Age
Item
male or female subjects 18 to 65 years inclusive.
boolean
C0001779 (UMLS CUI [1])
Major Depressive Disorder
Item
fulfilled dsm-ⅳ criteria for major depressive disorder.
boolean
C1269683 (UMLS CUI [1])
Disease onset Duration
Item
onset ≧2 weeks.
boolean
C0277793 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
Hamilton Depression Rating Scale 17 Item Questionnaire
Item
baseline score ≧14 on the ham-d17.
boolean
C3639712 (UMLS CUI [1])
Informed Consent
Item
written informed consent prior to entry into the study.
boolean
C0021430 (UMLS CUI [1])
Hamilton Depression Rating Scale 17 Item Questionnaire
Item
ham-d17 item 3 score≧3.
boolean
C3639712 (UMLS CUI [1])
Bipolar Disorder Lifetime | Schizophrenia Lifetime | Schizoaffective Disorder Lifetime
Item
life-time history of bipolar disorders, schizophrenia or schizoaffective disorder.
boolean
C0005586 (UMLS CUI [1,1])
C4071830 (UMLS CUI [1,2])
C0036341 (UMLS CUI [2,1])
C4071830 (UMLS CUI [2,2])
C0036337 (UMLS CUI [3,1])
C4071830 (UMLS CUI [3,2])
Panic Disorder | Obsessive-Compulsive Disorder | Substance Use Disorders
Item
current history of panic disorder, obsessive-compulsive disorder, alcohol or substance abuse.
boolean
C0030319 (UMLS CUI [1])
C0028768 (UMLS CUI [2])
C0038586 (UMLS CUI [3])
Mood disorder due to a general medical condition
Item
mood disorder due to general medical condition.
boolean
C0236747 (UMLS CUI [1])
Antidepressive Agents
Item
treatment with antidepressants at entry into the study before 2 weeks.
boolean
C0003289 (UMLS CUI [1])
Psychotropic Drugs Patient need for | Investigational New Drugs Excluded | Exception Benzodiazepines Quantity Dosage Stable | Exception Hypnotics Quantity Dosage Stable
Item
need for psychoactive medications other than the study drugs, except for one benzodiazepine or hypnotic given at a stable dose.
boolean
C0033978 (UMLS CUI [1,1])
C0686904 (UMLS CUI [1,2])
C0013230 (UMLS CUI [2,1])
C2828389 (UMLS CUI [2,2])
C1705847 (UMLS CUI [3,1])
C0005064 (UMLS CUI [3,2])
C1265611 (UMLS CUI [3,3])
C0178602 (UMLS CUI [3,4])
C0205360 (UMLS CUI [3,5])
C1705847 (UMLS CUI [4,1])
C0020591 (UMLS CUI [4,2])
C1265611 (UMLS CUI [4,3])
C0178602 (UMLS CUI [4,4])
C0205360 (UMLS CUI [4,5])
Intolerance to substance | Drug ineffective
Item
known intolerance or inefficacy to either drug.
boolean
C1744706 (UMLS CUI [1])
C0852908 (UMLS CUI [2])
Antidepressive Agents Quantity Dosage Absent response to treatment
Item
previous lack of response to two or more antidepressants at adequate dosage.
boolean
C0003289 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0178602 (UMLS CUI [1,3])
C0438286 (UMLS CUI [1,4])
Illness | Illness Unstable | Organ failure
Item
subjects who have acute or unstable medical illness or organic failure.
boolean
C0221423 (UMLS CUI [1])
C0221423 (UMLS CUI [2,1])
C0443343 (UMLS CUI [2,2])
C0349410 (UMLS CUI [3])
Pregnancy | Breast Feeding
Item
pregnancy and breast-feeding.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])