Chronic Lymphocytic Leukemia Measurable | Prolymphocytic Leukemia Due to CLL
Item
patient must have documentation of histologically confirmed and measurable chronic lymphocytic leukemia (cll) or prolymphocytic leukemia (pll) arising from cll;
boolean
C0023434 (UMLS CUI [1,1])
C1513040 (UMLS CUI [1,2])
C0023486 (UMLS CUI [2,1])
C0678226 (UMLS CUI [2,2])
C0023434 (UMLS CUI [2,3])
Progressive Disease Symptomatic
Item
patient must have symptomatic and progressive disease;
boolean
C1335499 (UMLS CUI [1,1])
C0231220 (UMLS CUI [1,2])
Alkylating Agents | Fludarabine refractory
Item
patient must have received prior alkylating agent(s) and be fludarabine refractory;
boolean
C0002073 (UMLS CUI [1])
C0059985 (UMLS CUI [2,1])
C0205269 (UMLS CUI [2,2])
Organ function
Item
patient must have the adequate organ functions;
boolean
C0678852 (UMLS CUI [1])
ECOG performance status
Item
patient's eastern cooperative oncology group performance (ecog) status must be 0-2;
boolean
C1520224 (UMLS CUI [1])
Prolymphocytic Leukemia de novo
Item
patient with de novo pll;
boolean
C0023486 (UMLS CUI [1,1])
C1515568 (UMLS CUI [1,2])
Secondary Malignant Neoplasm Limiting Continuance of life
Item
patient with secondary malignancy that will limit survival ≤5 years;
boolean
C3266877 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0038952 (UMLS CUI [1,3])
Allogeneic bone marrow transplantation | Autologous bone marrow transplant | Peripheral Stem Cell Transplantation
Item
patient with prior allogenic or autologous bone marrow transplant or peripheral blood stem cell transplant ≤12 months;
boolean
C0149615 (UMLS CUI [1])
C0194037 (UMLS CUI [2])
C0242602 (UMLS CUI [3])
Investigational New Drugs | Pharmaceutical Preparations Purpose Investigational
Item
patient receiving an investigational agent or an approved agent for an investigational purpose within last 4 weeks prior to study entry;
boolean
C0013230 (UMLS CUI [1])
C0013227 (UMLS CUI [2,1])
C1285529 (UMLS CUI [2,2])
C1517586 (UMLS CUI [2,3])
Deficiency of glucose-6-phosphate dehydrogenase
Item
patient with known history of glucose-6-phosphate dehydrogenase deficiency;
boolean
C2939465 (UMLS CUI [1])
Autoimmune hemolytic anemia
Item
patient with autoimmune hemolytic anemia;
boolean
C0002880 (UMLS CUI [1])
Central Nervous System Involvement
Item
patient with known central nervous system involvement;
boolean
C4050309 (UMLS CUI [1])
Bacterial Infections Serious Uncontrolled | Virus Diseases Serious Uncontrolled | Mycoses Serious Uncontrolled
Item
patient with active, uncontrolled serious bacterial, viral or fungal infections
boolean
C0004623 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0205318 (UMLS CUI [1,3])
C0042769 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C0205318 (UMLS CUI [2,3])
C0026946 (UMLS CUI [3,1])
C0205404 (UMLS CUI [3,2])
C0205318 (UMLS CUI [3,3])
Study Subject Participation Status
Item
the above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.
boolean
C2348568 (UMLS CUI [1])