Safety Lab - GSK Study: GW679769 administered alone vs. with dexamethasone - Evaluation of safety, tolerability and pharmacokinetics NCT00291876

Hematology
Description

Hematology

Alias
UMLS CUI-1
C0018941
WBC
Description

Leukocytes (WBC)

Data type

float

Measurement units
  • 10^9/L
Alias
UMLS CUI [1]
C0023508
10^9/L
Red cells
Description

Red Blood Count

Data type

float

Measurement units
  • 10^12/ L
Alias
UMLS CUI [1]
C1287262
10^12/ L
Hematocrit (PCV)
Description

Hematocrit

Data type

float

Measurement units
  • %
Alias
UMLS CUI [1]
C0518014
%
Mean cell volume
Description

Mean cell volume

Data type

integer

Measurement units
  • FL
Alias
UMLS CUI [1]
C0524587
FL
Mean cell hemoglobin (MCH)
Description

Mean cell hemoglobin (MCH)

Data type

float

Measurement units
  • pg
Alias
UMLS CUI [1]
C0369183
pg
MCHC
Description

MCHC

Data type

float

Measurement units
  • g/dl
Alias
UMLS CUI [1]
C0474535
g/dl
RBC distribution width
Description

rdw

Data type

float

Measurement units
  • %
Alias
UMLS CUI [1]
C0427460
%
Platelets
Description

Platelets

Data type

float

Measurement units
  • 10^9/L
Alias
UMLS CUI [1]
C0005821
10^9/L
Mean platelet volume
Description

Mean platelet volume

Data type

integer

Measurement units
  • FL
Alias
UMLS CUI [1]
C0200665
FL
Neutrophils
Description

Neutrophils

Data type

float

Measurement units
  • 10^9/L
Alias
UMLS CUI [1]
C0948762
10^9/L
Lymphocytes
Description

Lymphocytes

Data type

float

Measurement units
  • 10^9/L
Alias
UMLS CUI [1]
C0024264
10^9/L
Monocytes
Description

Monocytes

Data type

float

Measurement units
  • 10^9/L
Alias
UMLS CUI [1]
C0026473
10^9/L
Eosinophils
Description

Eosinophils

Data type

float

Measurement units
  • 10^9/L
Alias
UMLS CUI [1]
C0200638
10^9/L
Basophils
Description

Basophils

Data type

float

Measurement units
  • 10^9/L
Alias
UMLS CUI [1]
C0200641
10^9/L
Reticulocytes
Description

Reticulocytes

Data type

float

Measurement units
  • 10^9/L
Alias
UMLS CUI [1]
C0035286
10^9/L
Blood Chemistry
Description

Blood Chemistry

Alias
UMLS CUI-1
C0005774
Total Protein
Description

Total Protein

Data type

float

Measurement units
  • g/dL
Alias
UMLS CUI [1]
C0036836
g/dL
Albumin
Description

Albumin

Data type

float

Measurement units
  • g/dL
Alias
UMLS CUI [1]
C0201838
g/dL
Calcium total
Description

Calcium total

Data type

float

Measurement units
  • mg/dL
Alias
UMLS CUI [1]
C0600069
mg/dL
Glucose
Description

Glucose

Data type

float

Measurement units
  • mg/dl
Alias
UMLS CUI [1]
C0202042
mg/dl
Total Bilirubin
Description

Bilirubin, total

Data type

float

Measurement units
  • mg/dL
Alias
UMLS CUI [1]
C0201913
mg/dL
Direct Bilirubin
Description

Direct Bilirubin

Data type

float

Measurement units
  • mg/dL
Alias
UMLS CUI [1]
C0201916
mg/dL
Indirect Bilirubin
Description

Indirect Bilirubin

Data type

float

Measurement units
  • mg/dl
Alias
UMLS CUI [1]
C1881193
mg/dl
AST (SGOT)
Description

AST

Data type

float

Measurement units
  • IU/L
Alias
UMLS CUI [1]
C0201899
IU/L
ALT (SGPT)
Description

