Age | Diabetes Mellitus, Non-Insulin-Dependent | Poor glycemic control
Item
males and females, 18 to 75 years old, with type 2 diabetes with inadequate glycemic control
boolean
C0001779 (UMLS CUI [1])
C0011860 (UMLS CUI [2])
C0342299 (UMLS CUI [3])
Insulin | Metformin | Thiazolidinediones
Item
subjects receiving insulin and metformin and/or a thiazolidinedione
boolean
C0021641 (UMLS CUI [1])
C0025598 (UMLS CUI [2])
C1257987 (UMLS CUI [3])
Body mass index
Item
body mass index <=45.0 kg/m2
boolean
C1305855 (UMLS CUI [1])
Creatinine measurement, serum | Gender
Item
serum creatinine <1.5 mg/dl for men or <1.4 mg/dl for women
boolean
C0201976 (UMLS CUI [1])
C0079399 (UMLS CUI [2])
Proteinuria Absent | Albumin To Creatinine Protein Ratio Measurement | Protein measurement, urine, quantitative 24 hour
Item
no overt proteinuria (in subjects with a microalbumin/creatinine ratio ≥300 mg/g, the 24-hour urinary excretion of total protein must be <3 g/24 hrs)
boolean
C0033687 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0486293 (UMLS CUI [2])
C0202204 (UMLS CUI [3])
Diabetes Mellitus, Insulin-Dependent
Item
history of type 1 diabetes
boolean
C0011854 (UMLS CUI [1])
Aspartate aminotransferase increased | Alanine aminotransferase increased
Item
ast and/or alt >2.5 times the upper limit of normal
boolean
C0151904 (UMLS CUI [1])
C0151905 (UMLS CUI [2])
Elevated creatine kinase
Item
creatinine kinase ≥3 times the upper limit of normal
boolean
C0151576 (UMLS CUI [1])
Diabetic - poor control Severe Symptoms
Item
symptoms of severely uncontrolled diabetes
boolean
C0421258 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C1457887 (UMLS CUI [1,3])
Loss of hypoglycemic warning
Item
history of hypoglycemic unawareness
boolean
C0342317 (UMLS CUI [1])
Cardiovascular Diseases Unstable | Kidney Diseases Unstable | Liver diseases Unstable | Hematological Disease Unstable | Malignant Neoplasms Unstable | Endocrine System Diseases Unstable | Mental disorders Unstable | Rheumatism Unstable | Cardiovascular Diseases Serious | Kidney Diseases Serious | Liver diseases Serious | Hematological Disease Serious | Malignant Neoplasms Serious | Endocrine System Diseases Serious | Mental disorders Serious | Rheumatism Serious
Item
currently unstable or serious cardiovascular, renal, hepatic, hematological, oncological, endocrine, psychiatric, or rheumatic diseases
boolean
C0007222 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C0022658 (UMLS CUI [2,1])
C0443343 (UMLS CUI [2,2])
C0023895 (UMLS CUI [3,1])
C0443343 (UMLS CUI [3,2])
C0018939 (UMLS CUI [4,1])
C0443343 (UMLS CUI [4,2])
C0006826 (UMLS CUI [5,1])
C0443343 (UMLS CUI [5,2])
C0014130 (UMLS CUI [6,1])
C0443343 (UMLS CUI [6,2])
C0004936 (UMLS CUI [7,1])
C0443343 (UMLS CUI [7,2])
C0035435 (UMLS CUI [8,1])
C0443343 (UMLS CUI [8,2])
C0007222 (UMLS CUI [9,1])
C0205404 (UMLS CUI [9,2])
C0022658 (UMLS CUI [10,1])
C0205404 (UMLS CUI [10,2])
C0023895 (UMLS CUI [11,1])
C0205404 (UMLS CUI [11,2])
C0018939 (UMLS CUI [12,1])
C0205404 (UMLS CUI [12,2])
C0006826 (UMLS CUI [13,1])
C0205404 (UMLS CUI [13,2])
C0014130 (UMLS CUI [14,1])
C0205404 (UMLS CUI [14,2])
C0004936 (UMLS CUI [15,1])
C0205404 (UMLS CUI [15,2])
C0035435 (UMLS CUI [16,1])
C0205404 (UMLS CUI [16,2])