Non-Small Cell Lung Carcinoma | Squamous cell carcinoma of lung | Adenocarcinoma of lung | Large cell carcinoma of lung
Item
histologically confirmed non-small cell lung cancer, the pathology type includes squamous cell carcinoma, adenocarcinoma, large-cell carcinoma, and any mixed type of the 3 types mentioned above.
boolean
C0007131 (UMLS CUI [1])
C0149782 (UMLS CUI [2])
C0152013 (UMLS CUI [3])
C0345958 (UMLS CUI [4])
TNM clinical staging Non-Small Cell Lung Carcinoma Complete excision | Lobectomy | LUNG LEFT PNEUMONECTOMY | Bilobectomy of lung
Item
stage ib-iiia non-small cell lung cancer, tumor was completely resected (the type of surgery including lobectomy, left side pneumonectomy,bi-lobectomy).
boolean
C3258246 (UMLS CUI [1,1])
C0007131 (UMLS CUI [1,2])
C0015250 (UMLS CUI [1,3])
C0023928 (UMLS CUI [2])
C0746125 (UMLS CUI [3])
C0396580 (UMLS CUI [4])
Operative Surgical Procedures | Chemotherapy, Adjuvant
Item
the time from surgery to first dose of adjuvant chemotherapy are mandatory between 4-8 weeks.
boolean
C0543467 (UMLS CUI [1])
C0085533 (UMLS CUI [2])
Recurrent tumor Absent | Adjuvant therapy
Item
no evidence of tumor relapse prior to adjuvant therapy.
boolean
C0521158 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0677850 (UMLS CUI [2])
Age | ECOG performance status
Item
age 18-70, ecog performance status 0-1.
boolean
C0001779 (UMLS CUI [1])
C1520224 (UMLS CUI [2])
Hematologic function | Renal function | Liver function | Cardiac function | Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement
Item
normal hematologic function.renal function , hepatic and cardiac function will be within the acceptable ranges as following:serum bilirubin, ast and alt levels below 1.5 times of normal value.
boolean
C0221130 (UMLS CUI [1])
C0232804 (UMLS CUI [2])
C0232741 (UMLS CUI [3])
C0232164 (UMLS CUI [4])
C1278039 (UMLS CUI [5])
C0201899 (UMLS CUI [6])
C0201836 (UMLS CUI [7])
Chemotherapy Absent | Therapeutic radiology procedure Absent
Item
no history of chemotherapy or radiotherapy;
boolean
C0392920 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1522449 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Compliance behavior Chemotherapy | Compliance behavior Follow-up | Informed Consent
Item
the patient should have well compliance for chemotherapy and follow up.informed consent should be obtained before treatment.
boolean
C1321605 (UMLS CUI [1,1])
C0392920 (UMLS CUI [1,2])
C1321605 (UMLS CUI [2,1])
C3274571 (UMLS CUI [2,2])
C0021430 (UMLS CUI [3])
Documents Histologic Mismatch Inclusion criteria | Documents Cytologic Mismatch Inclusion criteria
Item
the histological or cytological documents do not match the inclusion criteria.
boolean
C1301746 (UMLS CUI [1,1])
C0205462 (UMLS CUI [1,2])
C1881865 (UMLS CUI [1,3])
C1512693 (UMLS CUI [1,4])
C1301746 (UMLS CUI [2,1])
C0205471 (UMLS CUI [2,2])
C1881865 (UMLS CUI [2,3])
C1512693 (UMLS CUI [2,4])
LUNG RIGHT PNEUMONECTOMY | Excision Incomplete
Item
right side pneumonectomy or any kind of incompletely resected surgery.
boolean
C0746225 (UMLS CUI [1])
C0728940 (UMLS CUI [2,1])
C0205257 (UMLS CUI [2,2])
Recruitment Time period Relationship Operative Surgical Procedures
Item
the recruitment time are beyond 8 weeks from surgery.