ALT

Data type

float

Measurement units
  • IU/L
Alias
UMLS CUI [1]
C0201836
IU/L
Sodium
Description

Sodium

Data type

float

Measurement units
  • mmol/L
Alias
UMLS CUI [1]
C0337443
mmol/L
Potassium
Description

Potassium

Data type

float

Measurement units
  • mmol/l
Alias
UMLS CUI [1]
C0202194
mmol/l
Chloride
Description

Chloride

Data type

float

Measurement units
  • mmol/L
Alias
UMLS CUI [1]
C0201952
mmol/L
Uric acid
Description

Uric acid

Data type

float

Measurement units
  • mg/dL
Alias
UMLS CUI [1]
C0041980
mg/dL
GGT
Description

GGT

Data type

float

Measurement units
  • IU/L
Alias
UMLS CUI [1]
C0202035
IU/L
Hep B surface antigen
Description

Hep B surface antigen

Data type

integer

Alias
UMLS CUI [1]
C0201477
Hepatitis C antibody
Description

Hepatitis C antibody

Data type

integer

Alias
UMLS CUI [1]
C0281863
HIV antibody
Description

HIV antibody

Data type

integer

Alias
UMLS CUI [1]
C0019683
Total carbon dioxide
Description

carbon dioxide

Data type

float

Measurement units
  • mmol/L
Alias
UMLS CUI [1]
C0201930
mmol/L
Phosphate
Description

Phosphate

Data type

float

Measurement units
  • mg/dL
Alias
UMLS CUI [1]
C0523826
mg/dL
Haptoglobin
Description

Haptoglobin

Data type

float

Measurement units
  • mg/dL
Alias
UMLS CUI [1]
C0919773
mg/dL
Lactate Dehydrogenase
Description

Lactate Dehydrogenase

Data type

float

Measurement units
  • IU/L
Alias
UMLS CUI [1]
C0202113
IU/L
Urinalysis
Description

Urinalysis

Alias
UMLS CUI-1
C0042014
Specific gravity
Description

Urine Specific Gravity

Data type

float

Alias
UMLS CUI [1]
C0202517
PH
Description

PH urine

Data type

integer

Alias
UMLS CUI [1]
C0042044
Protein
Description

Urine Protein

Data type

integer

Alias
UMLS CUI [1]
C0262923
Urine glucose
Description

Urine glucose

Data type

integer

Alias
UMLS CUI [1]
C0004076
Ketones
Description

Urine Ketones

Data type

float

Alias
UMLS CUI [1,1]
C1991100
UMLS CUI [1,2]
C0042014
Occult blood
Description

occult blood dipstick

Data type

integer

Alias
UMLS CUI [1]
C2188744
Urine RBC
Description

urine RBC

Data type

integer

Measurement units
  • /HPF
Alias
UMLS CUI [1]
C1972472
/HPF
urine WBC
Description

urine WBC

Data type

integer

Measurement units
  • /HPF
Alias
UMLS CUI [1]
C1975554
/HPF
Squamous epithelial cells
Description

Squamous epithelial cells

Data type

integer

Measurement units
  • /HPF
Alias
UMLS CUI [1]
C2699511
/HPF
Transitional epithelial cells
Description

Transitional epithelial cells

Data type

integer

Measurement units
  • /HPF
Alias
UMLS CUI [1]
C2984936
/HPF
Hyaline casts
Description

Hyaline casts

Data type

float

Measurement units
  • /LPF
Alias
UMLS CUI [1]
C0427894
/LPF
unknown cells
Description

unknown cells urine

Data type

integer

Measurement units
  • /HPF
Alias
UMLS CUI [1]
C0854148
/HPF
Coarse gran casts
Description

Coarse granulocytes

Data type

integer

Measurement units
  • /LPF
Alias
UMLS CUI [1]
C1868540
/LPF
Uric acid crystals
Description

Uric acid crystals

Data type

integer

Measurement units
  • /HPF
Alias
UMLS CUI [1]
C2700121
/HPF
Tri phosphate crystals
Description

