Hepatitis C | Hepatitis C antibody positive | Hepatitis C virus RNA Detectable Polymerase Chain Reaction
Item
hcv infection confirmed on a positive test for anti-hcv antibody and hcv rna detectable in serum by polymerase chain reaction.
boolean
C0019196 (UMLS CUI [1])
C0281863 (UMLS CUI [2])
C0369335 (UMLS CUI [3,1])
C3830527 (UMLS CUI [3,2])
C0032520 (UMLS CUI [3,3])
Hepatitis, Chronic
Item
histological diagnosis of chronic hepatitis.
boolean
C0019189 (UMLS CUI [1])
Pegylated interferon alfa Unresponsive to Treatment | Ribavirin Unresponsive to Treatment | Medical contraindication Antiviral Therapy
Item
patients who were non-responders to previous treatment with pegylated interferon and ribavirin or who had contraindicated the antiviral treatment.
boolean
C0907160 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
C0035525 (UMLS CUI [2,1])
C0205269 (UMLS CUI [2,2])
C1301624 (UMLS CUI [3,1])
C0280274 (UMLS CUI [3,2])
Age
Item
age between 18 and 65 years.
boolean
C0001779 (UMLS CUI [1])
Informed Consent
Item
ability to provide informed consent.
boolean
C0021430 (UMLS CUI [1])
Alcohol consumption Significant Absent | Alcohol consumption U/week
Item
absence of significant alcohol ingestion (weekly ethanol consumption of less than 40 g)
boolean
C0001948 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C0001948 (UMLS CUI [2,1])
C0560588 (UMLS CUI [2,2])
Liver diseases | Viral hepatitis | Hepatitis, Autoimmune | Drug-Induced Liver Disease | Nonalcoholic Steatohepatitis | Liver diseases Metabolic | Liver diseases Hereditary | alpha 1-Antitrypsin Deficiency
Item
presence of other form of liver diseases (viral or autoimmune hepatitis, drug-induced liver disease, nonalcoholic steatohepatitis, metabolic and hereditary liver disease and α-1 antitrypsin deficiency).
boolean
C0023895 (UMLS CUI [1])
C0042721 (UMLS CUI [2])
C0241910 (UMLS CUI [3])
C0860207 (UMLS CUI [4])
C3241937 (UMLS CUI [5])
C0023895 (UMLS CUI [6,1])
C0311400 (UMLS CUI [6,2])
C0023895 (UMLS CUI [7,1])
C0439660 (UMLS CUI [7,2])
C0221757 (UMLS CUI [8])
Pregnancy | Breast Feeding
Item
pregnancy or lactation.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Decompensated cirrhosis
Item
decompensated cirrhosis.
boolean
C1619727 (UMLS CUI [1])
Malignant neoplasm of liver Evidence Absent | Malignant neoplasm of liver Absent Ultrasonography | Alpha fetoprotein measurement
Item
absence of clinical and ultrasonographic evidence of liver cancer, with α-fetoprotein levels ≤ 200 ng/ml.
boolean
C0345904 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
C0345904 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0041618 (UMLS CUI [2,3])
C0201539 (UMLS CUI [3])
Study Subject Participation Status Refusal to Participate
Item
refusal to participate in the study.
boolean
C2348568 (UMLS CUI [1,1])
C1136454 (UMLS CUI [1,2])
Comorbidity Reduced life expectancy
Item
concomitant disease with reduced life expectancy.
boolean
C0009488 (UMLS CUI [1,1])
C1858274 (UMLS CUI [1,2])
Mental condition Severe
Item
severe psychiatric conditions.
boolean
C3840291 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
Drug Dependence
Item
drug dependence.
boolean
C1510472 (UMLS CUI [1])
Hepatitis A Coinfection | HBV coinfection | HIV coinfection
Item
co-infection with hepatitis a or b or hiv.
boolean
C0019159 (UMLS CUI [1,1])
C0275524 (UMLS CUI [1,2])
C2242656 (UMLS CUI [2])
C4062778 (UMLS CUI [3])
Pregnancy
Item
pregnancy.
boolean
C0032961 (UMLS CUI [1])