boolean
C0242800 (UMLS CUI [1,1])
C1948053 (UMLS CUI [1,2])
C0439849 (UMLS CUI [1,3])
C0543467 (UMLS CUI [1,4])
Systemic disease Risk Increase Research | Mental disorders Risk Increase Research | Systemic disease Risk Increase Therapeutic procedure | Mental disorders Risk Increase Therapeutic procedure | Systemic disease Affecting Analysis Research results | Mental disorders Affecting Analysis Research results | Uncontrolled hypertension | Angina, Unstable | Myocardial Infarction | Cardiac Arrhythmia Uncontrolled | Congestive heart failure Symptoms | Anemia Electrocardiography | Heart valve disease | Bacterial Infections | Virus Diseases | Mycoses | Cardiac Arrhythmia Grade | Myocardial Anemia Grade | Cardiac Troponin T Abnormal Grade | Hypertensive disease Grade | Left ventricular ejection fraction
Item
any concurrent acute or chronic systemic diseases or psychiatric diseases, which might both increase the risks of the research itself or the medical therapy and influence the research results analysis. the researchers can make a judge for the following conditions to tell whether they are fit for this research:uncontrolled high blood pressure, unstable angina , myocardial infarction , uncontrolled arrhythmia,or congestive heart failure with clinical symptoms within 12 weeks before randomization.evidence of anemia from electrocardiographic manifestation or heart valve disease with confirmed clinical diagnosis.clinically significant active infection state due to bacteria, virus and fungi invasion. patients with grade ii arrhythmia, grade ii myocardial anemia, grade ii abnormal cardiac troponin t, grade ii high blood pressure or left ventricle ejection fraction (lvef) less than 50 percent according to ctc 3.0 are not permitted to enrol the study.
boolean
C0442893 (UMLS CUI [1,1])
C0035647 (UMLS CUI [1,2])
C0442805 (UMLS CUI [1,3])
C0035168 (UMLS CUI [1,4])
C0004936 (UMLS CUI [2,1])
C0035647 (UMLS CUI [2,2])
C0442805 (UMLS CUI [2,3])
C0035168 (UMLS CUI [2,4])
C0442893 (UMLS CUI [3,1])
C0035647 (UMLS CUI [3,2])
C0442805 (UMLS CUI [3,3])
C0087111 (UMLS CUI [3,4])
C0004936 (UMLS CUI [4,1])
C0035647 (UMLS CUI [4,2])
C0442805 (UMLS CUI [4,3])
C0087111 (UMLS CUI [4,4])
C0442893 (UMLS CUI [5,1])
C0392760 (UMLS CUI [5,2])
C0936012 (UMLS CUI [5,3])
C0683954 (UMLS CUI [5,4])
C0004936 (UMLS CUI [6,1])
C0392760 (UMLS CUI [6,2])
C0936012 (UMLS CUI [6,3])
C0683954 (UMLS CUI [6,4])
C1868885 (UMLS CUI [7])
C0002965 (UMLS CUI [8])
C0027051 (UMLS CUI [9])
C0003811 (UMLS CUI [10,1])
C0205318 (UMLS CUI [10,2])
C0018802 (UMLS CUI [11,1])
C1457887 (UMLS CUI [11,2])
C0002871 (UMLS CUI [12,1])
C1623258 (UMLS CUI [12,2])
C0018824 (UMLS CUI [13])
C0004623 (UMLS CUI [14])
C0042769 (UMLS CUI [15])
C0026946 (UMLS CUI [16])
C0003811 (UMLS CUI [17,1])
C0441800 (UMLS CUI [17,2])
C0002871 (UMLS CUI [18,1])
C1522564 (UMLS CUI [18,2])
C0441800 (UMLS CUI [18,3])
C3538889 (UMLS CUI [19,1])
C0205161 (UMLS CUI [19,2])
C0441800 (UMLS CUI [19,3])
C0020538 (UMLS CUI [20,1])
C0441800 (UMLS CUI [20,2])
C0428772 (UMLS CUI [21])
Pregnancy | Breast Feeding
Item
women with pregnant or lactation.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Malignant Neoplasms | Exception Skin carcinoma | Exception Carcinoma in Situ | Exception Prostate carcinoma Early stage Cured
Item
before enter the group,the patients had other malignant tumors except for non-melanoma skin cancer, carcinoma in situ and cured early-stage prostate cancer.
boolean
C0006826 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0699893 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0007099 (UMLS CUI [3,2])
C1705847 (UMLS CUI [4,1])
C0600139 (UMLS CUI [4,2])
C2363430 (UMLS CUI [4,3])
C1880198 (UMLS CUI [4,4])
Hypersensitivity Investigational New Drugs | Allergic Reaction Possible Investigational New Drugs
Item
with allergic constitution or possible allergic reflection to any known research drugs.
boolean
C0020517 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
C1527304 (UMLS CUI [2,1])
C0332149 (UMLS CUI [2,2])
C0013230 (UMLS CUI [2,3])
Poor compliance
Item
poor compliance.
boolean
C0032646 (UMLS CUI [1])
Patient Inappropriate Research
Item
not proper for the research according to the researchers' judgment.
boolean
C0030705 (UMLS CUI [1,1])
C1548788 (UMLS CUI [1,2])
C0035168 (UMLS CUI [1,3])