Tri phosphate crystals

Data type

integer

Measurement units
  • /HPF
Alias
UMLS CUI [1]
C0370102
/HPF
Unknown crystals
Description

urine crystals

Data type

integer

Measurement units
  • /HPF
Alias
UMLS CUI [1]
C0427897
/HPF
WBC casts
Description

WBC casts

Data type

integer

Measurement units
  • /LPF
Alias
UMLS CUI [1]
C2700271
/LPF
Epithelial cell casts
Description

Epithelial cells urine

Data type

integer

Measurement units
  • /LPF
Alias
UMLS CUI [1]
C1318314
/LPF
fine granular casts
Description

fine granular casts

Data type

integer

Measurement units
  • /LPF
Alias
UMLS CUI [1]
C2697522
/LPF
mixed cellular casts
Description

mixed cellular casts

Data type

integer

Measurement units
  • /LPF
Alias
UMLS CUI [1]
C1317541
/LPF
Renal tubular epithelial
Description

Renal tubular epithelial

Data type

integer

Measurement units
  • /HPF
Alias
UMLS CUI [1]
C2700087
/HPF
RBC casts
Description

RBC casts

Data type

integer

Measurement units
  • /LPF
Alias
UMLS CUI [1]
C2699019
/LPF
Waxy casts
Description

Waxy casts

Data type

integer

Measurement units
  • /LPF
Alias
UMLS CUI [1]
C2700267
/LPF
unknown casts
Description

unknown casts

Data type

integer

Measurement units
  • /LPF
Alias
UMLS CUI [1,1]
C4048266
UMLS CUI [1,2]
C0439673
/LPF
Amorphous phosphate crystals
Description

Amorphous phosphate crystals

Data type

integer

Measurement units
  • /HPF
Alias
UMLS CUI [1]
C2984932
/HPF
Amorphous urate crystals
Description

Amorphous urate crystals

Data type

integer

Measurement units
  • /HPF
Alias
UMLS CUI [1]
C2984933
/HPF
Bacteria
Description

bacteriuria

Data type

integer

Alias
UMLS CUI [1]
C0004659
Oval fat body
Description

Oval fat body

Data type

integer

Alias
UMLS CUI [1]
C1699553
Urine yeast
Description

Urine yeast

Data type

integer

Alias
UMLS CUI [1]
C2188427
Trichomonas
Description

Trichomonas

Data type

boolean

Alias
UMLS CUI [1]
C2984927
Hemosiderin
Description

Hemosiderin

Data type

boolean

Alias
UMLS CUI [1]
C0019113
Urine Chemistry
Description

Urine Chemistry

Alias
UMLS CUI-1
C0864414
Alk Phos total
Description

Alk Phos Value

Data type

float

Measurement units
  • IU/L
IU/L
Pregnancy test
Description

Pregnancy dipstick

Data type

integer

Alias
UMLS CUI [1]
C0032976
Blood Urea Nitrogen
Description

Blood Urea Nitrogen

Data type

float

Measurement units
  • mg/dl
Alias
UMLS CUI [1]
C0005845
mg/dl
Creatinine
Description

Creatinine

Data type

float

Measurement units
  • mg/dL
Alias
UMLS CUI [1]
C0201975
mg/dL
FSH
Description

FSH

Data type

float

Measurement units
  • MIU/ML
Alias
UMLS CUI [1]
C0202022
MIU/ML
Triglycerides
Description

Triglycerides

Data type

float

Measurement units
  • mg/dL
Alias
UMLS CUI [1]
C0202236
mg/dL
Ethanol
Description

Ethanol

Data type

float

Measurement units
  • mg/dL
Alias
UMLS CUI [1]
C0202304
mg/dL
Creatinine kinase
Description

Creatinine kinase

Data type

float

Measurement units
  • mg/dl
Alias
UMLS CUI [1]
C0201973
mg/dl
Cholesterol
Description

