Study Subject Participation Status Excluded
Item
have any other condition, which in the opinion of the investigator, should prohibit the participation in the study
boolean
C0348080 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C2828389 (UMLS CUI [1,3])