type 2 diabetes
Item
type 2 diabetes
boolean
C0011860 (UMLS CUI [1])
antidiabetics, insulin, thiazolidinediones
Item
not currently on antihyperglycemic agent (aha) or aha monotherapy (not to include treatment with insulin or thiazolidinediones [i.e., peroxisome proliferator activated receptor-gamma, pparγ agents])
boolean
C0935929 (UMLS CUI [1])
C0557978 (UMLS CUI [2])
C1257987 (UMLS CUI [3])
gender, childbearing potential, postmenopausal, female sterilization
Item
male or a female of non-childbearing potential. women must be postmenopausal or premenopausal and documented surgically sterilized
boolean
C0079399 (UMLS CUI [1])
C3831118 (UMLS CUI [2,1])
C0232970 (UMLS CUI [2,2])
C0015787 (UMLS CUI [2,3])
BMI
Item
a body mass index (bmi) that is > 20 and ≤ 40 kg/m2
boolean
C1305855 (UMLS CUI [1])
type 1 diabetes
Item
history of type 1 diabetes or assessed by the investigator as possibly having type 1 diabetes
boolean
C0011854 (UMLS CUI [1])
ketoacidosis, diabetic retinopathy, nephropathy, neuropathy
Item
history of ketoacidosis; clinically unstable or rapidly progressive diabetic retinopathy, nephropathy, neuropathy
boolean
C0011880 (UMLS CUI [1])
C0011884 (UMLS CUI [2])
C0011881 (UMLS CUI [3])
C0011882 (UMLS CUI [4])
combination anti-hyperglycemic therapy, insulin or thiazolidinediones
Item
treatment for diabetes within 3 months of study participation with combination anti-hyperglycemic therapy, insulin or thiazolidinediones (e.g., rosiglitazone or pioglitazone)
boolean
C0013218 (UMLS CUI [1,1])
C0935929 (UMLS CUI [1,2])
C0557978 (UMLS CUI [2])
C1257987 (UMLS CUI [3])
oral corticosteroid therapy, digoxin, warfarin, warfarin-like anticoagulants, theophylline, anti-dysrhythmic or anti-seizure medications, immunosuppressants, or anti-neoplastic agents, or herbal remedies
Item
oral corticosteroid medications within 2 weeks prior to study participation, or requires digoxin, warfarin, warfarin-like anticoagulants, theophylline, anti-dysrhythmic or anti-seizure medications, immunosuppressants, or anti-neoplastic agents, or herbal remedies
boolean
C0574135 (UMLS CUI [1])
C0012265 (UMLS CUI [2])
C0043031 (UMLS CUI [3])
C0003280 (UMLS CUI [4])
C0039771 (UMLS CUI [5])
C1979623 (UMLS CUI [6])
C0003299 (UMLS CUI [7])
C0021081 (UMLS CUI [8])
C0003392 (UMLS CUI [9])
C0721997 (UMLS CUI [10])
hiv, aids
Item
history of acquired immunodeficiency syndrome (aids) or human immunodeficiency virus (hiv)
boolean
C0019682 (UMLS CUI [1])
C0001175 (UMLS CUI [2])
gastrointestinal disorder, extensive bowel or gastric surgery
Item
history of gastrointestinal problems or disorders or extensive bowel or gastric surgery
boolean
C0017178 (UMLS CUI [1])
C0192573 (UMLS CUI [2,1])
C0205231 (UMLS CUI [2,2])
cardiovascular disease
Item
history of significant or unstable cardiovascular disease
boolean
C0007222 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
history of neoplastic disease
Item
history of neoplastic disease
boolean
C2735088 (UMLS CUI [1])
hepatic disease
Item
history of hepatic disease
boolean
C0023895 (UMLS CUI [1])
seizures, epilepsy, other neurologic disease
Item
history of seizures, epilepsy or other neurologic disease
boolean
C0036572 (UMLS CUI [1])
C0014544 (UMLS CUI [2])
C0027765 (UMLS CUI [3])
myelodysplastic disorder, hematological disorder
Item
history of myelodysplastic or pre-leukemic disorders or other severe hematological disorder
boolean
C1301355 (UMLS CUI [1])
C0018939 (UMLS CUI [2])