Essential Hypertension Mild | Essential Hypertension Moderate | Sitting diastolic blood pressure
Item
mild to moderate essential hypertension : sitting diastolic blood pressure measured at screening and baseline(day1) are 95~114 mmhg inclusive and the difference between sitting diastolic blood pressures measured at day -14 and baseline(day1) is under 7mmhg.
boolean
C0085580 (UMLS CUI [1,1])
C2945599 (UMLS CUI [1,2])
C0085580 (UMLS CUI [2,1])
C0205081 (UMLS CUI [2,2])
C1319894 (UMLS CUI [3])
Informed Consent
Item
subjects who agree to participate in this sudy and give written informed consent
boolean
C0021430 (UMLS CUI [1])
Comprehension Study Protocol | Protocol Compliance
Item
subjects considered to understand the study, be cooperative, and able to be followed-up until the end of the study
boolean
C0162340 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])
C0525058 (UMLS CUI [2])
Sitting diastolic blood pressure | Hypertension, severe
Item
the sitting dbp is less than 94mmhg or more than 115mmhg or severe hypertensive patient with sitting systolic blood pressure over 200mmhg
boolean
C1319894 (UMLS CUI [1])
C4013784 (UMLS CUI [2])
Secondary hypertension
Item
patients with secondary hypertension
boolean
C0155616 (UMLS CUI [1])
Kidney Disease Severe | Serum creatinine raised | Gastrointestinal Disease Severe | Hematological Disease Severe | Liver disease Severe | Aspartate aminotransferase increased | Alanine aminotransferase increased | Investigational New Drug Absorption Affected | Investigational New Drug Disposition Affected | Investigational New Drug Metabolism Affected | Investigational New Drug Excretion Affected
Item
patients with severe renal(creatinine more 1.5 times than upper limit of normal), gastrointestinal, hematological or hepatic(ast, alt more 2 twice more than upper limit of normal)disease etc. which might affect absorption, disposition, metabolism or excretion of the drug
boolean
C0022658 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0700225 (UMLS CUI [2])
C0017178 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0018939 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
C0023895 (UMLS CUI [5,1])
C0205082 (UMLS CUI [5,2])
C0151904 (UMLS CUI [6])
C0151905 (UMLS CUI [7])
C0013230 (UMLS CUI [8,1])
C0678745 (UMLS CUI [8,2])
C0392760 (UMLS CUI [8,3])
C0013230 (UMLS CUI [9,1])
C0678755 (UMLS CUI [9,2])
C0392760 (UMLS CUI [9,3])
C0013230 (UMLS CUI [10,1])
C0025520 (UMLS CUI [10,2])
C0392760 (UMLS CUI [10,3])
C0013230 (UMLS CUI [11,1])
C0683141 (UMLS CUI [11,2])
C0392760 (UMLS CUI [11,3])
Hypotension, Orthostatic
Item
patients with postural hypotension
boolean
C0020651 (UMLS CUI [1])
Insulin-Dependent Diabetes Mellitus Severe | Diabetic - poor control | Glycosylated hemoglobin A | Oral hypoglycemic | Therapy regimen changed | Insulin regime
Item
patients with sever insulin dependent diabetes mellitus or uncontrolled diabetes mellitus(hba1c>9%, regimen change of oral hypoglycemic agents within 3 months, treated insulin before screening)
boolean
C0011854 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0421258 (UMLS CUI [2])
C0019018 (UMLS CUI [3])
C0359086 (UMLS CUI [4])
C1141862 (UMLS CUI [5])
C0557978 (UMLS CUI [6])
Myocardial Infarction | Coronary Artery Disease Severe | Heart failure | Valvular defects
Item
patients with a history of myocardial infarction, severe coronary artery disease or clinically significant heart failure or valvular defect in last 6 months
boolean
C0027051 (UMLS CUI [1])
C1956346 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C0018801 (UMLS CUI [3])
C2748945 (UMLS CUI [4])
Cachexia | Autoimmune Diseases | Connective Tissue Diseases
Item
patients with consumptive disease, autoimmune disease, connective tissue disease
boolean
C0006625 (UMLS CUI [1])
C0004364 (UMLS CUI [2])
C0009782 (UMLS CUI [3])
Hepatitis B | Hepatitis C
Item
patients with a history of type b or c hepatitis
boolean
C0019163 (UMLS CUI [1])
C0019196 (UMLS CUI [2])
HIV Infection | Hepatitis
Item
patients with hiv or hepatitis
boolean
C0019693 (UMLS CUI [1])
C0019158 (UMLS CUI [2])
Laboratory test result abnormal
Item
patients with clinically significant laboratory abnormality
boolean
C0438215 (UMLS CUI [1])
Pharmaceutical Preparations Affecting Blood Pressure | Therapeutic procedure Affecting Blood Pressure
Item
patients receiving any drugs known to affect blood pressure or medical treatments that can influence the blood pressure
boolean
C0013227 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0005823 (UMLS CUI [1,3])
C0087111 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C0005823 (UMLS CUI [2,3])
Allergy to angiotensin II receptor antagonist | Medical contraindication Angiotensin II receptor antagonist
Item
patients with allergy or contraindication to any angiotensin ii receptor antagonists
boolean
C2585204 (UMLS CUI [1])
C1301624 (UMLS CUI [2,1])
C0521942 (UMLS CUI [2,2])
Childbearing Potential Hysterectomy Lacking | Childbearing Potential Postmenopausal state Absent
Item
female of childbearing potential who does not undergo hysterectomy or is not post-menopausal
boolean
C3831118 (UMLS CUI [1,1])
C0020699 (UMLS CUI [1,2])
C0332268 (UMLS CUI [1,3])
C3831118 (UMLS CUI [2,1])
C0232970 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
Substance Use Disorders
Item
patients judged to have a history of alcohol or drug abuse by the investigator
boolean
C0038586 (UMLS CUI [1])
Body Weight Average
Item
patients with average weight > +35% or <-15% in modified metropolitan life insurance table
boolean
C0005910 (UMLS CUI [1,1])
C1510992 (UMLS CUI [1,2])
Study Subject Participation Status
Item
patients participated other clinical trial 3 months before screening
boolean
C2348568 (UMLS CUI [1])
Study Subject Participation Status Inappropriate
Item
patients judged to be inappropriate for this study by the investigator with other reasons
boolean
C2348568 (UMLS CUI [1,1])
C1548788 (UMLS CUI [1,2])