Schizophrenia disease length
Item
diagnosed with schizophrenia according to the diagnostic and statistical manual of mental disorders, fourth edition (dsm-iv) (295.10, 295.20, 295.30, 295.60, 295.90) at least 1 year before screening
boolean
C0036341 (UMLS CUI [1,1])
C0872146 (UMLS CUI [1,2])
Acute schizophrenic episode Positive and negative syndrome scale
Item
experiencing an acute episode with a total panss score at screening of between 70 and 120
boolean
C0813173 (UMLS CUI [1,1])
C0451383 (UMLS CUI [1,2])
Healthy | Exception Schizophrenia
Item
are otherwise physically healthy
boolean
C3898900 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0036341 (UMLS CUI [2,2])
Hospital stay duration Voluntary Agree
Item
agree to at least 8 days of voluntary hospitalization.
boolean
C4019086 (UMLS CUI [1,1])
C0439656 (UMLS CUI [1,2])
C3641827 (UMLS CUI [1,3])
Axis I diagnosis | Exception Schizophrenia | Exception Nicotine Dependence | Exception Caffeine dependence
Item
active comorbid dsm-iv axis i diagnosis other than schizophrenia (nicotine and caffeine dependence are not exclusionary)
boolean
C0270287 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0036341 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0028043 (UMLS CUI [3,2])
C1705847 (UMLS CUI [4,1])
C1386553 (UMLS CUI [4,2])
Antidepressive Agents | Exception Antidepressive Agents Dose Stable | Exception Monoamine Oxidase Inhibitors
Item
treatment with antidepressants (unless a subject has been on a stable dosage for at least 3 months before baseline) other than monoamine oxidase inhibitors
boolean
C0003289 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0003289 (UMLS CUI [2,2])
C0178602 (UMLS CUI [2,3])
C0205360 (UMLS CUI [2,4])
C1705847 (UMLS CUI [3,1])
C0026457 (UMLS CUI [3,2])
Substance Dependence | Exception Nicotine Dependence | Exception Caffeine dependence
Item
dsm-iv diagnosis of substance dependence within 6 months before screening evaluation (nicotine and caffeine dependence are not exclusionary)
boolean
C0038580 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0028043 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C1386553 (UMLS CUI [3,2])
Medical condition Affecting Absorption Investigational New Drugs | Medical condition Affecting Metabolism Investigational New Drugs | Medical condition Affecting Excretion Investigational New Drugs | Crohn Disease | Liver diseases | Kidney Diseases
Item
any medical condition that could potentially alter the absorption, metabolism, or excretion of the study medication, such as crohn's disease, liver disease, or renal disease
boolean
C3843040 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0237442 (UMLS CUI [1,3])
C0013230 (UMLS CUI [1,4])
C3843040 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C2698779 (UMLS CUI [2,3])
C0013230 (UMLS CUI [2,4])
C3843040 (UMLS CUI [3,1])
C0392760 (UMLS CUI [3,2])
C2699704 (UMLS CUI [3,3])
C0013230 (UMLS CUI [3,4])
C0010346 (UMLS CUI [4])
C0023895 (UMLS CUI [5])
C0022658 (UMLS CUI [6])
Cardiovascular Diseases | Respiration Disorders | Nervous system disorder | Seizures | Cerebrovascular Disorders | Kidney Diseases | Liver diseases | Endocrine System Diseases | Immune System Diseases | Cardiovascular Diseases Unstable | Respiration Disorders Unstable | Nervous system disorder Unstable | Seizures Unstable | Cerebrovascular Disorders Unstable | Kidney Diseases Unstable | Liver diseases Unstable | Endocrine System Diseases Unstable | Immune System Diseases Unstable
Item
relevant history of any significant or unstable cardiovascular, respiratory, neurologic (including seizures or significant cerebrovascular), renal, hepatic, endocrine, or immunologic disease.
boolean
C0007222 (UMLS CUI [1])
C0035204 (UMLS CUI [2])
C0027765 (UMLS CUI [3])
C0036572 (UMLS CUI [4])
C0007820 (UMLS CUI [5])
C0022658 (UMLS CUI [6])
C0023895 (UMLS CUI [7])
C0014130 (UMLS CUI [8])
C0021053 (UMLS CUI [9])
C0007222 (UMLS CUI [10,1])
C0443343 (UMLS CUI [10,2])
C0035204 (UMLS CUI [11,1])
C0443343 (UMLS CUI [11,2])
C0027765 (UMLS CUI [12,1])
C0443343 (UMLS CUI [12,2])
C0036572 (UMLS CUI [13,1])
C0443343 (UMLS CUI [13,2])
C0007820 (UMLS CUI [14,1])
C0443343 (UMLS CUI [14,2])
C0022658 (UMLS CUI [15,1])
C0443343 (UMLS CUI [15,2])
C0023895 (UMLS CUI [16,1])
C0443343 (UMLS CUI [16,2])
C0014130 (UMLS CUI [17,1])
C0443343 (UMLS CUI [17,2])
C0021053 (UMLS CUI [18,1])
C0443343 (UMLS CUI [18,2])