Inclusion criteria Insulin-Dependent Diabetes Mellitus
Item
patients with t1dm inclusion criteria:
boolean
C1512693 (UMLS CUI [1,1])
C0011854 (UMLS CUI [1,2])
Age
Item
1. age greater than 18
boolean
C0001779 (UMLS CUI [1])
Medical History Consistent with Insulin-Dependent Diabetes Mellitus
Item
2. history consistent with t1dm
boolean
C0262926 (UMLS CUI [1,1])
C0332290 (UMLS CUI [1,2])
C0011854 (UMLS CUI [1,3])
Obesity Absent | Body mass index
Item
1. non-obese (bmi less than 35 kg/m(2)), and
boolean
C0028754 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C1305855 (UMLS CUI [2])
Insulin Sensitivity Normal | Insulin U/day
Item
2. normal insulin sensitivity (as judged by insulin requirements less than or equal to 0.8 unit/kg/day).
boolean
C0920563 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
C0021641 (UMLS CUI [2,1])
C0456683 (UMLS CUI [2,2])
Low C-peptide levels
Item
3. low c-peptide (less than or equal to 0.6 ng/ml)
boolean
C4013229 (UMLS CUI [1])
Inclusion criteria Pancreas Transplantation
Item
pancreas transplant patient inclusion criteria:
boolean
C1512693 (UMLS CUI [1,1])
C0030275 (UMLS CUI [1,2])
Age
Item
1. age greater than 18
boolean
C0001779 (UMLS CUI [1])
Medical History Consistent with Insulin-Dependent Diabetes Mellitus
Item
2. history consistent with t1dm (as above) prior to pancreas transplant.
boolean
C0262926 (UMLS CUI [1,1])
C0332290 (UMLS CUI [1,2])
C0011854 (UMLS CUI [1,3])
Allograft pancreas Function Normal
Item
3. normal pancreas allograft function for at least the preceding 1 year.
boolean
C1720304 (UMLS CUI [1,1])
C0031843 (UMLS CUI [1,2])
C0205307 (UMLS CUI [1,3])
Rejection episode Absent
Item
4. no acute rejection episodes within the past year.
boolean
C0877542 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Inclusion criteria Control Group
Item
control patient inclusion criteria:
boolean
C1512693 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
Age
Item
1. age greater than 18
boolean
C0001779 (UMLS CUI [1])
History of diabetes mellitus Absent
Item
2. no history of diabetes.
boolean
C0455488 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
Fasting blood glucose measurement
Item
3. fasting blood glucose less than 100 mg/dl.
boolean
C0428568 (UMLS CUI [1])
Oral Glucose Tolerance Test Normal
Item
4. normal oral glucose tolerance.
boolean
C0029161 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
Body mass index
Item
5. bmi less than 35 kg/m(2)
boolean
C1305855 (UMLS CUI [1])
Exclusion Criteria Patients All
Item
exclusion criteria for all:
boolean
C0680251 (UMLS CUI [1,1])
C0030705 (UMLS CUI [1,2])
C0444868 (UMLS CUI [1,3])
Liver Dysfunction | Medical History | Physical Examination | Liver Function Tests Standard | AST level abnormal | ALT level abnormal | Bilirubin total abnormal | Direct bilirubin abnormal | alkaline phosphatase abnormal
Item
1. liver dysfunction as determined by history, physical examination, and standard liver function testing (abnormal values for ast, alt, total/direct bilirubin, alkaline phosphatase)
boolean
C0086565 (UMLS CUI [1])
C0262926 (UMLS CUI [2])
C0031809 (UMLS CUI [3])
C0023901 (UMLS CUI [4,1])
C1442989 (UMLS CUI [4,2])
C0580475 (UMLS CUI [5])
C0580469 (UMLS CUI [6])
C3203647 (UMLS CUI [7])
C1963962 (UMLS CUI [8])
C0740888 (UMLS CUI [9])
Blood Coagulation Disorders
Item
2. coagulopathy
boolean
C0005779 (UMLS CUI [1])
Pregnancy
Item
3. pregnancy
boolean
C0032961 (UMLS CUI [1])
Breast Feeding
Item
4. current breast feeding
boolean
C0006147 (UMLS CUI [1])
Monoamine Oxidase Inhibitors | Levodopa
Item
5. use of mao inhibitors or levodopa
boolean
C0026457 (UMLS CUI [1])
C0023570 (UMLS CUI [2])
Medical contraindication Magnetic Resonance Imaging
Item
6. patients with a contraindication to mri scanning.
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])