Degenerative joint disease Medial compartment of knee | Degenerative joint disease Patellofemoral | Knee Replacement Unilateral Patient need for
Item
patient presents with non-inflammatory degenerative joint disease of the medial and patellofemoral compartments requiring a unilateral knee replacement.
boolean
C0029408 (UMLS CUI [1,1])
C0447799 (UMLS CUI [1,2])
C0029408 (UMLS CUI [2,1])
C0409325 (UMLS CUI [2,2])
C0086511 (UMLS CUI [3,1])
C0205092 (UMLS CUI [3,2])
C0686904 (UMLS CUI [3,3])
Age
Item
patient is 30 to 75 years of age, inclusive.
boolean
C0001779 (UMLS CUI [1])
Informed Consent
Item
patient is willing to consent to participate in the study by signing and dating an irb-approved consent form.
boolean
C0021430 (UMLS CUI [1])
Clinical Study Follow-up Postoperative Duration | Patient Availability of
Item
patient plans to be available for follow-up through five years postoperative.
boolean
C3274571 (UMLS CUI [1,1])
C0032790 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
C0030705 (UMLS CUI [2,1])
C0470187 (UMLS CUI [2,2])
Femur Bone Marrow Insufficient | Tibia Bone Marrow Insufficient | Malignant Neoplasms | Osteotomy of distal femur | Osteotomy of proximal tibia | Osteoporosis | Metabolic Bone Disorder
Item
patient is known to have insufficient femoral or tibial bone stock resulting from conditions such as cancer, distal femoral/proximal tibial osteotomy, significant osteoporosis or metabolic bone disorders.
boolean
C2698535 (UMLS CUI [1,1])
C0231180 (UMLS CUI [1,2])
C2698539 (UMLS CUI [2,1])
C0231180 (UMLS CUI [2,2])
C0006826 (UMLS CUI [3])
C0407483 (UMLS CUI [4])
C0407484 (UMLS CUI [5])
C0029456 (UMLS CUI [6])
C0005944 (UMLS CUI [7])
Immunocompromised Host | Autoimmune Diseases | Immunosuppression | Condition chronic | Response to antigens Ability inhibited | Therapeutic immunosuppression | Adrenal Cortex Hormones Large amount | Cytotoxic agent | Antilymphocytic serum | Therapeutic radiology procedure Dosage Large | Acquired Immunodeficiency Syndrome
Item
patient is immunosuppressed, has an autoimmune disorder, or an immunosuppressive disorder (i.e. chronic condition characterized by markedly inhibited ability to respond to antigenic stimuli.) examples of such conditions include patients who are on immunosuppressive therapy (corticosteroid hormones in large amounts, cytotoxic drugs, antilymphocytic serum or irradiation in large doses) or patients with acquired immunodeficiency syndrome (aids).
boolean
C0085393 (UMLS CUI [1])
C0004364 (UMLS CUI [2])
C4048329 (UMLS CUI [3])
C0348080 (UMLS CUI [4,1])
C0205191 (UMLS CUI [4,2])
C1314973 (UMLS CUI [5,1])
C0085732 (UMLS CUI [5,2])
C0311403 (UMLS CUI [5,3])
C0021079 (UMLS CUI [6])
C0001617 (UMLS CUI [7,1])
C3869890 (UMLS CUI [7,2])
C0304497 (UMLS CUI [8])
C3826731 (UMLS CUI [9])
C1522449 (UMLS CUI [10,1])
C0178602 (UMLS CUI [10,2])
C0549177 (UMLS CUI [10,3])
C0001175 (UMLS CUI [11])
Arthritis | Rheumatoid Arthritis
Item
patient has inflammatory arthritis (e.g. rheumatoid arthritis)
boolean
C0003864 (UMLS CUI [1])
C0003873 (UMLS CUI [2])
Body mass index
Item
patient has bmi greater than or equal to 40.
boolean
C1305855 (UMLS CUI [1])
Operative procedure on knee Major | Osteotomy of proximal tibia | Arthroplasty, Replacement, Partial Knee | Fracture Fixation failed
Item
patient has had major knee surgery in the past i.e. hto, unicondylar knee replacement, failed fracture fixation.
boolean
C0187769 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
C0407484 (UMLS CUI [2])
C0864243 (UMLS CUI [3])
C0016641 (UMLS CUI [4,1])
C0231175 (UMLS CUI [4,2])
local; infection | Sepsis
Item
patient has an active infection, local or systemic.
boolean
C1400591 (UMLS CUI [1])
C0243026 (UMLS CUI [2])
Physical Condition compromises Protocol Compliance | Emotional condition compromises Protocol Compliance | Nervous system disorder compromises Protocol Compliance | Substance Use Disorders | Mental disorders Serious | Nervous system disorder General | Parkinson Disease | Multiple Sclerosis
Item
patient has physical, emotional or neurological conditions that would compromise the patient's compliance with postoperative rehabilitation and followup (e.g.: drug or alcohol abuse, serious mental illness, or general neurological conditions such as parkinson, multiple sclerosis, etc.).
boolean
C3714565 (UMLS CUI [1,1])
C2945640 (UMLS CUI [1,2])
C0525058 (UMLS CUI [1,3])
C3843038 (UMLS CUI [2,1])
C2945640 (UMLS CUI [2,2])
C0525058 (UMLS CUI [2,3])
C0027765 (UMLS CUI [3,1])
C2945640 (UMLS CUI [3,2])
C0525058 (UMLS CUI [3,3])
C0038586 (UMLS CUI [4])
C0004936 (UMLS CUI [5,1])
C0205404 (UMLS CUI [5,2])
C0027765 (UMLS CUI [6,1])
C0205246 (UMLS CUI [6,2])
C0030567 (UMLS CUI [7])
C0026769 (UMLS CUI [8])
Deficiency of anterior cruciate ligament
Item
patient has acl deficiency in the study knee.
boolean
C0409310 (UMLS CUI [1])
Coxitis | Hip Replacement
Item
patient has hip arthritis and/or replacement.
boolean
C0263776 (UMLS CUI [1])
C0392806 (UMLS CUI [2])
Compartment Lateral Disease
Item
patient has lateral compartment disease.
boolean
C0447798 (UMLS CUI [1,1])
C0205093 (UMLS CUI [1,2])
C0012634 (UMLS CUI [1,3])
Pregnancy | Pregnancy, Planned
Item
patient is pregnant or plans to become pregnant during the course of the study.
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
Hypersensitivity Medical Device Materials
Item
patient has a known sensitivity to materials in the device.
boolean
C0020517 (UMLS CUI [1,1])
C0025080 (UMLS CUI [1,2])
C0520510 (UMLS CUI [1,3])