Diabetes Mellitus, Non-Insulin-Dependent
Item
diagnosed with type 2 diabetes.
boolean
C0011860 (UMLS CUI [1])
Metformin | Sulfonylurea
Item
have been treated with one of the following treatment regimens for at least three months prior to screening: *metformin alone; *sulfonylurea (su) alone;
boolean
C0025598 (UMLS CUI [1])
C0038766 (UMLS CUI [2])
Thiazolidinediones | Metformin | Sulfonylurea
Item
*thiazolidinedione (tzd) alone; *a combination of metformin and su; *a combination of metformin and tzd.
boolean
C1257987 (UMLS CUI [1])
C0025598 (UMLS CUI [2])
C0038766 (UMLS CUI [3])
Glycosylated hemoglobin A
Item
hba1c between 7.1% and 10.0%, inclusive.
boolean
C0019018 (UMLS CUI [1])
Body mass index
Item
body mass index (bmi) > 25 kg/m^2 and < 45 kg/m^2
boolean
C1305855 (UMLS CUI [1])
Study Subject Participation Status | Interventional procedure | Therapeutic procedure | Operative Surgical Procedures | Investigational New Drugs
Item
have participated in an interventional, medical, surgical, or pharmaceutical study (a study in which an experimental drug, medical, or surgical treatment was given) within 30 days prior to screening.
boolean
C2348568 (UMLS CUI [1])
C0184661 (UMLS CUI [2])
C0087111 (UMLS CUI [3])
C0543467 (UMLS CUI [4])
C0013230 (UMLS CUI [5])
Medical contraindication Metformin | Medical contraindication Sulfonylurea | Medical contraindication Thiazolidinediones
Item
have characteristics contraindicating metformin, su, or tzd use.
boolean
C1301624 (UMLS CUI [1,1])
C0025598 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0038766 (UMLS CUI [2,2])
C1301624 (UMLS CUI [3,1])
C1257987 (UMLS CUI [3,2])
Glucocorticoid therapy systemic chronic | Topical glucocorticoid | Glucocorticoids Inhalation
Item
are receiving chronic (lasting longer than 2 weeks) systemic glucocorticoid therapy (excluding topical and inhaled preparations) or have received such therapy within 2 weeks immediately prior to screening.
boolean
C0744425 (UMLS CUI [1,1])
C0205373 (UMLS CUI [1,2])
C0205191 (UMLS CUI [1,3])
C0017712 (UMLS CUI [2])
C0017710 (UMLS CUI [3,1])
C0205535 (UMLS CUI [3,2])
Weight-Loss Agents
Item
have used any prescription drug to promote weight loss within 3 months prior to screening.
boolean
C0376606 (UMLS CUI [1])
Insulin
Item
are currently treated (for greater than 2 consecutive weeks) with any of the following excluded medications: *insulin within 3 months prior to screening;
boolean
C0021641 (UMLS CUI [1])
alpha-Glucosidase Inhibitors | Meglitinide | Pharmaceutical Preparations Affecting Gastrointestinal Motility
Item
*alpha-glucosidase inhibitors within 3 months prior to screening; *meglitinides within 3 months prior to screening; *drugs that directly affect gastrointestinal motility
boolean
C1299007 (UMLS CUI [1])
C0065880 (UMLS CUI [2])
C0013227 (UMLS CUI [3,1])
C0392760 (UMLS CUI [3,2])
C0017184 (UMLS CUI [3,3])