Cholesterol

Data type

float

Measurement units
  • mg/dL
Alias
UMLS CUI [1]
C1445957
mg/dL
Estradiol
Description

Estradiol

Data type

float

Measurement units
  • pg/mL
Alias
UMLS CUI [1,1]
C0014912
UMLS CUI [1,2]
C0008000
pg/mL
Calcium oxalate crystals
Description

Calcium oxalate crystals

Data type

integer

Measurement units
  • /LPF
Alias
UMLS CUI [1]
C0368818
/LPF
Urine drug screening
Description

Urine drug screening

Alias
UMLS CUI-1
C0202274
Amphetamine
Description

Amphetamine

Data type

boolean

Alias
UMLS CUI [1]
C0002667
Barbiturates
Description

Barbiturates

Data type

integer

Alias
UMLS CUI [1]
C0004745
Benzodiazepines
Description

Benzodiazepines

Data type

integer

Alias
UMLS CUI [1]
C0005064
Cannabinoids
Description

Cannabinoids

Data type

integer

Alias
UMLS CUI [1]
C0006864
Cocaine/Metabs
Description

Cocaine

Data type

integer

Alias
UMLS CUI [1]
C0009170
Opiates
Description

Opiates

Data type

integer

Alias
UMLS CUI [1]
C0376196
PCP
Description

PCP

Data type

integer

Alias
UMLS CUI [1]
C1744653
Cotinine
Description

Cotinine

Data type

integer

Alias
UMLS CUI [1]
C0202363
Blood smear
Description

Blood smear

Alias
UMLS CUI-1
C2238079
Blood smear normal or abnormal?
Description

Blood smear

Data type

text

Alias
UMLS CUI [1]
C1167864
UMLS CUI [2]
C1167865

Similar models

Safety Lab - GSK Study: GW679769 administered alone vs. with dexamethasone - Evaluation of safety, tolerability and pharmacokinetics NCT00291876

