Age
Item
1. 25 to 79 years old.
boolean
C0001779 (UMLS CUI [1])
Informed Consent
Item
2. provide voluntary written informed consent to participate.
boolean
C0021430 (UMLS CUI [1])
smoking cigarettes: ____ pack-years history
Item
3. smoking history of at least 10 pack years (1 pack of cigarettes per day for 10 years).
boolean
C2230126 (UMLS CUI [1])
Chronic Obstructive Airway Disease
Item
4. diagnosis of chronic obstructive pulmonary disease.
boolean
C0024117 (UMLS CUI [1])
Physical activity Resulting in Shortness of breath
Item
5. become short of breath with physical activity.
boolean
C0026606 (UMLS CUI [1,1])
C0332294 (UMLS CUI [1,2])
C0013404 (UMLS CUI [1,3])
Pulmonary artery systolic pressure Elevated
Item
6. elevated systolic pulmonary artery pressures.
boolean
C0428643 (UMLS CUI [1,1])
C3163633 (UMLS CUI [1,2])
Pregnancy Absent | Breast Feeding Absent | Planned Pregnancy Absent
Item
7. not pregnant, nursing, or planning a pregnancy.
boolean
C0032961 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0006147 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0032992 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
Left ventricular ejection fraction
Item
1. left ventricular ejection fraction <30%.
boolean
C0428772 (UMLS CUI [1])
Myocardial Infarction | Cerebrovascular accident
Item
2. heart attack or stroke within the last 6 months.
boolean
C0027051 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
Lung excision
Item
3. history of lung resection surgery.
boolean
C0396565 (UMLS CUI [1])
Use of supplemental oxygen hours/day
Item
4. use of supplemental oxygen >20 hours/day.
boolean
C4067893 (UMLS CUI [1,1])
C0556974 (UMLS CUI [1,2])
Blood Donation | Blood Loss
Item
5. blood donation or significant blood loss within the last 56 days.
boolean
C0005794 (UMLS CUI [1])
C3163616 (UMLS CUI [2])
Plasma Donation
Item
6. plasma donation within the last 14 days.
boolean
C0032105 (UMLS CUI [1,1])
C0680854 (UMLS CUI [1,2])
Study Subject Participation Status | Investigational New Drugs
Item
7. use of any drugs for another research study within the last 30 days.
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
Vasodilator Agents | Nitrates Active Long-term | Epoprostenol Analog | Endothelin receptor antagonist | Phosphodiesterase Inhibitors
Item
8. use of vasodilators, long acting nitrates, prostacyclin analogs, endothelin antagonists, or phosphodiesterase inhibitor drugs within the last 14 days.
boolean
C0042402 (UMLS CUI [1])
C0028125 (UMLS CUI [2,1])
C0205177 (UMLS CUI [2,2])
C0443252 (UMLS CUI [2,3])
C0033567 (UMLS CUI [3,1])
C0243071 (UMLS CUI [3,2])
C1134681 (UMLS CUI [4])
C0031638 (UMLS CUI [5])
Hepatitis B surface antigen positive | Hepatitis C antibody positive
Item
9. positive blood screen hepatitis b surface antigen (hbsag) or hepatitis c antibody.
boolean
C0149709 (UMLS CUI [1])
C0281863 (UMLS CUI [2])
major surgery
Item
10. major surgery within the last 28 days.
boolean
C0679637 (UMLS CUI [1])
Medical condition compromises patient safety | Medical condition compromises Validity Research results | Medical condition Interferes with Clinical Trial Completion
Item
11. any other medical condition that may jeopardize the safety of the subject, the validity of the study results, or interfere with the completion of the study according to the protocol.
boolean
C3843040 (UMLS CUI [1,1])
C2945640 (UMLS CUI [1,2])
C1113679 (UMLS CUI [1,3])
C3843040 (UMLS CUI [2,1])
C2945640 (UMLS CUI [2,2])
C2349101 (UMLS CUI [2,3])
C0683954 (UMLS CUI [2,4])
C3843040 (UMLS CUI [3,1])
C0521102 (UMLS CUI [3,2])
C0008976 (UMLS CUI [3,3])
C0205197 (UMLS CUI [3,4])