Criteria Fulfill
Item
subjects must have
boolean
C0243161 (UMLS CUI [1,1])
C1550543 (UMLS CUI [1,2])
Prostate carcinoma High risk Biopsy | Prostate specific antigen measurement | Gleason score | TNM clinical staging
Item
biopsy-confirmed "high-risk" prostate cancer, defined as a. psa > 20, b. gleason score (gs) >/= 8, and/or c. clinical stage t3 disease per ajcc staging manual, 6th edition; or d. at least two out of three of the following: psa 10-19.9, gs = 7, or clinical stage = t2b / t2c.
boolean
C0600139 (UMLS CUI [1,1])
C0332167 (UMLS CUI [1,2])
C0005558 (UMLS CUI [1,3])
C0201544 (UMLS CUI [2])
C3203027 (UMLS CUI [3])
C3258246 (UMLS CUI [4])
Bone scan Negative
Item
a negative bone scan,
boolean
C0203668 (UMLS CUI [1,1])
C1513916 (UMLS CUI [1,2])
Fit and well | Operative Surgical Procedures Receive Ability
Item
be medically fit to undergo surgery as determined by treating urologist,
boolean
C0424576 (UMLS CUI [1])
C0543467 (UMLS CUI [2,1])
C1514756 (UMLS CUI [2,2])
C0085732 (UMLS CUI [2,3])
Age
Item
age > 18,
boolean
C0001779 (UMLS CUI [1])
Karnofsky Performance Status
Item
kps must be >/= 80,
boolean
C0206065 (UMLS CUI [1])
Radiotherapy to pelvis Absent | Chemotherapy Absent | Antiandrogen therapy Absent
Item
no prior pelvic radiation therapy, chemotherapy, or androgen deprivation,
boolean
C1536155 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0392920 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0279492 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
Invasive cancer Absent | Skin carcinoma | Disease Free of | Carcinoma in situ of bladder | Carcinoma in Situ Head and neck
Item
no prior invasive malignancy, except non- melanomatous skin cancer unless disease free for a minimum of 5 years. carcinoma in-situ of the bladder or head and neck region is permissible.
boolean
C0677898 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0699893 (UMLS CUI [2])
C0012634 (UMLS CUI [3,1])
C0332296 (UMLS CUI [3,2])
C0154091 (UMLS CUI [4])
C0007099 (UMLS CUI [5,1])
C0460004 (UMLS CUI [5,2])
Informed Consent
Item
subjects must freely sign informed consent to enroll in the study.
boolean
C0021430 (UMLS CUI [1])
Radiotherapy to pelvis | Chemotherapy | Antiandrogen therapy
Item
prior pelvic radiation therapy, chemotherapy, or androgen deprivation,
boolean
C1536155 (UMLS CUI [1])
C0392920 (UMLS CUI [2])
C0279492 (UMLS CUI [3])
Invasive cancer | Skin carcinoma | Carcinoma in situ of bladder | Carcinoma in Situ Head and neck | Disease Free of
Item
prior invasive malignancy, except non- melanomatous skin cancer, carcinoma in-situ of the bladder or head and neck region, unless disease free for a minimum of 5 years.
boolean
C0677898 (UMLS CUI [1])
C0699893 (UMLS CUI [2])
C0154091 (UMLS CUI [3])
C0007099 (UMLS CUI [4,1])
C0460004 (UMLS CUI [4,2])
C0012634 (UMLS CUI [5,1])
C0332296 (UMLS CUI [5,2])
Neoplasm Metastasis Bone scan | Neoplasm Metastasis CT scan | Neoplasm Metastasis MRI of Pelvis | Neoplasm Metastasis Plain chest X-ray
Item
metastatic disease as demonstrated by bone scan, ct scan or mri of the pelvis, or chest x-ray.
boolean
C0027627 (UMLS CUI [1,1])
C0203668 (UMLS CUI [1,2])
C0027627 (UMLS CUI [2,1])
C0040405 (UMLS CUI [2,2])
C0027627 (UMLS CUI [3,1])
C0203201 (UMLS CUI [3,2])
C0027627 (UMLS CUI [4,1])
C0039985 (UMLS CUI [4,2])
Pelvic lymph nodes Positive | CT scan Preoperative | MRI Preoperative | Lymph Node Involvement Suspected | Biopsy Patient need for
Item
pathologically documented positive pelvic lymph nodes. if pre-operative ct scan or mri (ordered at the discretion of the treating physicians) demonstrates lymph nodes which are suspicious for involvement, then biopsy must be undertaken and nodes proven negative before patient can enroll on this trial.
boolean
C0729595 (UMLS CUI [1,1])
C1514241 (UMLS CUI [1,2])
C0040405 (UMLS CUI [2,1])
C0445204 (UMLS CUI [2,2])
C0024485 (UMLS CUI [3,1])
C0445204 (UMLS CUI [3,2])
C0806692 (UMLS CUI [4,1])
C0750491 (UMLS CUI [4,2])
C0005558 (UMLS CUI [5,1])
C0686904 (UMLS CUI [5,2])
Anesthesia High risk
Item
declared high-risk for anesthesia by attending anesthesiologist, cardiologist, or other physician.
boolean
C0002903 (UMLS CUI [1,1])
C0332167 (UMLS CUI [1,2])
Radiotherapy to pelvis
Item
history of prior pelvic radiation therapy.
boolean
C1536155 (UMLS CUI [1])
Antiandrogen therapy | Chemotherapy
Item
history of androgen deprivation therapy or chemotherapy.
boolean
C0279492 (UMLS CUI [1])
C0392920 (UMLS CUI [2])