Breast Carcinoma TNM Breast tumor staging | Chemotherapy failed | Chemotherapy Refused
Item
subjects diagnosed with stage iiib or iv breast cancer who have failed with or refuse to receive standard chemotherapies
boolean
C0678222 (UMLS CUI [1,1])
C0474926 (UMLS CUI [1,2])
C0392920 (UMLS CUI [2,1])
C0231175 (UMLS CUI [2,2])
C0392920 (UMLS CUI [3,1])
C1705116 (UMLS CUI [3,2])
Receptor expression Estrogen receptor negative | Receptor expression Progesterone receptor negative | Receptor expression Estrogen receptor positive | Receptor expression Progesterone receptor positive | Hormone Therapy failed | Hormone Therapy Refused
Item
subjects with the expression of er/pr negative; or positive er/pr expression but have failed with or refuse to receive hormonal therapy
boolean
C0597360 (UMLS CUI [1,1])
C0279756 (UMLS CUI [1,2])
C0597360 (UMLS CUI [2,1])
C0279766 (UMLS CUI [2,2])
C0597360 (UMLS CUI [3,1])
C0279754 (UMLS CUI [3,2])
C0597360 (UMLS CUI [4,1])
C0279759 (UMLS CUI [4,2])
C0279025 (UMLS CUI [5,1])
C0231175 (UMLS CUI [5,2])
C0279025 (UMLS CUI [6,1])
C1705116 (UMLS CUI [6,2])
Gene Expression HER2/Neu Positive | Gene Expression HER2/Neu Negative
Item
either + or - expression of her-2/neu gene
boolean
C0017262 (UMLS CUI [1,1])
C2348909 (UMLS CUI [1,2])
C0017262 (UMLS CUI [2,1])
C2348908 (UMLS CUI [2,2])
ECOG performance status
Item
ecog status = 0-2
boolean
C1520224 (UMLS CUI [1])
Metastatic Lesion Evaluable Quantity | Metastatic Lesion Measurable Quantity
Item
at least have 1 evaluable and measurable metastatic lesion as defined by recist criteria
boolean
C1513183 (UMLS CUI [1,1])
C1516986 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C1513183 (UMLS CUI [2,1])
C1513040 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
Hematologic function | Liver function | Renal function
Item
adequate haematological, liver, and renal function
boolean
C0221130 (UMLS CUI [1])
C0232741 (UMLS CUI [2])
C0232804 (UMLS CUI [3])
Prior Chemotherapy Elapsed Time | Prior radiation therapy Elapsed Time | Biological treatment Previous Elapsed Time | Prior Hormone Therapy Elapsed Time
Item
at least 3 weeks has elapsed since prior chemotherapy, radiotherapy, biological/hormonal therapy
boolean
C1514457 (UMLS CUI [1,1])
C2826303 (UMLS CUI [1,2])
C0279134 (UMLS CUI [2,1])
C2826303 (UMLS CUI [2,2])
C1531518 (UMLS CUI [3,1])
C0205156 (UMLS CUI [3,2])
C2826303 (UMLS CUI [3,3])
C1514460 (UMLS CUI [4,1])
C2826303 (UMLS CUI [4,2])
Surgical biopsy Elapsed Time | Major surgery Elapsed Time
Item
at least 4 weeks has elapsed since surgical biopsy / major surgery
boolean
C0565118 (UMLS CUI [1,1])
C2826303 (UMLS CUI [1,2])
C0679637 (UMLS CUI [2,1])
C2826303 (UMLS CUI [2,2])
Hypersensitivity Investigational New Drugs
Item
allergic to the trial product
boolean
C0020517 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
Medical condition Interferes with Study Subject Participation Status | Medical condition Interferes with Clinical Trial Evaluation | Communicable Diseases | Illness Uncontrolled
Item
any other disease state, including infections or uncontrolled illnesses that could interfere with trial participation or trial evaluation
boolean
C3843040 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C2348568 (UMLS CUI [1,3])
C3843040 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0008976 (UMLS CUI [2,3])
C1261322 (UMLS CUI [2,4])
C0009450 (UMLS CUI [3])
C0221423 (UMLS CUI [4,1])
C0205318 (UMLS CUI [4,2])
Herbal medicine Suspected Effect Malignant Neoplasms | Food Supplements Suspected Effect Malignant Neoplasms
Item
concurrent herbal (alternative) medicine or food supplements suspected to have effect on cancer disease
boolean
C2240391 (UMLS CUI [1,1])
C0750491 (UMLS CUI [1,2])
C1280500 (UMLS CUI [1,3])
C0006826 (UMLS CUI [1,4])
C0242295 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
C1280500 (UMLS CUI [2,3])
C0006826 (UMLS CUI [2,4])