Parkinson Disease
Item
the presence of idiopathic parkinson disease
boolean
C0030567 (UMLS CUI [1])
Dopaminergic Agents | Clinical Response Clear
Item
a clear clinical response to dopaminergic therapy treatment
boolean
C0013036 (UMLS CUI [1])
C4055223 (UMLS CUI [2,1])
C2963144 (UMLS CUI [2,2])
Hoehn and Yahr Stage
Item
hoehn and yahr stages < 3;
boolean
C3639483 (UMLS CUI [1])
disease length
Item
2-7 year duration from time of diagnosis.
boolean
C0872146 (UMLS CUI [1])
Mini-mental state examination score
Item
mini-mental status exam score of >24,
boolean
C2960235 (UMLS CUI [1])
Gender Childbearing Potential Lacking | Childbearing Potential Urine pregnancy test negative
Item
for females, non-child bearing potential or negative urine pregnancy test on day of [123i] 5-ia injection.
boolean
C0079399 (UMLS CUI [1,1])
C3831118 (UMLS CUI [1,2])
C0332268 (UMLS CUI [1,3])
C3831118 (UMLS CUI [2,1])
C0430057 (UMLS CUI [2,2])
Secondary Parkinson Disease
Item
secondary parkinsonism;
boolean
C0030569 (UMLS CUI [1])
Nicotine Dependence | Nicotine Use Disorder
Item
nicotine dependence or use within the previous 12 months prior to enrollment;
boolean
C0028043 (UMLS CUI [1])
C0376384 (UMLS CUI [2])
Aricept | donepezil | Exelon | rivastigmine | Cognex | Tacrine
Item
treatment with aricept (donepezil), exelon (rivastigmine), cognex (tacrine) within the past 30 days; treatment with medications that bind to the nicotinic receptor.
boolean
C0527315 (UMLS CUI [1])
C0527316 (UMLS CUI [2])
C0730987 (UMLS CUI [3])
C0649350 (UMLS CUI [4])
C0699954 (UMLS CUI [5])
C0039245 (UMLS CUI [6])
Laboratory Results Clinical Significance | Illness | Mental disorders
Item
clinically significant clinical laboratory value and/or medical or psychiatric illness;
boolean
C1254595 (UMLS CUI [1,1])
C2826293 (UMLS CUI [1,2])
C0221423 (UMLS CUI [2])
C0004936 (UMLS CUI [3])
Mini-mental state examination score
Item
mini-mental status exam score of ≤24.
boolean
C2960235 (UMLS CUI [1])
Thyroid Diseases | Gastrointestinal Diseases | Cardiovascular Diseases | Liver diseases | Kidney Diseases | Hematological Disease | Neoplastic disease | Endocrine System Diseases | nervous system disorder | Immunologic Deficiency Syndromes | Lung diseases | Illness | Mental disorders
Item
the subject has evidence of clinically significant thyroid disease, gastrointestinal, cardiovascular, hepatic, renal, hematologic, neoplastic, endocrine, neurologic, immunodeficiency, pulmonary, or other medical or psychiatric disorder;
boolean
C0040128 (UMLS CUI [1])
C0017178 (UMLS CUI [2])
C0007222 (UMLS CUI [3])
C0023895 (UMLS CUI [4])
C0022658 (UMLS CUI [5])
C0018939 (UMLS CUI [6])
C1882062 (UMLS CUI [7])
C0014130 (UMLS CUI [8])
C0027765 (UMLS CUI [9])
C0021051 (UMLS CUI [10])
C0024115 (UMLS CUI [11])
C0221423 (UMLS CUI [12])
C0004936 (UMLS CUI [13])
Investigational New Drugs
Item
the subject has received an investigational drug within 30 days of the screening visit;
boolean
C0013230 (UMLS CUI [1])
Pregnancy
Item
pregnancy
boolean
C0032961 (UMLS CUI [1])