Adult | Outpatients | Age
Item
male or female, adult, out-patients aged between 18 and 85 years
boolean
C0001675 (UMLS CUI [1])
C0029921 (UMLS CUI [2])
C0001779 (UMLS CUI [3])
Hospital admission | Discharge diagnosis Congestive heart failure
Item
patients with documented hospital admission within the previous 3 months before randomization with discharge diagnosis of chf
boolean
C0184666 (UMLS CUI [1])
C1555319 (UMLS CUI [2,1])
C0018802 (UMLS CUI [2,2])
New York Heart Association Classification | Left ventricular ejection fraction
Item
patients with functional nyha class ii-iv with lvef < 40% assessed within the last 3 months
boolean
C1275491 (UMLS CUI [1])
C0428772 (UMLS CUI [2])
Brain natriuretic peptide measurement | N-Terminal ProB-type Natriuretic Peptide Measurement
Item
patients with blood bnp levels > 400 pg/ml or nt-probnp levels > 1500 pg/ml
boolean
C1095989 (UMLS CUI [1])
C3272900 (UMLS CUI [2])
Congestive heart failure Due to Myocardial Ischemia | Congestive heart failure Due to Idiopathic Dilated Cardiomyopathy | Congestive heart failure Due to Mitral Valve Insufficiency | Congestive heart failure Due to Aortic Valve Insufficiency | Congestive heart failure Due to Hypertensive disease
Item
patients with chf due to ischemic heart disease, idiopathic dilated cardiomyopathy (idc), mitral or aortic insufficiency or hypertension
boolean
C0018802 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0151744 (UMLS CUI [1,3])
C0018802 (UMLS CUI [2,1])
C0678226 (UMLS CUI [2,2])
C1449563 (UMLS CUI [2,3])
C0018802 (UMLS CUI [3,1])
C0678226 (UMLS CUI [3,2])
C0026266 (UMLS CUI [3,3])
C0018802 (UMLS CUI [4,1])
C0678226 (UMLS CUI [4,2])
C0003504 (UMLS CUI [4,3])
C0018802 (UMLS CUI [5,1])
C0678226 (UMLS CUI [5,2])
C0020538 (UMLS CUI [5,3])
Diuretics Stable | Angiotensin-Converting Enzyme Inhibitors Stable | Adrenergic beta-1 Receptor Antagonists Stable | Aldosterone Antagonists Stable | Exception Medical contraindication | Exception Intolerance
Item
patients with stable conventional treatment with diuretics, acei and/or beta-blockers and/or aldosterone antagonists for at least 2 months prior to randomisation, unless documented contraindication or intolerance
boolean
C0012798 (UMLS CUI [1,1])
C0205360 (UMLS CUI [1,2])
C0003015 (UMLS CUI [2,1])
C0205360 (UMLS CUI [2,2])
C0304516 (UMLS CUI [3,1])
C0205360 (UMLS CUI [3,2])
C0002007 (UMLS CUI [4,1])
C0205360 (UMLS CUI [4,2])
C1705847 (UMLS CUI [5,1])
C1301624 (UMLS CUI [5,2])
C1705847 (UMLS CUI [6,1])
C1744706 (UMLS CUI [6,2])
Pregnancy | Pregnancy, Planned | Breast Feeding | Childbearing Potential Contraceptive methods Lacking
Item
females who are pregnant or plan a pregnancy during the time of the trial, are nursing or are of childbearing potential and not using acceptable methods of contraception. if a female becomes pregnant during the study, she has to be withdrawn immediately
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
C3831118 (UMLS CUI [4,1])
C0700589 (UMLS CUI [4,2])
C0332268 (UMLS CUI [4,3])
Hospitalization Due to Heart Failure
Item
patients with current hospitalisation due to heart failure
boolean
C3898876 (UMLS CUI [1])
Cerebrovascular accident | Transient Ischemic Attack
Item
patients with stroke or transient ischemic attack (tia) within the last 3 months
boolean
C0038454 (UMLS CUI [1])
C0007787 (UMLS CUI [2])
Acute Coronary Syndrome | Myocardial Infarction | Coronary Artery Bypass | Angioplasty
Item
patients with acute coronary syndrome, myocardial infarction, coronary artery bypass or angioplasty within 3 months
boolean
C0948089 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
C0010055 (UMLS CUI [3])
C0162577 (UMLS CUI [4])
Cardiac Surgery Planned | Cardiac Revascularization Planned | Cardiac Resynchronization Therapy Planned
Item
planned cardiac surgery, revascularization or resynchronization within the study period
boolean
C0018821 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
C0027056 (UMLS CUI [2,1])
C1301732 (UMLS CUI [2,2])
C1167956 (UMLS CUI [3,1])
C1301732 (UMLS CUI [3,2])
Valvular disease Operable | Obstructive Cardiomyopathy
Item
patients with operable valvular disease or significant obstructive cardiomyopathy
boolean
C3258293 (UMLS CUI [1,1])
C0205188 (UMLS CUI [1,2])
C0007194 (UMLS CUI [2])
Bradycardia | Heart rate
Item
patients with bradycardia [heart rate (hr) < 50 bpm]
boolean
C0428977 (UMLS CUI [1])
C0018810 (UMLS CUI [2])
Hypotension | Systolic Pressure
Item
patients with hypotension [systolic blood pressure (sbp) < 90 mmhg]
boolean
C0020649 (UMLS CUI [1])
C0871470 (UMLS CUI [2])
Lung Diseases, Obstructive
Item
patients with obstructive pneumopathy
boolean
C0600260 (UMLS CUI [1])
Kidney Failure | Creatinine measurement
Item
patients with clinical significant renal failure (creatininemia > 200 micromol/l)
boolean
C0035078 (UMLS CUI [1])
C0201975 (UMLS CUI [2])