disease characteristic
Item
disease characteristics:
boolean
C0599878 (UMLS CUI [1])
Breast adenocarcinoma Invasive Primary
Item
histologically confirmed primary infiltrating adenocarcinoma of the breast
boolean
C0858252 (UMLS CUI [1,1])
C0205281 (UMLS CUI [1,2])
C0205225 (UMLS CUI [1,3])
Core needle biopsy | Incisional biopsy | Operative Surgical Procedures
Item
confirmed by core needle biopsy or incisional biopsy or surgery
boolean
C1318309 (UMLS CUI [1])
C0184922 (UMLS CUI [2])
C0543467 (UMLS CUI [3])
Cardiotoxicity CTCAE Grades | Chemotherapy | Anthracyclines
Item
experienced grade 1 cardiac toxicity during prior anthracycline-based chemotherapy
boolean
C0876994 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
C0392920 (UMLS CUI [2])
C0282564 (UMLS CUI [3])
Chemotherapy cycle Quantity | Anthracyclines
Item
at least 2 cycles same anthracycline based chemotherapy are needed
boolean
C1302181 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0282564 (UMLS CUI [2])
Epinephrine Dosage Accumulation
Item
accumulated dose of epi ≥1000mg/m2,adm≥550mg/m2
boolean
C0014563 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C4055506 (UMLS CUI [1,3])
Risk factors | Cardiovascular Disease Uncontrolled | Cardiovascular Disease Severe | Myocardial Infarction | Pharmacotherapy Congestive heart failure | Uncontrolled hypertension | Irradiation of heart
Item
with the following risk factors: uncontrolled or severe cardiovascular disease (e.g., myocardial infarction within the past 6 months, congestive heart failure treated with medications, or uncontrolled hypertension); prior or concurrent radiation to heart
boolean
C0035648 (UMLS CUI [1])
C0007222 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
C0007222 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0027051 (UMLS CUI [4])
C0013216 (UMLS CUI [5,1])
C0018802 (UMLS CUI [5,2])
C1868885 (UMLS CUI [6])
C2169053 (UMLS CUI [7])
Pregnancy | Breast Feeding
Item
pregnant or nursing
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Cancer Other | Exception Skin carcinoma
Item
other currently active malignancy except nonmelanoma skin cancer
boolean
C1707251 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0699893 (UMLS CUI [2,2])
Bleeding uncontrolled | Hemorrhage Severe | Diarrhea | Intestinal Obstruction
Item
uncontrolled or severe bleeding,diarrhea,intestinal obstruction
boolean
C3842135 (UMLS CUI [1])
C0019080 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C0011991 (UMLS CUI [3])
C0021843 (UMLS CUI [4])
Cardiotoxicity CTCAE Grades
Item
grade 2 or more cardiac toxicity (ctc ae3.0)
boolean
C0876994 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])