Non-small cell lung cancer recurrent TNM clinical staging | Pleural effusion
Item
histogically or pathologically determined relapsed/recurrent stage iiib (plueral effusion) or iv nsclc.
boolean
C0278517 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
C0032227 (UMLS CUI [2])
Measurable Disease | Evaluable Disease
Item
measurable or evaluable disease as defined by recist
boolean
C1513041 (UMLS CUI [1])
C1516986 (UMLS CUI [2])
Chemotherapy Regimen Quantity failed | Chemotherapy Refused
Item
must have failed at least one prior chemotherapy regimen or have refused chemotherapy.
boolean
C0392920 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0231175 (UMLS CUI [1,3])
C0392920 (UMLS CUI [2,1])
C1705116 (UMLS CUI [2,2])
ECOG performance status
Item
ecog perfromance status of 0,1, or 2.
boolean
C1520224 (UMLS CUI [1])
Exclusion Criteria
Item
exclusion criteria (include but are not limited to):
boolean
C0680251 (UMLS CUI [1])
Therapeutic radiology procedure | Exception Therapeutic procedure Central Nervous System | Chemotherapy | Investigational New Drugs Non-Cytotoxic | Adrenal Cortex Hormones High dose | Adverse effects of medical drugs Recovery Lacking
Item
radiation therapy (excluding cns therapy) < 2 weeks, chemotherapy, non-cytotoxic investigational agents or high dose corticosteroids within 3 weeks of intitating therpy or patients who have not recovered from adverse effects due to agents administered more than 3 weeks earlier.
boolean
C1522449 (UMLS CUI [1])
C1705847 (UMLS CUI [2,1])
C0087111 (UMLS CUI [2,2])
C3714787 (UMLS CUI [2,3])
C0392920 (UMLS CUI [3])
C0013230 (UMLS CUI [4,1])
C2827065 (UMLS CUI [4,2])
C0001617 (UMLS CUI [5,1])
C0444956 (UMLS CUI [5,2])
C0810090 (UMLS CUI [6,1])
C2004454 (UMLS CUI [6,2])
C0332268 (UMLS CUI [6,3])
Heart Disease New York Heart Association Classification
Item
evidence of new york heart associatation class iii or greater cardiac disease.
boolean
C0018799 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Myocardial Infarction | Cerebrovascular accident | Intervention Cardiovascular
Item
history of myocardial infarction, stroke, or cardiovascular intervention within the last 12 months.
boolean
C0027051 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
C0184661 (UMLS CUI [3,1])
C3887460 (UMLS CUI [3,2])
Antiplatelet Agents | Anticoagulants | Plavix | Coumadin
Item
patients on anti-platlet drugs or anticoagulants such as placix and coumadin.
boolean
C0085826 (UMLS CUI [1])
C0003280 (UMLS CUI [2])
C0633084 (UMLS CUI [3])
C0699129 (UMLS CUI [4])
CNS metastases Systemic | Stable status Post Therapeutic radiology procedure | Adrenal Cortex Hormones Discontinued
Item
systemic central nervous system metastases. the patient must be stable after radiotherapy for >/= to 2 weeks and off corticosteroids for >/= to 1 week.
boolean
C0686377 (UMLS CUI [1,1])
C0205373 (UMLS CUI [1,2])
C0205360 (UMLS CUI [2,1])
C0687676 (UMLS CUI [2,2])
C1522449 (UMLS CUI [2,3])
C0001617 (UMLS CUI [3,1])
C1444662 (UMLS CUI [3,2])
Pregnancy | Breast Feeding
Item
pregnant or nursing women.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Erlotinib Refractory Primary
Item
patients who are primarily refactory to erlotinib.
boolean
C1135135 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
C0205225 (UMLS CUI [1,3])