ID.1
Item
women with age ≥18 and ≤65 years
boolean
C0043210 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ID.2
Item
histological and/or cytological diagnosis of clinically non-metastatic breast cancer (c/ptall, c/pnall, cm0)
boolean
C0006142 (UMLS CUI [1,1])
C1334991 (UMLS CUI [1,2])
ID.3
Item
indication for integrated treatment with surgical intervention associated with adjuvant or neo-adjuvant chemotherapy, endocrinological and radiation therapy, including adjuvant or neo-adjuvant chemotherapy with anthracycline
boolean
C0087111 (UMLS CUI [1])
ID.4
Item
ecog (eastern cooperative oncology group) performance status ≤2
boolean
C1512162 (UMLS CUI [1])
ID.5
Item
normal kidney, hepatic and hematological function
boolean
C0678852 (UMLS CUI [1])
ID.6
Item
normal lv ejection fraction at baseline (≥50%)
boolean
C2024227 (UMLS CUI [1])
ID.7
Item
negative pregnancy test in fecund women
boolean
C0232973 (UMLS CUI [1])
ID.8
Item
metastatic breast cancer
boolean
C0027627 (UMLS CUI [1])
ID.9
Item
past radiation therapy and chemotherapy
boolean
C0279134 (UMLS CUI [1,1])
C1514457 (UMLS CUI [1,2])
ID.10
Item
hypertension and other cardiovascular risk factors
boolean
C0020538 (UMLS CUI [1,1])
C0850624 (UMLS CUI [1,2])
ID.11
Item
prior valvular heart disease
boolean
C0018824 (UMLS CUI [1])
ID.12
Item
cardiomyopathy
boolean
C0878544 (UMLS CUI [1])
ID.13
Item
chronic or acute congestive heart failure
boolean
C0264719 (UMLS CUI [1,1])
C0264722 (UMLS CUI [1,2])
ID.14
Item
lv systolic dysfunction (ejection fraction<50%)
boolean
C1277187 (UMLS CUI [1])
ID.15
Item
abnormal complete blood count
boolean
C0438216 (UMLS CUI [1])
ID.16
Item
pregnancy
boolean
C0032961 (UMLS CUI [1])
ID.17
Item
breast-feeding
boolean
C0006147 (UMLS CUI [1])