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Hematology
C0018941 (UMLS CUI-1)
Leukocytes (WBC)
Item
WBC
float
C0023508 (UMLS CUI [1])
Red Blood Count
Item
Red cells
float
C1287262 (UMLS CUI [1])
Hematocrit
Item
Hematocrit (PCV)
float
C0518014 (UMLS CUI [1])
Mean cell volume
Item
Mean cell volume
integer
C0524587 (UMLS CUI [1])
Mean cell hemoglobin (MCH)
Item
Mean cell hemoglobin (MCH)
float
C0369183 (UMLS CUI [1])
MCHC
Item
MCHC
float
C0474535 (UMLS CUI [1])
rdw
Item
RBC distribution width
float
C0427460 (UMLS CUI [1])
Platelets
Item
Platelets
float
C0005821 (UMLS CUI [1])
Mean platelet volume
Item
Mean platelet volume
integer
C0200665 (UMLS CUI [1])
Neutrophils
Item
Neutrophils
float
C0948762 (UMLS CUI [1])
Lymphocytes
Item
Lymphocytes
float
C0024264 (UMLS CUI [1])
Monocytes
Item
Monocytes
float
C0026473 (UMLS CUI [1])
Eosinophils
Item
Eosinophils
float
C0200638 (UMLS CUI [1])
Basophils
Item
Basophils
float
C0200641 (UMLS CUI [1])
Reticulocytes
Item
Reticulocytes
float
C0035286 (UMLS CUI [1])
Item Group
Blood Chemistry
C0005774 (UMLS CUI-1)
Total Protein
Item
Total Protein
float
C0036836 (UMLS CUI [1])
Albumin
Item
Albumin
float
C0201838 (UMLS CUI [1])
Calcium total
Item
Calcium total
float
C0600069 (UMLS CUI [1])
Glucose
Item
Glucose
float
C0202042 (UMLS CUI [1])
Bilirubin, total
Item
Total Bilirubin
float
C0201913 (UMLS CUI [1])
Direct Bilirubin
Item
Direct Bilirubin
float
C0201916 (UMLS CUI [1])
Indirect Bilirubin
Item
Indirect Bilirubin
float
C1881193 (UMLS CUI [1])
AST
Item
AST (SGOT)
float
C0201899 (UMLS CUI [1])
ALT
Item
ALT (SGPT)
float
C0201836 (UMLS CUI [1])
Sodium
Item
Sodium
float
C0337443 (UMLS CUI [1])
Potassium
Item
Potassium
float
C0202194 (UMLS CUI [1])
Chloride
Item
Chloride
float
C0201952 (UMLS CUI [1])
Uric acid
Item
Uric acid
float
C0041980 (UMLS CUI [1])
GGT
Item
GGT
float
C0202035 (UMLS CUI [1])
Item
Hep B surface antigen
integer
C0201477 (UMLS CUI [1])
Code List
Hep B surface antigen
CL Item
positive (1)
CL Item
negative (2)
Item
Hepatitis C antibody
integer
C0281863 (UMLS CUI [1])
Code List
Hepatitis C antibody
CL Item
Positive (1)
CL Item
Negative (2)
Item
HIV antibody
integer
C0019683 (UMLS CUI [1])
Code List
HIV antibody
CL Item
Positive (1)
CL Item
Negative (2)
carbon dioxide
Item
Total carbon dioxide
float
C0201930 (UMLS CUI [1])
Phosphate
Item
Phosphate
float
C0523826 (UMLS CUI [1])
Haptoglobin
Item
Haptoglobin
float
C0919773 (UMLS CUI [1])
Lactate Dehydrogenase
Item
Lactate Dehydrogenase
float
C0202113 (UMLS CUI [1])
Item Group
Urinalysis
C0042014 (UMLS CUI-1)
Urine Specific Gravity
Item
Specific gravity
float
C0202517 (UMLS CUI [1])
PH urine
Item
PH
integer
C0042044 (UMLS CUI [1])
Item
Protein
integer
C0262923 (UMLS CUI [1])
Code List
Protein
CL Item
negative (1)
CL Item
positive (2)
Item
Urine glucose
integer
C0004076 (UMLS CUI [1])
Code List
Urine glucose
CL Item
negative (1)
CL Item
positive (2)
Urine Ketones
Item
Ketones
float
C1991100 (UMLS CUI [1,1])
C0042014 (UMLS CUI [1,2])
Item
Occult blood
integer
C2188744 (UMLS CUI [1])
Code List
Occult blood
CL Item
positive (1)
CL Item
negative (2)
urine RBC
Item
Urine RBC
integer
C1972472 (UMLS CUI [1])
urine WBC
Item
urine WBC
integer
C1975554 (UMLS CUI [1])
Squamous epithelial cells
Item
Squamous epithelial cells
integer
C2699511 (UMLS CUI [1])
Transitional epithelial cells
Item
Transitional epithelial cells
integer
C2984936 (UMLS CUI [1])
Hyaline casts
Item
Hyaline casts
float
C0427894 (UMLS CUI [1])
unknown cells urine
Item
