Marginal Zone B-Cell Lymphoma
Item
histologically confirmed marginal zone b-cell lymphomas
boolean
C1367654 (UMLS CUI [1])
Neoadjuvant Therapy | Stable Disease failed | Recurrent disease
Item
failure to achieve a clinical benefit (≥sd) with the initial treatment, or recurrent disease
boolean
C0600558 (UMLS CUI [1])
C0677946 (UMLS CUI [2,1])
C0231175 (UMLS CUI [2,2])
C0277556 (UMLS CUI [3])
ECOG performance status
Item
performance status (ecog) ≤2
boolean
C1520224 (UMLS CUI [1])
Age
Item
age ≥ 20
boolean
C0001779 (UMLS CUI [1])
Measurable Disease 2-Dimensional Quantity CT | Measurable Disease 2-Dimensional Quantity Spiral CT | Skin lesion Photograph | Measurable Disease Physical Examination
Item
at least one or more bi-dimensionally measurable lesion(s) defined as; ≥2 cm by conventional ct or ≥ 1 cm by spiral ct or skin lesion (photographs should be taken) or measurable lesion by physical examination
boolean
C1513041 (UMLS CUI [1,1])
C1705052 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0040405 (UMLS CUI [1,4])
C1513041 (UMLS CUI [2,1])
C1705052 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0860888 (UMLS CUI [2,4])
C0037284 (UMLS CUI [3,1])
C0441468 (UMLS CUI [3,2])
C1513041 (UMLS CUI [4,1])
C0031809 (UMLS CUI [4,2])
Renal function | Creatinine measurement, serum | Creatinine clearance measurement
Item
adequate kidney functions defined as; cr < 2.0 mg% or ccr > 60 ml/min
boolean
C0232804 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
C0373595 (UMLS CUI [3])
Liver function | Transaminases | Serum total bilirubin measurement
Item
adequate liver functions defined as; transaminases < 3 x upper normal values; bilirubin < 2 mg%
boolean
C0232741 (UMLS CUI [1])
C0002594 (UMLS CUI [2])
C1278039 (UMLS CUI [3])
Bone Marrow function | Absolute neutrophil count | Platelet Count measurement
Item
adequate bone marrow functions defined as; anc > 1500/㎕, platelet > 75000/㎕
boolean
C0005953 (UMLS CUI [1,1])
C0031843 (UMLS CUI [1,2])
C0948762 (UMLS CUI [2])
C0032181 (UMLS CUI [3])
Ann Arbor lymphoma staging system
Item
ann arbor stage iii or iv
boolean
C0432516 (UMLS CUI [1])
Ann Arbor lymphoma staging system | Stage Inappropriate Therapeutic radiology procedure | Stage Inappropriate Surgical approach | Lesion of lung multiple | Involvement with Colon multiple | Abdominal lymph nodes Remote Involvement with Stomach
Item
ann arbor stage i or ii, which is not adequate for rt or surgical approach (e.g. multiple lung lesions, multiple colon involvement, remote abdominal ln with stomach involvement)
boolean
C0432516 (UMLS CUI [1])
C1300072 (UMLS CUI [2,1])
C1548788 (UMLS CUI [2,2])
C1522449 (UMLS CUI [2,3])
C1300072 (UMLS CUI [3,1])
C1548788 (UMLS CUI [3,2])
C0449446 (UMLS CUI [3,3])
C0577916 (UMLS CUI [4,1])
C0439064 (UMLS CUI [4,2])
C1314939 (UMLS CUI [5,1])
C1281569 (UMLS CUI [5,2])
C0439064 (UMLS CUI [5,3])
C0588058 (UMLS CUI [6,1])
C0205157 (UMLS CUI [6,2])
C1314939 (UMLS CUI [6,3])
C0038351 (UMLS CUI [6,4])
Informed Consent
Item
written informed consent approved by institutional review board or ethic committee
boolean
C0021430 (UMLS CUI [1])
Malignant Neoplasms | Exception Basal cell carcinoma | Exception Carcinoma in situ of uterine cervix
Item
any other malignancies within the past 5 years except skin basal cell ca or cis of cervix
boolean
C0006826 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0007117 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0851140 (UMLS CUI [3,2])
Comorbidity Serious
Item
serious co-morbid diseases
boolean
C0009488 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
Pregnancy | Breast Feeding
Item
pregnancy or breast feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Hypersensitivity Investigational New Drugs
Item
previous history of drug allergy to one of the drugs in the study regimen
boolean
C0020517 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
Investigational New Drugs | Chemotherapy | Hormone Therapy | Immunotherapy
Item
during this study duration, patients who take other clinical trial medication, chemotherapy, hormonal therapy, or immunotherapy
boolean
C0013230 (UMLS CUI [1])
C0392920 (UMLS CUI [2])
C0279025 (UMLS CUI [3])
C0021083 (UMLS CUI [4])