Adenocarcinoma of prostate | Neuroendocrine Differentiation Absent | Adenocarcinoma of prostate Non-small cell
Item
histologically or cytologically confirmed adenocarcinoma (cancer that begins in cells that line certain internal organs and that have secretory properties) of the prostate, but not with neuroendocrine differentiation or of small cell histology
boolean
C0007112 (UMLS CUI [1])
C1709218 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0007112 (UMLS CUI [3,1])
C0445128 (UMLS CUI [3,2])
Chemotherapy Prostate carcinoma | Paclitaxel | docetaxel
Item
before chemotherapy for prostate cancer with regimen(s) containing paclitaxel or docetaxel
boolean
C0392920 (UMLS CUI [1,1])
C0600139 (UMLS CUI [1,2])
C0144576 (UMLS CUI [2])
C0246415 (UMLS CUI [3])
PSA Progression | Prostate specific antigen measurement
Item
documented prostate-specific antigen (psa) progression according to psa working group eligibility criteria with a psa greater than 5 nanogram per milliliter (ng/ml)
boolean
C4054264 (UMLS CUI [1])
C0201544 (UMLS CUI [2])
Androgen suppression | Serum testosterone measurement
Item
ongoing androgen deprivation with serum testosterone level of less than 50 nanogram per deciliter (ng/dl)
boolean
C1515985 (UMLS CUI [1])
C0428413 (UMLS CUI [2])
ECOG performance status | Karnofsky Performance Status
Item
eastern cooperative oncology group (ecog) performance status of less than or equal to 2 (karnofsky performance status greater than or equal 50 percentage)
boolean
C1520224 (UMLS CUI [1])
C0206065 (UMLS CUI [2])
Autoimmune Disease | Autoimmune Disease Uncontrolled | Steroid therapy Patient need for
Item
active or uncontrolled autoimmune disease that may require corticosteroid therapy
boolean
C0004364 (UMLS CUI [1])
C0004364 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
C0149783 (UMLS CUI [3,1])
C0686904 (UMLS CUI [3,2])
Comorbidity Serious | Comorbidity Uncontrolled | Communicable Disease Uncontrolled
Item
serious or uncontrolled co-existent non-malignant disease, including active and uncontrolled infection
boolean
C0009488 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0009488 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
C0009450 (UMLS CUI [3,1])
C0205318 (UMLS CUI [3,2])
Uncontrolled hypertension
Item
uncontrolled hypertension
boolean
C1868885 (UMLS CUI [1])
Heart Disease | Myocardial Infarction | Angina Pectoris Severe | Angina, Unstable | Heart Disease New York Heart Association Classification | Atherosclerosis Requirement Coronary Artery Bypass Surgery | Peripheral artery bypass Patient need for
Item
clinically significant heart disease as evidenced by a myocardial infarction in the past 12 months, severe or unstable angina, or new york heart association (nyha) class iii or iv heart disease (participants with a history of atherosclerotic vascular disease requiring coronary or peripheral artery bypass surgery may be enrolled provided the surgery occurred at least 2 years before to enrollment and after consultation with a cardiologist to insure that the disease is stable)
boolean
C0018799 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
C0002962 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0002965 (UMLS CUI [4])
C0018799 (UMLS CUI [5,1])
C1275491 (UMLS CUI [5,2])
C0004153 (UMLS CUI [6,1])
C1514873 (UMLS CUI [6,2])
C0010055 (UMLS CUI [6,3])
C3495795 (UMLS CUI [7,1])
C0686904 (UMLS CUI [7,2])
Gastrointestinal Diseases Interfere with Absorption Investigational New Drugs | Gastrointestinal Surgical Procedure Extensive Interferes with Absorption Investigational New Drugs
Item
history of gastrointestinal disorders (medical disorders or extensive surgery) which may interfere with the absorption of the study medication
boolean
C0017178 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0237442 (UMLS CUI [1,3])
C0013230 (UMLS CUI [1,4])
C0524722 (UMLS CUI [2,1])
C0205231 (UMLS CUI [2,2])
C0521102 (UMLS CUI [2,3])
C0237442 (UMLS CUI [2,4])
C0013230 (UMLS CUI [2,5])