ID.1
Item
women with histological diagnosis of invasive breast cancer requiring neoadjuvant chemotherapy
boolean
C0853879 (UMLS CUI [1,1])
C4272610 (UMLS CUI [1,2])
ID.2
Item
t2 tumour or above
boolean
C0178759 (UMLS CUI [1])
ID.3
Item
who performance status of 0,1 or 2
boolean
C1298650 (UMLS CUI [1])
ID.4
Item
must consent to or have undergone a core biopsy for diagnosis of breast cancer and consent to undergo an additional core biopsy prior to the second cycle of chemotherapy (day 5 +/- day 21)
boolean
C1318309 (UMLS CUI [1])
ID.5
Item
written informed consent
boolean
C0021430 (UMLS CUI [1])
ID.6
Item
previous chemotherapy or radiotherapy to treated breast
boolean
C1514457 (UMLS CUI [1,1])
C0279134 (UMLS CUI [1,2])
ID.7
Item
evidence of metastatic disease or recurrent breast cancer or previous malignancy (some exceptions)
boolean
C0027627 (UMLS CUI [1])
ID.8
Item
calculated creatinine clearance < 40mls/min
boolean
C0373595 (UMLS CUI [1])
ID.9
Item
prior treatment with bisphosphonates in last year or known contraindications to bisphosphonate therapy
boolean
C1563145 (UMLS CUI [1])
ID.10
Item
concurrent tamoxifen or aromatase inhibitor medication
boolean
C0039286 (UMLS CUI [1,1])
C0593802 (UMLS CUI [1,2])
ID.11
Item
pregnant or lactating women
boolean
C0549206 (UMLS CUI [1,1])
C2828358 (UMLS CUI [1,2])
ID.12
Item
cardiac dysfunction that precludes use of anthracycline chemotherapy
boolean
C3277906 (UMLS CUI [1])
ID.13
Item
unwilling to have extra interim biopsy
boolean
C0558080 (UMLS CUI [1,1])
C0005560 (UMLS CUI [1,2])