full-aged
Item
subjects must be 18 years of age or older,
boolean
C0001779 (UMLS CUI [1])
normal teeth
Item
have at least six natural teeth,
boolean
C0426482 (UMLS CUI [1])
periodontal disease
Item
have established periodontal disease (established at the screening examination),
boolean
C0031090 (UMLS CUI [1])
type 2 diabetes
Item
have a history of type 2 diabetes of at least six months with hbalc > 7.1%.
boolean
C0011860 (UMLS CUI [1])
under the care of a periodontist
Item
subjects will be excluded from the study if they are presently under the care of a periodontist;
boolean
C0580931 (UMLS CUI [1,1])
C0260115 (UMLS CUI [1,2])
antibiotic treatment
Item
have had antibiotic treatment within the previous three months;
boolean
C0003232 (UMLS CUI [1])
antibiotic prophylaxis
Item
have conditions that require antibiotic prophylaxis for dental treatment;
boolean
C0282638 (UMLS CUI [1])
hypersensitivities
Item
have allergies to iodine, doxycycline, metronidazole, or chlorhexidine;
boolean
C0020517 (UMLS CUI [1,1])
C0021968 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0013090 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C0025872 (UMLS CUI [3,2])
C0020517 (UMLS CUI [4,1])
C0008196 (UMLS CUI [4,2])
blood dyscrasias
Item
have blood dyscrasias;
boolean
C0018939 (UMLS CUI [1])
pregnant or breast feeding
Item
are pregnant or breast feeding;
boolean
C0032961 (UMLS CUI [1,1])
C0006147 (UMLS CUI [1,2])
cognitive impairment
Item
have severe cognitive or communication impairment;
boolean
C0338656 (UMLS CUI [1])
cardiac pacemaker
Item
have a cardiac pacemaker;
boolean
C0030163 (UMLS CUI [1])
cancer chemotherapy
Item
are under cancer chemotherapy;
boolean
C0392920 (UMLS CUI [1])
low life expectancy
Item
are medically unstable or have a life expectancy of less than two years;
boolean
C1504437 (UMLS CUI [1])
C0438114 (UMLS CUI [2])
concomitant medication
Item
are currently taking disulfiram, phenobarbital, lithium, terfenadine, astemizole, or warfarin;
boolean
C2347852 (UMLS CUI [1])
unavailable
Item
or are out of town or otherwise unavailable for more than three consecutive months of the year.
boolean
C0686905 (UMLS CUI [1])