unknown cells
integer
C0854148 (UMLS CUI [1])
Coarse granulocytes
Item
Coarse gran casts
integer
C1868540 (UMLS CUI [1])
Uric acid crystals
Item
Uric acid crystals
integer
C2700121 (UMLS CUI [1])
Tri phosphate crystals
Item
Tri phosphate crystals
integer
C0370102 (UMLS CUI [1])
urine crystals
Item
Unknown crystals
integer
C0427897 (UMLS CUI [1])
WBC casts
Item
WBC casts
integer
C2700271 (UMLS CUI [1])
Epithelial cells urine
Item
Epithelial cell casts
integer
C1318314 (UMLS CUI [1])
fine granular casts
Item
fine granular casts
integer
C2697522 (UMLS CUI [1])
mixed cellular casts
Item
mixed cellular casts
integer
C1317541 (UMLS CUI [1])
Renal tubular epithelial
Item
Renal tubular epithelial
integer
C2700087 (UMLS CUI [1])
RBC casts
Item
RBC casts
integer
C2699019 (UMLS CUI [1])
Waxy casts
Item
Waxy casts
integer
C2700267 (UMLS CUI [1])
unknown casts
Item
unknown casts
integer
C4048266 (UMLS CUI [1,1])
C0439673 (UMLS CUI [1,2])
Amorphous phosphate crystals
Item
Amorphous phosphate crystals
integer
C2984932 (UMLS CUI [1])
Amorphous urate crystals
Item
Amorphous urate crystals
integer
C2984933 (UMLS CUI [1])
Item
Bacteria
integer
C0004659 (UMLS CUI [1])
Code List
Bacteria
CL Item
negative (1)
CL Item
positive (2)
Item
Oval fat body
integer
C1699553 (UMLS CUI [1])
Code List
Oval fat body
CL Item
negative (1)
CL Item
positive (2)
Item
Urine yeast
integer
C2188427 (UMLS CUI [1])
Code List
Urine yeast
CL Item
negative (1)
CL Item
positive (2)
Trichomonas
Item
Trichomonas
boolean
C2984927 (UMLS CUI [1])
Hemosiderin
Item
Hemosiderin
boolean
C0019113 (UMLS CUI [1])
Item Group
Urine Chemistry
C0864414 (UMLS CUI-1)
Alk Phos Value
Item
Alk Phos total
float
Item
Pregnancy test
integer
C0032976 (UMLS CUI [1])
Code List
Pregnancy test
CL Item
negative (1)
CL Item
positive (2)
Blood Urea Nitrogen
Item
Blood Urea Nitrogen
float
C0005845 (UMLS CUI [1])
Creatinine
Item
Creatinine
float
C0201975 (UMLS CUI [1])
FSH
Item
FSH
float
C0202022 (UMLS CUI [1])
Triglycerides
Item
Triglycerides
float
C0202236 (UMLS CUI [1])
Ethanol
Item
Ethanol
float
C0202304 (UMLS CUI [1])
Creatinine kinase
Item
Creatinine kinase
float
C0201973 (UMLS CUI [1])
Cholesterol
Item
Cholesterol
float
C1445957 (UMLS CUI [1])
Estradiol
Item
Estradiol
float
C0014912 (UMLS CUI [1,1])
C0008000 (UMLS CUI [1,2])
Calcium oxalate crystals
Item
Calcium oxalate crystals
integer
C0368818 (UMLS CUI [1])
Item Group
Urine drug screening
C0202274 (UMLS CUI-1)
Amphetamine
Item
Amphetamine
boolean
C0002667 (UMLS CUI [1])
Item
Barbiturates
integer
C0004745 (UMLS CUI [1])
Code List
Barbiturates
CL Item
positive (1)
CL Item
negative (2)
Item
Benzodiazepines
integer
C0005064 (UMLS CUI [1])
Code List
Benzodiazepines
CL Item
negative (1)
CL Item
positive (2)
Item
Cannabinoids
integer
C0006864 (UMLS CUI [1])
Code List
Cannabinoids
CL Item
negative (1)
CL Item
positive (2)
Item
Cocaine/Metabs
integer
C0009170 (UMLS CUI [1])
Code List
Cocaine/Metabs
CL Item
positive (1)
CL Item
negative (2)
Item
Opiates
integer
C0376196 (UMLS CUI [1])
Code List
Opiates
CL Item
positive (1)
CL Item
negative (2)
Item
PCP
integer
C1744653 (UMLS CUI [1])
Code List
PCP
CL Item
negative (1)
CL Item
positive (2)
Item
Cotinine
integer
C0202363 (UMLS CUI [1])
Code List
Cotinine
CL Item
negative (1)
CL Item
positive (2)
Item Group
Blood smear
C2238079 (UMLS CUI-1)
Item
Blood smear normal or abnormal?
text
C1167864 (UMLS CUI [1])
C1167865 (UMLS CUI [2])
Code List
Blood smear normal or abnormal?
CL Item
normal (1)
CL Item
abnormal (2)