Gender | African American
Item
african american women: individuals will be considered to be african american if they self-identify as african american and were born in the united states. further they must describe both parents as being african american.
boolean
C0079399 (UMLS CUI [1])
C0085756 (UMLS CUI [2])
Gender | Caucasians
Item
caucasian women: individuals will be considered to be caucasian if they self-identify as caucasian.
boolean
C0079399 (UMLS CUI [1])
C0043157 (UMLS CUI [2])
Healthy Volunteers | Normal Volunteers | Full blood count normal | Glucose normal | BUN/Creatinine ratio Normal | Liver Function Tests Normal | Thyroid Function Tests Normal
Item
healthy volunteers: the potential enrollee must self identify as a normal volunteer and have this confirmed by having at the screening visit a normal complete blood count, glucose, bun creatinine, liver and thyroid panel.
boolean
C1708335 (UMLS CUI [1])
C3661466 (UMLS CUI [2])
C0427692 (UMLS CUI [3])
C0860800 (UMLS CUI [4])
C0201922 (UMLS CUI [5,1])
C0205307 (UMLS CUI [5,2])
C0023901 (UMLS CUI [6,1])
C0205307 (UMLS CUI [6,2])
C0040130 (UMLS CUI [7,1])
C0205307 (UMLS CUI [7,2])
Age | Triglycerides measurement | Early adulthood | Postmenopausal state
Item
age between 18 and 65 years: this age range is chosen because tg levels across the lifespan from early adulthood through to postmenopausal status. weare using 65 years of age as a conventional upper limit. in addition, 65 years of age has been used as an age category cut-off by national health and nutrition examination surveys. our goal is to detect ethnic differences in the pathways that allow vascular disease to develop. enrolling women between the ages of 18 and 65 years, maximizes our ability to detect differences in mechanism of action that are truly secondary to ethnicity.
boolean
C0001779 (UMLS CUI [1])
C0202236 (UMLS CUI [2])
C0680085 (UMLS CUI [3])
C0232970 (UMLS CUI [4])
Body Weight | DXA Scan Limitation
Item
weight less than 136 kg (300 lbs): this weight restriction is necessitated by the limitations of the dxa scanner. the dxa platform cannot accommodate subjects who weigh more than 136 kg.
boolean
C0005910 (UMLS CUI [1])
C1959592 (UMLS CUI [2,1])
C0449295 (UMLS CUI [2,2])
Body mass index | Gender | Ethnic group | Obesity
Item
bmi between 20 and 45 kg/m2: women in both ethnic groups will be recruited across bmi nonobese and obese categories. therefore we will enroll approximately equal numbers of women from each ethnic group in both bmi categories bmi between 20 and 30 kg/m(2) and bmi between 30 and 45 kg/m(2).
boolean
C1305855 (UMLS CUI [1])
C0079399 (UMLS CUI [2])
C0015031 (UMLS CUI [3])
C0028754 (UMLS CUI [4])
Barrier Contraception Refused | Pregnancy | Pregnancy Tests Frequency | Sexual Abstinence Requirement | Barrier Contraception Requirement
Item
refusal to agree to use barrier contraception: the dxa scan and ct scan should not be performed if the participant is pregnant. in addition, tg levels are directly affected by pregnancy. even though we will perform pregnancy tests within 7 days of each visit, we also require that the subject agree to abstinence or barrier contraception throughout the study.
boolean
C0004764 (UMLS CUI [1,1])
C1705116 (UMLS CUI [1,2])
C0032961 (UMLS CUI [2])
C0032976 (UMLS CUI [3,1])
C0439603 (UMLS CUI [3,2])
C0036899 (UMLS CUI [4,1])
C1514873 (UMLS CUI [4,2])
C0004764 (UMLS CUI [5,1])
C1514873 (UMLS CUI [5,2])
Pharmaceutical Preparations Affecting Parameters Investigational | Adrenal Cortex Hormones | Contraceptives, Oral | Oral hypoglycemic | Hypoglycemic Agents Injection | Hypolipidemic Agents | Antihypertensive Agents | Antipsychotic Agents
Item
medications which affect parameters under investigation: examples include corticosteroids, oral contraceptives, hypoglycemic (oral or injection), hypolipidemic, antihypertensive and antipsychotic agents. oral contraceptives, in particular, are exclusion criteria because the estrogen component of oral contraceptives increase tg levels and would therefore obscure the effect of the test meal on tg levels.
boolean
C0013227 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0449381 (UMLS CUI [1,3])
C1517586 (UMLS CUI [1,4])
C0001617 (UMLS CUI [2])
C0009905 (UMLS CUI [3])
C0359086 (UMLS CUI [4])
C0020616 (UMLS CUI [5,1])
C1828121 (UMLS CUI [5,2])
C0086440 (UMLS CUI [6])
C0003364 (UMLS CUI [7])
C0040615 (UMLS CUI [8])
Pharmaceutical Preparations Affecting Parameters Investigational | Diabetes Mellitus | Thyroid Disease | Liver disease | Pancreatitis | Nephrotic Syndrome
Item
medical conditions which affect parameters under investigation: examples include diabetes, thyroid disease, liver disease, pancreatitis, nephrotic syndrome.
boolean
C0013227 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0449381 (UMLS CUI [1,3])
C1517586 (UMLS CUI [1,4])
C0011849 (UMLS CUI [2])
C0040128 (UMLS CUI [3])
C0023895 (UMLS CUI [4])
C0030305 (UMLS CUI [5])
C0027726 (UMLS CUI [6])
Hispanics | Gender | White Hispanic | Relationship Triglycerides Insulin Resistance
Item
hispanics: the relationship between tg and insulin resistance in hispanic white women is midway between african american and caucasian women. therefore in this initial study to be able to determine the maximum ethnic difference in the relationship between tg and insulin resistance, we will enroll in this protocol study women who self-identify as african american and caucasian and not enroll women who self-identify as hispanic.
boolean
C0086409 (UMLS CUI [1])
C0079399 (UMLS CUI [2])
C1533021 (UMLS CUI [3])
C0439849 (UMLS CUI [4,1])
C0041004 (UMLS CUI [4,2])
C0021655 (UMLS CUI [4,3])