Parkinson Disease Probable | Motor function Main Quantity Parkinson Disease | Resting Tremor | Rigidity | Bradykinesia | Dopamine Agonists Good therapeutic response
Item
1. diagnosis of "probable" pd, defined by the presence of at least 2 out of 3 cardinal motor features of pd (resting tremor, rigidity, and bradykinesia, plus a sustained and significant response to dopaminergic treatment);
boolean
C0030567 (UMLS CUI [1,1])
C0332148 (UMLS CUI [1,2])
C0234130 (UMLS CUI [2,1])
C1542147 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0030567 (UMLS CUI [2,4])
C0234379 (UMLS CUI [3])
C0026837 (UMLS CUI [4])
C0233565 (UMLS CUI [5])
C0178601 (UMLS CUI [6,1])
C0184785 (UMLS CUI [6,2])
Age
Item
2. age 30 or over; and
boolean
C0001779 (UMLS CUI [1])
Pharmaceutical Preparations Stable
Item
3. on stable medications for at least 30 days.
boolean
C0013227 (UMLS CUI [1,1])
C0205360 (UMLS CUI [1,2])
Feature Suggestive of Causes Parkinsonian Disorders
Item
1. features suggestive of other causes of parkinsonism/ parkinson-plus syndromes;
boolean
C2348519 (UMLS CUI [1,1])
C0332299 (UMLS CUI [1,2])
C0015127 (UMLS CUI [1,3])
C0242422 (UMLS CUI [1,4])
Deep Brain Stimulation | Ablation | Headache Significant | Epilepsy | Mass lesion of brain | Craniocerebral Trauma Major | Unconscious State Duration
Item
2. history of deep brain stimulation or ablation surgery, significant headaches, epilepsy or seizure disorder, mass brain lesions, or major head trauma leading to loss of consciousness of any length;
boolean
C0394162 (UMLS CUI [1])
C0547070 (UMLS CUI [2])
C0018681 (UMLS CUI [3,1])
C0750502 (UMLS CUI [3,2])
C0014544 (UMLS CUI [4])
C0742078 (UMLS CUI [5])
C0018674 (UMLS CUI [6,1])
C0205164 (UMLS CUI [6,2])
C0041657 (UMLS CUI [7,1])
C0449238 (UMLS CUI [7,2])
Epilepsy First Degree Relative
Item
3. family (1st degree relatives) history of epilepsy;
boolean
C0014544 (UMLS CUI [1,1])
C1517194 (UMLS CUI [1,2])
Dementia
Item
4. evidence for dementia;
boolean
C0497327 (UMLS CUI [1])
Medical contraindication fMRI
Item
5. presence of contraindications for functional magnetic resonance imaging (fmri);
boolean
C1301624 (UMLS CUI [1,1])
C0376335 (UMLS CUI [1,2])
Schizophrenia | Schizoaffective Disorder | Psychotic Disorders | Bipolar Disorder cycling rapid | Substance Use Disorders
Item
6. history of schizophrenia, schizoaffective disorder, other psychosis, rapid-cycling bipolar illness, alcohol/drug abuse within the past year;
boolean
C0036341 (UMLS CUI [1])
C0036337 (UMLS CUI [2])
C0033975 (UMLS CUI [3])
C0005586 (UMLS CUI [4,1])
C1511572 (UMLS CUI [4,2])
C0456962 (UMLS CUI [4,3])
C0038586 (UMLS CUI [5])
Clinical Response Rapid Needed | Initiation | Psychotic Disorders | Suicidality
Item
7. need for rapid clinical response due to conditions such as initiation, psychosis, or suicidality;
boolean
C4055223 (UMLS CUI [1,1])
C0456962 (UMLS CUI [1,2])
C0027552 (UMLS CUI [1,3])
C1704686 (UMLS CUI [2])
C0033975 (UMLS CUI [3])
C3166387 (UMLS CUI [4])
Medical condition Unstable | Diabetes Mellitus | Heart Diseases | Hypertensive disease
Item
8. unstable medical condition such as diabetes, cardiac disease, hypertension;
boolean
C3843040 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C0011849 (UMLS CUI [2])
C0018799 (UMLS CUI [3])
C0020538 (UMLS CUI [4])
Pregnancy
Item
9. pregnancy; and
boolean
C0032961 (UMLS CUI [1])
Dyschromatopsia
Item
10. colorblindness.
boolean
C0858618 (UMLS CUI [1])