Age
Item
1. age >=18 to <=70 years
boolean
C0001779 (UMLS CUI [1])
Recurrent Follicular Lymphoma Ann Arbor lymphoma staging system | Refractory Follicular Lymphoma Ann Arbor lymphoma staging system | Follicular Lymphoma transformation | Mantle cell lymphoma | Marginal zone lymphoma | Waldenstrom Macroglobulinemia | Diffuse Large B-Cell Lymphoma
Item
2. relapsed or refractory stage iii or iv, grade 1,2, or 3 follicular lymphoma or transformed follicular lymphoma, mantle cell lymphoma, marginal zone lymphoma, waldenstrom's macroglobulinemia, or diffuse large b-cell lymphoma as defined by the who and:
boolean
C1335701 (UMLS CUI [1,1])
C0432516 (UMLS CUI [1,2])
C1335723 (UMLS CUI [2,1])
C0432516 (UMLS CUI [2,2])
C0024301 (UMLS CUI [3,1])
C1536010 (UMLS CUI [3,2])
C0334634 (UMLS CUI [4])
C0242647 (UMLS CUI [5])
C0024419 (UMLS CUI [6])
C0079744 (UMLS CUI [7])
CD20 Expressing Cell Measurement
Item
expressing the cd 20 antigen
boolean
C3540684 (UMLS CUI [1])
ECOG performance status
Item
ecog performance 0-2
boolean
C1520224 (UMLS CUI [1])
Informed Consent
Item
written informed consent
boolean
C0021430 (UMLS CUI [1])
Collection Peripheral blood stem cells CD34 positive
Item
3. prior collection of at least 2.5x10^6 cd34-positive peripheral blood stem cells/kg.
boolean
C1516698 (UMLS CUI [1,1])
C1518999 (UMLS CUI [1,2])
C0882849 (UMLS CUI [1,3])
Abnormal renal function | Creatinine increased
Item
1. abnormal renal function (creatinine >2.5x upper limit of normal (uln)
boolean
C0151746 (UMLS CUI [1])
C0151578 (UMLS CUI [2])
Liver Dysfunction | Elevated total bilirubin | Alanine aminotransferase increased | Aspartate aminotransferase increased
Item
2. abnormal hepatic function (bilirubin >2xuln, alt/ast >3x uln)
boolean
C0086565 (UMLS CUI [1])
C0741494 (UMLS CUI [2])
C0151905 (UMLS CUI [3])
C0151904 (UMLS CUI [4])
Cardiac ejection fraction
Item
3. cardiac ejection fraction <40%
boolean
C0232174 (UMLS CUI [1])
Pulmonary function tests Defect Severe | Carbon Monoxide Diffusing Capability Test | Pulmonary Function Test/FEV1 | Forced vital capacity | Oxygen Receive
Item
4. severe defects in pulmonary function tests (dlco<70% predicted, fev1, fvc<60% predicted) or receiving continuous oxygen
boolean
C0024119 (UMLS CUI [1,1])
C1457869 (UMLS CUI [1,2])
C0205082 (UMLS CUI [1,3])
C1516251 (UMLS CUI [2])
C0849974 (UMLS CUI [3])
C1287681 (UMLS CUI [4])
C0030054 (UMLS CUI [5,1])
C1514756 (UMLS CUI [5,2])
Human anti-mouse antibody | Hypersensitivity type Zevalin Component | Anaphylaxis Zevalin Component
Item
5. a history of human anti-mouse antibodies (hama) or known type 1 hypersensitivity or anaphylactic proteins to any component of the zevalin therapy.
boolean
C1291910 (UMLS CUI [1])
C0441750 (UMLS CUI [2,1])
C0919274 (UMLS CUI [2,2])
C1705248 (UMLS CUI [2,3])
C0002792 (UMLS CUI [3,1])
C0919274 (UMLS CUI [3,2])
C1705248 (UMLS CUI [3,3])
Pregnancy | Breast Feeding | Reproductive potential Contraceptive methods Lacking
Item
6. female patients who are pregnant or breast feeding, and adults of reproductive potential who are not employing an effective method of birth control during study treatment
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C4034483 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C0332268 (UMLS CUI [3,3])
Therapeutic radiology procedure Bone Marrow Percentage | Therapeutic radiology procedure Gy Lung | Therapeutic radiology procedure Gy Liver | Therapeutic radiology procedure Gy Kidney | Therapeutic radiology procedure Gy Spinal Cord
Item
7. prior radiotherapy to >25% of the bone marrow or >20 gy to critical organ (lung, liver, kidney, spinal cord).
boolean
C1522449 (UMLS CUI [1,1])
C0005953 (UMLS CUI [1,2])
C0439165 (UMLS CUI [1,3])
C1522449 (UMLS CUI [2,1])
C0556636 (UMLS CUI [2,2])
C0024109 (UMLS CUI [2,3])
C1522449 (UMLS CUI [3,1])
C0556636 (UMLS CUI [3,2])
C0023884 (UMLS CUI [3,3])
C1522449 (UMLS CUI [4,1])
C0556636 (UMLS CUI [4,2])
C0022646 (UMLS CUI [4,3])
C1522449 (UMLS CUI [5,1])
C0556636 (UMLS CUI [5,2])
C0037925 (UMLS CUI [5,3])
Central nervous system lymphoma
Item
8. cns lymphoma
boolean
C0742472 (UMLS CUI [1])
Communicable Disease
Item
9. ongoing infection
boolean
C0009450 (UMLS CUI [1])
Radioimmunotherapy
Item
10. prior treatment with radioimmunotherapy
boolean
C0085101 (UMLS CUI [1])